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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
acylase
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "acylase" in MCE Product Catalog:
Cat. No.: HY-E70318
Target:
Domaines de recherche:
Penicillin G acylase (Immobilized) is an immobilized penicillin acylase with improved temperature and pH stability. Penicillin G acylase (Immobilized) has reusable performance and high recovery rates, retaining much of its original activity after 12 cycles. Among them, Penicillin G acylase (Immobilized) can catalyze penicillin G (PG) to generate 6-aminopenicillanic acid (6-APA) and 7-aminodeacetoxycephalosporanic acid, which are key intermediates for β-lactam antibiotics .
Cat. No.: HY-W004114
CAS No.: 68-95-1
Target:
Target:
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Aminoacylase (Acylase I) is a specific N-acetylglutamine metabolic-degrading enzyme. Aminoacylase is a key enzyme in the intracellular amino acid recycling pathway. Aminoacylase has detoxifying properties .
Cat. No.: HY-E70137
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AMG 118 Immobilized cephalosporin C acylase is an enzyme that catalyzes in immobilized form and is generally used in industrial catalytic production of the important pharmaceutical intermediate 7-aminocephalosporanic acid (7-ACA). It contains CPC acylase, a highly specialized beta-lactam acylase or peptidase that cleaves the amide bonds between beta-lactams .
Cat. No.: HY-164170
CAS No.: 2321346-88-5
Synonyms: pm-DAP
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Photocaged DAP (pm-DAP) is a protected version of 2,3-Diaminopropionic acid (DAP) (HY-W013673). Photocaged DAP can produce 2,3-Diaminopropionic acid after photodeprotection. Photocaged DAP can be used as an intermediate to capture biosynthetic acylase .
Cat. No.: HY-178970
HDAC11-IN-4 is a potent and selective HDAC11 inhibitor with an IC50 of 13.49 nM and a Ki of 2.2 nM. HDAC11-IN-4 exhibits extremely high selectivity for HDAC11 over other defatty-acylases such as SIRT2, SIRT3, SIRT6, and HDAC8 (SI >10,000). HDAC11-IN-4 can be used for the research of cancer .
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Lithium citrate is a lithium supplement that reduces excess brain N-acetylaspartate (NAA) in Canavan disease. Canavan disease is an autosomal recessive leukodystrophy caused by mutations in the aspartate acylase (ASPA) gene, which catalyzes the hydrolysis of N-acetylaspartate (NAA) to acetate and aspartate .
Synonyms: L-Dihydroalprenolol
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Domaines de recherche:
(-)-Dihydroalprenolol (L-Dihydroalprenolol) is a β-adrenergic antagonist that inhibits the activity of β-adrenergic receptors. (-)-Dihydroalprenolol can cause desensitization of approximately 60% of β-adrenergic receptor binding sites. (-)-Dihydroalprenolol has also been shown to reduce the binding capacity of specific β-adrenergic ligands. (-)-Dihydroalprenolol may affect the ability to stimulate membrane-bound adenylate acylase .
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ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions .
Cat. No.: HY-E70320
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Cefadroxil acylase (Immobilized) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
Cat. No.: HY-E70322
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Cefaclor acylase (Immobilized) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
Cat. No.: HY-E70323
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Cephalexin acylase (Immobilized) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
Cat. No.: HY-E70324
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Domaines de recherche:
Amoxicillin acylase (Immobilized) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
Cat. No.: HY-P2954
CAS No.: 111174-43-7
Synonyms: Polymyxin acylase
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Polymyxin deacylase (Polymyxin acylase) is an N-myristoyl lyase. Polymyxin deacylase can deacylate polymyxin antibiotics and long-chain fatty acyl groups of proteins and peptides. Polymyxin deacylase exhibits antitumor activity against oral epithelial cancer cells. Polymyxin deacylase can be used in research on oral epithelial cancer and other cancers .
Cat. No.: HY-Y1662
CAS No.: 65979-42-2
Synonyms: E.C. 3.5.1.81; D-Amino acid acylase; N-Acyl-D-amino-acid deacylase
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D-Aminoacylase (E.C. 3.5.1.81) catalyzes the enantioselective hydrolysis of Nacyl-D-amino acids to produce D -amino acids .
Synonyms: pm-DAP TFA
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Domaines de recherche:
Photocaged DAP (pm-DAP) TFA is a protected version of 2,3-Diaminopropionic acid (DAP) (HY-W013673). Photocaged DAP TFA can produce 2,3-Diaminopropionic acid after photodeprotection. Photocaged DAP TFA can be used as an intermediate to capture biosynthetic acylase .
Cat. No.: HY-E70956
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Domaines de recherche:
Polymyxin Acylase, Pseudomonas sp. deacylates polymyxin group antibiotics and long-chain fatty acyl groups of proteins.
Cat. No.: HY-E70321
Target:
Domaines de recherche:
Cefradine acylase (Immobilized) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
Cat. No.: HY-187143
CAS No.: 39066-13-2
4-Chloro-α-propylbenzeneacetonitrile is a PvdQ acylase competitive inhibitor with an IC50 of 5.9 μM. 4-Chloro-α-propylbenzeneacetonitrile binds to the acyl-binding site of PvdQ to block acylase activity. 4-Chloro-α-propylbenzeneacetonitrile can be used for the research of Pseudomonas aeruginosa infection .
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N-(Phenylacetyl)-L-phenylalanine (N-Phenylacetylphenylalanine) is an amino acid analog. N-(Phenylacetyl)-L-phenylalanine is produced via the enantioselective acylation of L-phenylalanine catalyzed by penicillin G acylase from Alcaligenes faecalis. N-(Phenylacetyl)-L-phenylalanine undergoes hydrolysis in aqueous media .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
