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acetophenone derivative

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (2) Apoptosis (2) COX (1) Drug Intermediate (1) mTOR (2) NF-κB (1) NO Synthase (2) Parasite (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2) TNF Receptor (1) Xanthine Oxidase (4)
By Research Areas:	Cancer (1) Cardiovascular Disease (2) Infection (1) Inflammation/Immunology (6) Metabolic Disease (5)

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Targets Recommended: Drug Derivative

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W012658

2-Methylacetophenone O-Methylacetophenone	Xanthine Oxidase	Metabolic Disease Inflammation/Immunology
2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a xanthine dehydrogenase (XDH) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust .

HY-N1731

2′-Hydroxy-5′-methoxyacetophenone	NF-κB COX TNF Receptor NO Synthase Reactive Oxygen Species (ROS) Parasite	Infection Metabolic Disease Inflammation/Immunology Cancer
2'-Hydroxy-5'-methoxyacetophenone is an acetophenone derivative with acaricidal activities. 2'-Hydroxy-5'-methoxyacetophenone attenuates the inﬂammatory response via NF-κB signaling pathway. 2'-Hydroxy-5'-methoxyacetophenone exhibits significant inhibitory activity against α-amylase, collagenase and aldose reductase (AR) with IC₅₀s of 0.928, 3.264 and 20.046 μM, highlighting its potential in combating diabetes. 2'-Hydroxy-5'-methoxyacetophenone exhibits anti-ovarian cancer activity .

HY-Y0106

2,6-Dihydroxyacetophenone	mTOR Xanthine Oxidase Apoptosis	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
2,6-Dihydroxyacetophenone, a polyphenolic derivative of Acetophenone (HY-Y0989), is an orally active mTOR inhibitor. 2,6-Dihydroxyacetophenone shows antioxidant activity. 2,6-Dihydroxyacetophenone inhibits cell growth and proliferation in CRC cells. 2,6-Dihydroxyacetophenone arrests at G0/G1 phase of cell cycle, induces apoptosis and suppresses cell migration in CRC cells. 2,6-Dihydroxyacetophenone inhibits xanthine oxidase (XOD) with an IC₅₀ of 1.24 mM. 2,6-dihydroxyacetophenone improves uric acid metabolism in hyperuricemia mice, reduces plasma cholesterol in hypercholesterolemic rats, and inhibits lipid accumulation in HFD-induced obese mice. 2,6-Dihydroxyacetophenone can be used for the study of colorectal cancer (CRC), hyperuricemia and hypercholesterolemia .

HY-N16606

2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone	Drug Derivative NO Synthase	Inflammation/Immunology
2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone (Compound 8) is an Acetophenone (HY-Y0989) derivative found in Acronychia oligophlebia. 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone exhibits anti-inflammatory and antioxidant activities. 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone can inhibit LPS (HY-D1056)-induced NO production (IC₅₀ = 34.5 μM) and scavenge DPPH free radical (SC₅₀ = 0.15 mM). 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone can be used for the research of inflammation .

HY-N8680

12-Hydroxy-2,3-dihydroeuparin	Others	Inflammation/Immunology
12-Hydroxy-2,3-dihydroeuparin (compound 7) is a natural product that can be isolated from the aerial parts of Ophryosporus axilliflorus. 12-Hydroxy-2,3-dihydroeuparin shows extremely anti-inflammatory activity .

HY-W012658R

2-Methylacetophenone (Standard) O-Methylacetophenone (Standard)	Reference Standards Xanthine Oxidase	Metabolic Disease
2-Methylacetophenone (O-Methylacetophenone) (Standard) is the analytical standard of 2-Methylacetophenone (HY-W012658). This product is intended for research and analytical applications. 2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a xanthine dehydrogenase (XDH) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust .

HY-N18314

2,4,6-Trihydroxy-5-methoxyacetophenone	Drug Derivative	Others
2,4,6-Trihydroxy-5-methoxyacetophenone (Compound 56) is an acetophenone derivative that can be isolated from the trunk bark of Antiaris toxicaria .

HY-Y0106R

2,6-Dihydroxyacetophenone (Standard)	Reference Standards mTOR Xanthine Oxidase Apoptosis	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
2,6-Dihydroxyacetophenone (Standard) is the analytical standard of 2,6-Dihydroxyacetophenone (HY-Y0106). This product is intended for research and analytical applications. 2,6-Dihydroxyacetophenone, a polyphenolic derivative of Acetophenone (HY-Y0989), is an orally active mTOR inhibitor. 2,6-Dihydroxyacetophenone shows antioxidant activity. 2,6-Dihydroxyacetophenone inhibits cell growth and proliferation in CRC cells. 2,6-Dihydroxyacetophenone arrests at G0/G1 phase of cell cycle, induces apoptosis and suppresses cell migration in CRC cells. 2,6-Dihydroxyacetophenone inhibits xanthine oxidase (XOD) with an IC₅₀ of 1.24 mM. 2,6-dihydroxyacetophenone improves uric acid metabolism in hyperuricemia mice, reduces plasma cholesterol in hypercholesterolemic rats, and inhibits lipid accumulation in HFD-induced obese mice. 2,6-Dihydroxyacetophenone can be used for the study of colorectal cancer (CRC), hyperuricemia and hypercholesterolemia .

HY-W404362

2,4,6-Trihydroxy-3-prenylacetophenone	Drug Intermediate	Others
2,4,6-Trihydroxy-3-prenylacetophenone (compound 13) is a prenylated acetophenone derivative that can be used as a synthetic intermediate .

Cat. No.	Product Name	Type

HY-N1731

2′-Hydroxy-5′-methoxyacetophenone	Biochemical Assay Reagents
2'-Hydroxy-5'-methoxyacetophenone is an acetophenone derivative with acaricidal activities. 2'-Hydroxy-5'-methoxyacetophenone attenuates the inﬂammatory response via NF-κB signaling pathway. 2'-Hydroxy-5'-methoxyacetophenone exhibits significant inhibitory activity against α-amylase, collagenase and aldose reductase (AR) with IC₅₀s of 0.928, 3.264 and 20.046 μM, highlighting its potential in combating diabetes. 2'-Hydroxy-5'-methoxyacetophenone exhibits anti-ovarian cancer activity .

2′-Hydroxy-5′-methoxyacetophenone

Biochemical Assay Reagents

2'-Hydroxy-5'-methoxyacetophenone is an acetophenone derivative with acaricidal activities. 2'-Hydroxy-5'-methoxyacetophenone attenuates the inﬂammatory response via NF-κB signaling pathway. 2'-Hydroxy-5'-methoxyacetophenone exhibits significant inhibitory activity against α-amylase, collagenase and aldose reductase (AR) with IC₅₀s of 0.928, 3.264 and 20.046 μM, highlighting its potential in combating diabetes. 2'-Hydroxy-5'-methoxyacetophenone exhibits anti-ovarian cancer activity .

2-Methylacetophenone O-Methylacetophenone	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Xanthine Oxidase
2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a xanthine dehydrogenase (XDH) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust .

2,6-Dihydroxyacetophenone	Classification of Application Fields Ketones, Aldehydes, Acids Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	mTOR Xanthine Oxidase Apoptosis
2,6-Dihydroxyacetophenone, a polyphenolic derivative of Acetophenone (HY-Y0989), is an orally active mTOR inhibitor. 2,6-Dihydroxyacetophenone shows antioxidant activity. 2,6-Dihydroxyacetophenone inhibits cell growth and proliferation in CRC cells. 2,6-Dihydroxyacetophenone arrests at G0/G1 phase of cell cycle, induces apoptosis and suppresses cell migration in CRC cells. 2,6-Dihydroxyacetophenone inhibits xanthine oxidase (XOD) with an IC₅₀ of 1.24 mM. 2,6-dihydroxyacetophenone improves uric acid metabolism in hyperuricemia mice, reduces plasma cholesterol in hypercholesterolemic rats, and inhibits lipid accumulation in HFD-induced obese mice. 2,6-Dihydroxyacetophenone can be used for the study of colorectal cancer (CRC), hyperuricemia and hypercholesterolemia .

