28 Results for "

aporphine

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "aporphine" in MCE Product Catalog:

1
(+)-Magnoflorine chloride
(+)-Magnoflorine chloride
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1 Cited Publications
Cat. No.: HY-N0535
CAS No.: 6681-18-1
Synonyms: Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride
Category:  

Metabolic Disease Plants Aristolochiaceae Infection Alkaloids Piperidine Alkaloids other families Aristolochia debilis Sieb. et Zucc. Phenols Polyphenols Disease Research Fields

Target:  

Fungal Autophagy Apoptosis PINK1/Parkin NOD-like Receptor (NLR) Caspase JNK NF-κB Sirtuin AMPK Reactive Oxygen Species (ROS)

(+)-Magnoflorine (α-Magnoflorine) chloride is an orally active aporphine alkaloid with multiple biological activities. (+)-Magnoflorine chloride promotes Parkin/PINK1-mediated mitochondrial autophagy, inhibits the activation of NLRP3/Caspase-1 pathway, regulates the intestinal microbiota, and exhibits significant anti-inflammatory and immunomodulatory activities. (+)-Magnoflorine chloride inhibits JNK and TLR4/NF-κB signaling pathways, activates Sirt1/AMPK pathway, alleviates neuronal oxidative stress and apoptosis. Magnoflorine chloride upregulates miR-410-3p, inhibits HMGB1/NF-κB pathway, and has anti-tumor activity. (+)-Magnoflorine chloride also has significant antifungal activity .
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(+)-Magnoflorine iodide
(+)-Magnoflorine iodide
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1 Cited Publications
Cat. No.: HY-N0334A
CAS No.: 4277-43-4
Synonyms: Magnoflorine iodide; α-Magnoflorine iodide; Thalictrine iodide
Category:  

Alkaloids Magnoliaceae Metabolic Disease Phenols Polyphenols Magnolia Liliflora Desr. Plants Disease Research Fields Isoquinoline Alkaloids

Target:  

Fungal Autophagy Apoptosis PINK1/Parkin NOD-like Receptor (NLR) Caspase JNK NF-κB Sirtuin AMPK Reactive Oxygen Species (ROS)

(+)-Magnoflorine (α-Magnoflorine) iodide is an orally active aporphine alkaloid with multiple biological activities. (+)-Magnoflorine iodide promotes Parkin/PINK1 -mediated mitochondrial autophagy, inhibits the activation of NLRP3/Caspase-1 pathway, regulates the intestinal microbiota, and exhibits significant anti-inflammatory and immunomodulatory activities. (+)-Magnoflorine iodide inhibits JNK and TLR4/NF-κB signaling pathways, activates Sirt1/AMPK pathway, alleviates neuronal oxidative stress and apoptosis. Magnoflorine upregulates miR-410-3p, inhibits HMGB1/NF-κB pathway, and has anti-tumor activity. (+)-Magnoflorine iodide also has significant antifungal activity .
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(+)-Magnoflorine
(+)-Magnoflorine
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Cat. No.: HY-N0334
CAS No.: 2141-09-5
Synonyms: Magnoflorine; α-Magnoflorine; Thalictrine
Category:  

Alkaloids Ranunculaceae Coptis chinensis Franch. Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Isoquinoline Alkaloids

Target:  

Fungal Autophagy Apoptosis PINK1/Parkin NOD-like Receptor (NLR) Caspase JNK NF-κB Sirtuin AMPK Reactive Oxygen Species (ROS)

(+)-Magnoflorine (α-Magnoflorine) is an orally active aporphine alkaloid with multiple biological activities. (+)-Magnoflorine promotes Parkin/PINK1 -mediated mitochondrial autophagy, inhibits the activation of NLRP3/Caspase-1 pathway, regulates the intestinal microbiota, and exhibits significant anti-inflammatory and immunomodulatory activities. (+)-Magnoflorine inhibits JNK and TLR4/NF-κB signaling pathways, activates Sirt1/AMPK pathway, alleviates neuronal oxidative stress and apoptosis. Magnoflorine upregulates miR-410-3p, inhibits HMGB1/NF-κB pathway, and has anti-tumor activity. (+)-Magnoflorine also has significant antifungal activity .
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Liriodenine
Liriodenine
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Cat. No.: HY-N3376
CAS No.: 475-75-2
Synonyms: Spermatheridine; VLT045
Category:  

