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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
40 Results for "
anterior pituitary
" in MedChemExpress (MCE) Product Catalog:
Products (40)
40 Results for "anterior pituitary" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-P74133
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CGA; anterior pituitary Glycoprotein Hormones Common Subunit Alpha; Glycoprotein Hormones, Alpha Polypeptide; Follicle-Stimulating Hormone Alpha Subunit; Glycoprotein Hormones Alpha Chain; Chorionic Gonadotropin, Alpha Polypeptide; GPA1; Follicle-Stimulat
Species:
Human
Source:
HEK293
3
3 Cited Publications
Synonyms: hCG; Chorionic gonadotropic hormone
Target:
3
3 Cited Publications
Cat. No.: HY-P0086
CAS No.: 86784-80-7
Synonyms: Human CRF; Human corticotropin-releasing factor
Target:
Research Areas:
1
Target:
Research Areas:
Metabolic Disease Inflammation/Immunology Endocrinology Cancer
Thyrotropin (TSH, Pretiron) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin prevents Apoptosis. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism .
1
1 Cited Publications
Synonyms: ACTH; Adrenocorticotrophic hormone
Target:
Androgen Receptor Reactive Oxygen Species (ROS) Mitochondrial Metabolism Interleukin Related TNF Receptor
Research Areas:
1
Target:
Research Areas:
(R)-Nimodipine ((R)-BAY-e 9736) is an orally active, blood-brain barrier-permeable L-type calcium channel blocker with an IC50 of 5 nM. (R)-Nimodipine inhibits corticosterone release by blocking calcium channels on the hypothalamic-pituitary-adrenal axis, thereby reversing immobilization stress-induced memory impairment and behavioral abnormalities. (R)-Nimodipine is widely used in studies related to aneurysmal subarachnoid hemorrhage, cerebral ischemia, epilepsy, age-related degenerative neurological diseases, and alcohol intoxication .
1
1 Cited Publications
Cat. No.: HY-106373A
Purity: 99.85%
Synonyms: ACTH TFA; Adrenocorticotrophic hormone TFA
Target:
Androgen Receptor Reactive Oxygen Species (ROS) Mitochondrial Metabolism Interleukin Related TNF Receptor
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P703702
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CGA; anterior pituitary Glycoprotein Hormones Common Subunit Alpha; Glycoprotein Hormones, Alpha Polypeptide; Follicle-Stimulating Hormone Alpha Subunit; Glycoprotein Hormones Alpha Chain; Chorionic Gonadotropin, Alpha Polypeptide; GPA1; Follicle-Stimulat
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70237
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CGA; anterior pituitary Glycoprotein Hormones Common Subunit Alpha; Glycoprotein Hormones, Alpha Polypeptide; Follicle-Stimulating Hormone Alpha Subunit; Glycoprotein Hormones Alpha Chain; Chorionic Gonadotropin, Alpha Polypeptide; GPA1; Follicle-Stimulat
Species:
Human
Source:
HEK293
Category:
Target:
Cat. No.: HY-P2618
CAS No.: 2237216-30-5
Target:
Research Areas:
Synonyms: 5,6-EET; (±)5,6-EpETrE
Target:
Research Areas:
5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 (IC50=0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2.
Cat. No.: HY-137199
CAS No.: 65147-21-9
Target:
Research Areas:
Cat. No.: HY-P0246
CAS No.: 72093-21-1
Target:
Cat. No.: HY-P0089A
Synonyms: Growth Hormone Releasing Factor human TFA; Somatorelin (1-44) amide (human) TFA
Target:
Research Areas:
Cat. No.: HY-P1174
CAS No.: 100111-07-7
Target:
Research Areas:
Cat. No.: HY-P0089
CAS No.: 83930-13-6
Synonyms: Growth Hormone Releasing Factor human; Somatorelin (1-44) amide (human)
Target:
Research Areas:
Cat. No.: HY-P4413
CAS No.: 1815617-95-8
Target:
Research Areas:
Cat. No.: HY-P3567
CAS No.: 159600-82-5
Target:
Research Areas:
Cat. No.: HY-P1905
CAS No.: 47922-48-5
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
