1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. O-Nornuciferine

O-Nornuciferine 

Cat. No.: HY-N7511
Handling Instructions

O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor.

For research use only. We do not sell to patients.

O-Nornuciferine Chemical Structure

O-Nornuciferine Chemical Structure

CAS No. : 3153-55-7

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Description

O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].

In Vitro

O-Nornuciferine has an IC50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells[1].
O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids[1].

Molecular Weight

281.35

Formula

C₁₈H₁₉NO₂

CAS No.

3153-55-7

SMILES

OC1=C(OC)C2=C3C(CCN(C)[[email protected]]3([H])CC4=CC=CC=C24)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

O-NornuciferinePotassium ChannelKcsAInhibitorinhibitorinhibit

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