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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
avian influenza virus
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "avian influenza virus" in MCE Product Catalog:
Synonyms: TG-1000
Research Areas:
Pixavir marboxilo (TG-1000) is an orally active prodrug of TG-0527 and an analog of Baloxavir marboxil (HY-109025). Pixavir marboxilo undergoes conversion to its active metabolite and inhibits the cap‑dependent endonuclease of Influenza Virus, reduces pulmonary viral titers, and suppresses the proliferation of influenza A, influenza B, H7N9 avian influenza, and neuraminidase‑resistant strains. Pixavir marboxilo can be used in influenza-related research .
Cat. No.: HY-164390
CAS No.: 64364-50-7
Synonyms: Neu5Acα2-6Galβ1-4GlcNAc
Target:
6′SLN is a cancer-related extracellular vesicle (EVs) surface glycan that serves as a key form of protein glycosylation in EVs. 6′SLN is also a sialic acid derivative that can interact with hemagglutinins (HAs) from human and avian influenza virus strains, making it useful for research into anti-influenza drugs .
Cat. No.: HY-130178
CAS No.: 1210501-46-4
Target:
Research Areas:
CL-385319 is an N-substituted piperidine compound with inhibitory activity against H5N1 avian influenza A virus infection. CL-385319 exhibited an IC50 of 27.03±2.54 μM against infection of highly pathogenic H5N1 virus in Madin-Darby canine kidney cells (MDCK). CL-385319 had low cytotoxicity with a CC50 of 1.48 mM and was able to inhibit the entry of pseudoviruses carrying H5N1 strains from different sources, but had no inhibitory effect on the entry of VSV-G pseudotyped particles. Pseudoviruses with the M24A mutation in HA1 or the F110S mutation in HA2 were resistant to CL-385319, indicating that these two residues in the cavity region may be critical for the binding of CL-385319 .
Target:
Research Areas:
MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains .
Cat. No.: HY-177637
Target:
Research Areas:
H5N1 aptamer sodium is a DNA aptamer targeted to H5N1 Avian Influenza Virus.
Cat. No.: HY-144668
CAS No.: 3035088-22-0
Target:
Research Areas:
RdRP-IN-4 (compound 11q), an aryl benzoyl hydrazide analog, is an orally active influenza A virus RNA-dependent RNA polymerase (RdRp) inhibitor by interacting with the PB1 subunit. RdRP-IN-4 exhibits potent inhibitory activity against the avian H5N1 flu strain with an EC50 of 18 nM in MDCK cells. RdRP-IN-4 displays excellent potency against the the H1N1 (A/PR/8/34) Flu A strain and Flu B strain (B/Lee/1940) with EC50 values of 53 nM and 20 nM, respectively. RdRP-IN-4 significantly inhibits the expression level of viral nucleoprotein (NP) in a dose-dependent manner. RdRP-IN-4 exhibits significant antiviral activity in infected mice .
Cat. No.: HY-180408
CAS No.: 90803-80-8
Target:
Research Areas:
Platyphylloside is an anti-virus agent that can be isolated from the bark of Alnus japonica. Platyphylloside exhibits activity against H9N2 avian influenza virus. Platyphylloside can be used for the research of influenza .
Cat. No.: HY-17677
CAS No.: 445032-93-9
Target:
Research Areas:
Antiviral agent 78 (Compound 27) is an antiviral agent. Antiviral agent 78 shows IC50 values of 11.22, 78.54 and 71.49 μM against 2019-nCoV, Ebola virus replicon and avian influenza virus A/Guangzhou/99. Antiviral agent 78 can be used for research of virus infection .
Cat. No.: HY-P992080
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