2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone	Structural Classification Monophenols Rutaceae Phenols Plants Maclurodendron oligophlebium (Merrill) T. G. Hartley Source Classification	Drug Derivative NO Synthase
2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone (Compound 8) is an Acetophenone (HY-Y0989) derivative found in Acronychia oligophlebia. 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone exhibits anti-inflammatory and antioxidant activities. 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone can inhibit LPS (HY-D1056)-induced NO production (IC₅₀ = 34.5 μM) and scavenge DPPH free radical (SC₅₀ = 0.15 mM). 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone can be used for the research of inflammation .

12-Hydroxy-2,3-dihydroeuparin	Classification of Application Fields Ophryosporus axilliflorus Hieron. Phenols Plants Compositae Inflammation/Immunology Disease Research Fields Source Classification	Others
12-Hydroxy-2,3-dihydroeuparin (compound 7) is a natural product that can be isolated from the aerial parts of Ophryosporus axilliflorus. 12-Hydroxy-2,3-dihydroeuparin shows extremely anti-inflammatory activity .

2-Methylacetophenone (Standard) O-Methylacetophenone (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Xanthine Oxidase
2-Methylacetophenone (O-Methylacetophenone) (Standard) is the analytical standard of 2-Methylacetophenone (HY-W012658). This product is intended for research and analytical applications. 2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a xanthine dehydrogenase (XDH) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust .

2,4,6-Trihydroxy-5-methoxyacetophenone	Antiaris toxicaria Lesch. Structural Classification Phenols Polyphenols Plants Moraceae Source Classification	Drug Derivative
2,4,6-Trihydroxy-5-methoxyacetophenone (Compound 56) is an acetophenone derivative that can be isolated from the trunk bark of Antiaris toxicaria .

2,6-Dihydroxyacetophenone (Standard)	Structural Classification Ketones, Aldehydes, Acids Phenols Polyphenols Endogenous metabolite Source Classification	Reference Standards mTOR Xanthine Oxidase Apoptosis
2,6-Dihydroxyacetophenone (Standard) is the analytical standard of 2,6-Dihydroxyacetophenone (HY-Y0106). This product is intended for research and analytical applications. 2,6-Dihydroxyacetophenone, a polyphenolic derivative of Acetophenone (HY-Y0989), is an orally active mTOR inhibitor. 2,6-Dihydroxyacetophenone shows antioxidant activity. 2,6-Dihydroxyacetophenone inhibits cell growth and proliferation in CRC cells. 2,6-Dihydroxyacetophenone arrests at G0/G1 phase of cell cycle, induces apoptosis and suppresses cell migration in CRC cells. 2,6-Dihydroxyacetophenone inhibits xanthine oxidase (XOD) with an IC₅₀ of 1.24 mM. 2,6-dihydroxyacetophenone improves uric acid metabolism in hyperuricemia mice, reduces plasma cholesterol in hypercholesterolemic rats, and inhibits lipid accumulation in HFD-induced obese mice. 2,6-Dihydroxyacetophenone can be used for the study of colorectal cancer (CRC), hyperuricemia and hypercholesterolemia .

2,4,6-Trihydroxy-3-prenylacetophenone	Structural Classification Carlina acaulis L. Phenols Polyphenols Umbelliferae Plants Source Classification	Drug Intermediate
2,4,6-Trihydroxy-3-prenylacetophenone (compound 13) is a prenylated acetophenone derivative that can be used as a synthetic intermediate .

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acetophenone derivative

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