2. Others
  3. Biochemical Assay Reagents
  4. Pro-Phe-Arg-AMC

Pro-Phe-Arg-AMC is a synthetic peptide substrate of Cysteine peptidases (CPs).

For research use only. We do not sell to patients.

Pro-Phe-Arg-AMC

Pro-Phe-Arg-AMC Chemical Structure

CAS No. : 65147-21-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
1 mg In-stock
5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Pro-Phe-Arg-AMC:

Pro-Phe-Arg-AMC Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Pro-Phe-Arg-AMC is a synthetic peptide substrate of Cysteine peptidases (CPs)[1].

Molecular Weight

575.66

Formula

C30H37N7O5
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Pro-Phe-Arg-AMC
Sequence Shortening

PFR-AMC
SMILES

CC(C(C(O1)=C2)=CC=C2NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H]3CCCN3)=O)CC4=CC=CC=C4)=O)=O)=CC1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (173.71 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7371 mL 8.6857 mL 17.3714 mL
5 mM 0.3474 mL 1.7371 mL 3.4743 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7371 mL 8.6857 mL 17.3714 mL 43.4284 mL
5 mM 0.3474 mL 1.7371 mL 3.4743 mL 8.6857 mL
10 mM 0.1737 mL 0.8686 mL 1.7371 mL 4.3428 mL
15 mM 0.1158 mL 0.5790 mL 1.1581 mL 2.8952 mL
20 mM 0.0869 mL 0.4343 mL 0.8686 mL 2.1714 mL
25 mM 0.0695 mL 0.3474 mL 0.6949 mL 1.7371 mL
30 mM 0.0579 mL 0.2895 mL 0.5790 mL 1.4476 mL
40 mM 0.0434 mL 0.2171 mL 0.4343 mL 1.0857 mL
50 mM 0.0347 mL 0.1737 mL 0.3474 mL 0.8686 mL
60 mM 0.0290 mL 0.1448 mL 0.2895 mL 0.7238 mL
80 mM 0.0217 mL 0.1086 mL 0.2171 mL 0.5429 mL
100 mM 0.0174 mL 0.0869 mL 0.1737 mL 0.4343 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Pro-Phe-Arg-AMC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pro-Phe-Arg-AMC65147-21-9Biochemical Assay Reagentspeptide substrateCysteine peptidasesInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Pro-Phe-Arg-AMC
Cat. No.:
HY-137199
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (254 KB) Français - FR (254 KB) Deutsch - DE (254 KB) Norwegian - NO (254 KB) Español - ES (254 KB) Swedish - SV (254 KB) Italian - IT (254 KB) Korean - KR (254 KB) Portuguese - PT (254 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.