2. MAPK/ERK Pathway
  3. p38 MAPK
  4. Esculin sesquihydrate

Esculin sesquihydrate, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin sesquihydrate ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti?oxidative stress and anti?inflammatory effects, via the MAPK signaling pathway.

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Esculin sesquihydrate Chemical Structure

Esculin sesquihydrate Chemical Structure

CAS No. : 66778-17-4

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Description

Esculin sesquihydrate, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin sesquihydrate ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti?oxidative stress and anti?inflammatory effects, via the MAPK signaling pathway[1][2].

Molecular Weight

367.31

Formula

C15H16O9.3/2H2O
CAS No.
SMILES

O=C1C=CC2=CC(O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)=C(O)C=C2O1.O.[3/2]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Esculin sesquihydrate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Esculin sesquihydrate66778-17-4p38 MAPKcognitivediabeticanti?oxidativeanti?inflammatoryInhibitorinhibitorinhibit

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