2237216-30-5
2237216-30-5
Chemical Structure
Pro-Phe-Arg-AMC acetate
- CAS. Nr.: 2237216-30-5
- Formula:C32H41N7O7
- Molecular Weight:635.71
IUPAC Name: (S)-N-((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide acetate
InChIKey: LBCXUFVFWVGGJF-NYTZCTPBSA-N
SMILES: CC(C(C(O1)=C2)=CC=C2NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H]3CCCN3)=O)CC4=CC=CC=C4)=O)=O)=CC1=O.CC(O)=O
Biological Activity: Pro-Phe-Arg-AMC acetate is a substrate for human glandular kallikrein 2. Pro-Phe-Arg-AMC acetate can be used for the quantitative detection of enzyme activity[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Pro-Phe-Arg-AMC acetate | 99.84% | Pro-Phe-Arg-AMC acetate is a substrate for human glandular kallikrein 2. Pro-Phe-Arg-AMC acetate can be used for the quantitative detection of enzyme activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.96
HY-137199Pro-Phe-Arg-AMC -
Similarity Score 0.77
HY-W344383Boc-Phe-Ser-Arg-AMC -
Similarity Score 0.76
HY-P4360Suc-Ala-Phe-Lys-AMC -
Similarity Score 0.76
HY-P1759AN-CBZ-Phe-Arg-AMC hydrochloride -
Similarity Score 0.76
HY-P1759N-CBZ-Phe-Arg-AMC -
Similarity Score 0.75
HY-P10355Succinimide-AFK-AMC acetate -
Similarity Score 0.75
HY-P4339Ala-Phe-Lys-AMC -
Similarity Score 0.75
HY-D1634Bz-FVR-AMC -
Similarity Score 0.74
HY-P4345Pro-Arg-AMC -
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References
- [1]. Ohyama K, et al. Electrochemical Detection of Kallikrein Using a p -Methoxyaniline-conjugated Tripeptide towards Simple Diagnosis of Primary Aldosteronism. Chem. Lett. 2019 Nov 6;49(1):57-59.
- [2]. Lövgren J, et al. Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors. Eur J Biochem. 1999 Jun;262(3):781-9. [Content Brief]
