69 Results for "

antioxidative effects

" in MedChemExpress (MCE) Product Catalog:
Products (69)

69 Results for "antioxidative effects" in MCE Product Catalog:

19
Matrine
Matrine
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19 Publications Verification
Cat. No.: HY-N0164
CAS No.: 519-02-8
Synonyms: Matridin-15-one; Vegard; α-Matrine
Category:  

Plants Sophora flavescens Aiton Biological Pesticide Research Agricultural Research Alkaloids Piperidine Alkaloids Leguminosae Disease Research Fields Inflammation/Immunology Cancer

Target:  

PINK1/Parkin Opioid Receptor Autophagy Mitophagy Ferroptosis Apoptosis

Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) .
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19
Gastrodin
Gastrodin
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19 Publications Verification
Cat. No.: HY-N0115
CAS No.: 62499-27-8
Synonyms: Gastrodine
Category:  

Natural Products Neurological Disease Gastrodia elata Bl. Anti-aging Orchidaceae Phenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis Ferroptosis

Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H2O2-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia .
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10
Benzbromarone
Benzbromarone
0 Images
10 Cited Publications
Cat. No.: HY-B1135
CAS No.: 3562-84-3
Target:  

Xanthine Oxidase Apoptosis Interleukin Related Keap1-Nrf2 SOD Caspase Bcl-2 Family NF-κB JNK HSP

Research Areas:  

Metabolic Disease

Benzbromarone is an orally active anti-gout agent. Benzbromarone has anti-infammatory, anti-oxidative stress and nephroprotective effects. Benzbromarone can be used for the research of hyperuricemia and gout .
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10
3,4-Dicaffeoylquinic acid
3,4-Dicaffeoylquinic acid
0 Images
10 Cited Publications
Cat. No.: HY-N0057
CAS No.: 14534-61-3
Synonyms: 3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B
Category:  

Infection Caprifoliaceae Ketones, Aldehydes, Acids Phenols Polyphenols Plants Endogenous metabolite Disease Research Fields

Target:  

Free Radical Scavengers Glycosidase Influenza Virus Apoptosis Endogenous Metabolite

3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .
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8
Afzelin
Afzelin
0 Images
8 Cited Publications
Cat. No.: HY-N1441
CAS No.: 482-39-3
Synonyms: Kaempferol-3-O-rhamnoside
Category:  

Flavonols Saururaceae Flavonoids  Houttuynia cordata Thunb. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Mitochondrial Metabolism PTEN Autophagy Bacterial

Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin .
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7
Farrerol
Farrerol
0 Images
7 Cited Publications
Cat. No.: HY-N0344
CAS No.: 24211-30-1
Synonyms: (-)-Farrerol
Category:  

Neurological Disease  Rhododendron dauricum Linn. Plants Flavonoids Flavonones Phenols Polyphenols Ericaceae Disease Research Fields Inflammation/Immunology

Target:  

Others

Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .
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6
MnTBAP chloride
MnTBAP chloride
0 Images
6 Cited Publications
Cat. No.: HY-126397
CAS No.: 55266-18-7
Purity:  ≥98.0%
Target:  

NF-κB

Research Areas:  

Inflammation/Immunology

MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research .
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6
S-1-Propenyl-L-cysteine
S-1-Propenyl-L-cysteine
0 Images
6 Cited Publications
Cat. No.: HY-111827
CAS No.: 52438-09-2
Purity:  99.91%
Category:  

Cardiovascular Disease Liliaceae Ketones, Aldehydes, Acids  Allium sativum Linn. Plants Disease Research Fields

Target:  

Histamine Receptor

S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model . S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway . S-1-Propenyl-L-cysteine is orally active.
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5
Mogroside V
Mogroside V
0 Images
5 Cited Publications
Cat. No.: HY-N0502
CAS No.: 88901-36-4
Category:  

Triterpenes Terpenoids Cucurbitaceae Metabolic Disease Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Sweeteners Food Research

Target:  

Reactive Oxygen Species (ROS)

Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
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5
Calycosin-7-O-β-D-glucoside
Calycosin-7-O-β-D-glucoside
0 Images
5 Cited Publications
Cat. No.: HY-N0520
CAS No.: 20633-67-4
Synonyms: Calycosin-7-glucoside
Category:  

Flavonoids Monophenols Leguminosae Other Diseases Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Phenols Plants Disease Research Fields Isoflavones

Target:  

Reactive Oxygen Species (ROS)

Calycosin-7-O-β-D-glucoside is an isoflavone isolated from Astragali Radix. Calycosin-7-O-β-D-glucoside has variety of biological activities, such as neuroprotective, cardioprotection, anti-inflammation, and antioxidative stress effects .
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5
Esculin sesquihydrate
Esculin sesquihydrate
0 Images
5 Cited Publications
Cat. No.: HY-W166297
CAS No.: 66778-17-4
Target:  

p38 MAPK

Research Areas:  

Cancer

Esculin sesquihydrate, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin sesquihydrate ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti?oxidative stress and anti?inflammatory effects, via the MAPK signaling pathway .
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4
Tyrosol
Tyrosol
0 Images
4 Cited Publications
Cat. No.: HY-N0474
CAS No.: 501-94-0
Category:  

Anti-aging Plants Burseraceae Endogenous metabolite Microorganisms Monophenols Canarium album (Lour.) Rauesch. Phenols Disease Research Fields Inflammation/Immunology

Target:  

NF-κB Endogenous Metabolite

Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects .
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4
Gentiopicroside
Gentiopicroside
0 Images
4 Cited Publications
Cat. No.: HY-N0494
CAS No.: 20831-76-9
Synonyms: Gentiopicrin
Category:  

Gentiana scabra Bunge Iridoids Terpenoids Gentianaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

Cytochrome P450 HCV

Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
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3
Ergosterol
Ergosterol
0 Images
3 Cited Publications
Cat. No.: HY-N0181
CAS No.: 57-87-4
Category:  

Microorganisms Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids

Target:  

Endogenous Metabolite

Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects.
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3
Marein
Marein
0 Images
3 Cited Publications
Cat. No.: HY-N7676
CAS No.: 535-96-6
Category:  

Cardiovascular Disease other families Flavonoids Chalcones Neurological Disease Phenols Polyphenols Plants Disease Research Fields

Target:  

AMPK HDAC

Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 μM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects .
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3
Tubuloside B
Tubuloside B
0 Images
3 Cited Publications
Cat. No.: HY-N7637
CAS No.: 112516-04-8
Category:  

Cistanche salsa (C. A. Mey.) G. Beck Orobanchaceae Other Phenylpropanoids Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Cancer

Target:  

Apoptosis

Tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, inhibits TNFα-induced apoptosis. Tubuloside B possesses antioxidative effects .
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2
Isoliquiritin
Isoliquiritin
0 Images
2 Cited Publications
Cat. No.: HY-N0765
CAS No.: 5041-81-6
Category:  

Neurological Disease Plants Flavonoids Chalcones Leguminosae Phenols Polyphenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

Fungal

Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity .
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2
24-Methylenecholesterol
24-Methylenecholesterol
0 Images
2 Cited Publications
Cat. No.: HY-133968
CAS No.: 474-63-5
Purity:  99.48%
Synonyms: Ostreasterol
Category:  

other families Animals Anti-aging Marine natural products Other marine organisms Plants Disease Research Fields Inflammation/Immunology Steroids

Target:  

Acyltransferase Reactive Oxygen Species (ROS)

24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .
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2
Amarogentin
Amarogentin
0 Images
2 Cited Publications
Cat. No.: HY-N2447
CAS No.: 21018-84-8
Category:  

Gentiana scabra Bunge Iridoids Terpenoids Gentianaceae Metabolic Disease Phenols Polyphenols Plants Disease Research Fields

Target:  

AMPK Apoptosis

Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .
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2
Terlipressin diacetate
Terlipressin diacetate
0 Images
2 Cited Publications
Cat. No.: HY-12554A
CAS No.: 1884420-36-3
Purity:  99.76%
Target:  

Vasopressin Receptor

Research Areas:  

Cardiovascular Disease Inflammation/Immunology Endocrinology

Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .
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