Alkaloids Magnoliaceae Pyridine Alkaloids Plants  Liriodendron chinense (Hemsl.) Sarg. Disease Research Fields Cancer

Target:  

Apoptosis

Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant?Mitrephora sirikitiae?and has anti-cancer activities . Liriodenine induces cell apoptosis, activates the intrinsic pathway by induction of caspase-3 and caspase-9 .
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O-Nornuciferine
O-Nornuciferine
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Cat. No.: HY-N7511
CAS No.: 3153-55-7
Category:  

Alkaloids other families Monophenols Metabolic Disease Phenols Plants Disease Research Fields Isoquinoline Alkaloids

Target:  

Potassium Channel Endogenous Metabolite

O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor .
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Asimilobine
Asimilobine
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Cat. No.: HY-N7512
CAS No.: 6871-21-2
Category:  

Infection Alkaloids Monophenols Phenols Nelumbo nucifera Gaertn. Plants Disease Research Fields Isoquinoline Alkaloids Nymphaeaceae

Target:  

Dopamine Receptor 5-HT Receptor Parasite

Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. Asimilobine is a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist. Asimilobine shows an antimalarial and anti-cancer activity .
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Bulbocapnine hydrochloride
Bulbocapnine hydrochloride
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Cat. No.: HY-W436270
CAS No.: 632-47-3
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease Inflammation/Immunology

Bulbocapnine hydrochloride, an aporphine alkaloid, is a dopamine receptor inhibitor. Bulbocapnine hydrochloride inhibits dopamine synthesis. Bulbocapnine hydrochloride also has neuroleptic-like, anticonvulsant and antinociceptive effects .
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Boldine (Standard)
Boldine (Standard)
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Cat. No.: HY-N6973R
CAS No.: 476-70-0
Category:  

Alkaloids Phenols Plants Lauraceae Disease Research Fields Inflammation/Immunology  Litsea cubeba (Lour.) Pers.

Target:  

Reference Standards RANKL/RANK

Boldine (Standard) is the analytical standard of Boldine. This product is intended for research and analytical applications. Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis .
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(+) N-Methylcorydine
(+) N-Methylcorydine
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Cat. No.: HY-N11090
CAS No.: 7224-60-4
Category:  

Alkaloids Piperidine Alkaloids Rutaceae Plants

Target:  

Others

(+) N-Methylcorydine is an aporphine alkaloid .
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Cassyfiline
Cassyfiline
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Cat. No.: HY-N3547
CAS No.: 4030-51-7
Synonyms: Cassythine
Category:  

Alkaloids Other Alkaloids Cassytha filiformis L. Plants Lauraceae

Target:  

Others

Cassyfiline (Cassythine) is an aporphine alkaloid. Cassyfiline has potent vasorelaxing effects on precontracted rat aortic preparations with an IC50 of 0.09 μM .
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Norisocorydine
Norisocorydine
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Cat. No.: HY-N15703
CAS No.: 475-70-7
Synonyms: (+)-Norisocorydine
Category:  

Alkaloids Microorganisms Unonopsis stipitata Diels Plants Annonaceae Isoquinoline Alkaloids

Target:  

Free Radical Scavengers

Norisocorydine ((+)-Norisocorydine) is an aporphine alkaloid with antinociceptive and radical scavenging effects. Norisocorydine shows a SC50 of 14.1 μg/mL in DPPH radical scavenging test. Norisocorydine exhibits antinociceptive ability in mice .
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(-)-Dicentrine
(-)-Dicentrine
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Cat. No.: HY-N2105
CAS No.: 28832-07-7
Synonyms: L-Dicentrine
Category:  

