1 Result for "

YLL545

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YLL545" in MCE Product Catalog:

Cat. No.: HY-164551
CAS No.: 1423126-69-5
Target:  

VEGFR STAT ERK Apoptosis

Research Areas:  

Cancer

YLL545 is a type of vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor. YLL545 can inhibit VEGF-induced phosphorylation of VEGFR2 and the activation of downstream signaling factors (like phosphorylated STAT3 and phosphorylated ERK1/2) in human umbilical vein endothelial cells (HUVEC). YLL545 can suppress the proliferation, migration, invasion, and angiogenesis of HUVEC. YLL545 can induce apoptosis in breast cancer mice and inhibit tumor growth .
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