Alkaloids Aporphine Alkaloids Plants Menispermaceae Stephania sinica Diels

Target:  

Fungal Bacterial

(-)-Dicentrine is an aporphine alkaloid that can be isolated from the stem bark of Talauma arcabucoana. (-)-Dicentrine shows moderate growth inhibition against Staphylococcus aureus and Candida albicans .
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Corytuberine
Corytuberine
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Cat. No.: HY-N2570
CAS No.: 517-56-6
Category:  

Alkaloids Piperidine Alkaloids Dicranostigma leptopodum (Maxim.) Fedde Plants Disease Research Fields Papaveraceae Cancer

Target:  

Others

Corytuberine is an aporphine alkaloid found in Dicranostigma leptopodum. Corytuberine displays cytotoxicity against SMMC-7721 tumor cells .
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Stephanine
Stephanine
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Cat. No.: HY-N1219
CAS No.: 517-63-5
Synonyms: (-)-Stephanine; l-Stephanine
Category:  

Alkaloids Piperidine Alkaloids Plants Menispermaceae Stephania japonica (Thunb.) Miers

Target:  

Apoptosis Parasite

Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer .
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Oxocrebanine
Oxocrebanine
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Cat. No.: HY-N9356
CAS No.: 38826-42-5
Category:  

Alkaloids Other Diseases Plants Annonaceae Disease Research Fields Isoquinoline Alkaloids Fissistigma poilanei (Ast) Tsiang et P. T. Li

Target:  

Others

Oxocrebanine, an aporphine alkaloid, can be found in Fissistigma poilanei (Annonaceae) .
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(+)-N-Formylnorglaucine
(+)-N-Formylnorglaucine
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Cat. No.: HY-N9355
CAS No.: 371196-16-6
Category:  

Alkaloids other families Other Diseases Plants Disease Research Fields Isoquinoline Alkaloids

Target:  

Others

(+)-N-Formylnorglaucine is an aporphine alkaloid isolated from the leaves of Unonopsis stipitata. (+)-N-Formylnorglaucine contains a formyl group linked to the heterocyclic nitrogen .
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(+)-Magnoflorine chloride (Standard)
(+)-Magnoflorine chloride (Standard)
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Cat. No.: HY-N0535R
CAS No.: 6681-18-1
Synonyms: Magnoflorine chloride (Standard); α-Magnoflorine chloride (Standard); Thalictrine chloride (Standard)
Category:  

Alkaloids Piperidine Alkaloids other families Aristolochia debilis Sieb. et Zucc. Phenols Polyphenols Plants Aristolochiaceae

Target:  

Reference Standards Fungal

(+)-Magnoflorine (chloride) (Standard) is the analytical standard of (+)-Magnoflorine (chloride). This product is intended for research and analytical applications. Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm . Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity .
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Norcorydine
Norcorydine
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Cat. No.: HY-N15699
CAS No.: 26931-78-2
Category:  

Alkaloids Annona salzmannii A.DC. Quinoline Alkaloids Plants Annonaceae

Target:  

Biochemical Assay Reagents

Norcorydine is a aporphine alkaloid that can be extracted from the leaves of Annona salzmannii .
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O-Methylcassythine
O-Methylcassythine
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Cat. No.: HY-N13714
CAS No.: 3984-10-9
Category:  

Alkaloids Other Alkaloids Cassytha filiformis L. Plants Lauraceae

Target:  

Endogenous Metabolite

O-Methylcassythine is an aporphine alkaloid, that can be isolated from Cassytha filiformis. O-Methylcassythine exhibits vasodilator activity .
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Dehydrodicentrine
Dehydrodicentrine
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Cat. No.: HY-N2034
CAS No.: 19843-03-9
Category:  

Alkaloids Piperidine Alkaloids Stephania epigaea Lo Plants Menispermaceae

Target:  

Cholinesterase (ChE)

Dehydrodicentrine is an aporphine alkaloid can be isolated from the root of S. epigaea and has inhibitory effect on acetylcholinesterase (AChE) with an IC50 value of 2.98 μM .
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