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carotenoid biosynthesis

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By Targets:	Acetolactate Synthase (ALS) (1) Apoptosis (1) Biochemical Assay Reagents (2) Calcium Channel (1) Cytochrome P450 (1) Drug Derivative (2) Drug Intermediate (1) Drug Isomer (1) Environmental Pollutants (3) Herbicide (7) HPPD (1) Isotope-Labeled Compounds (1) p38 MAPK (1) PI3K (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2)
By Research Areas:	Inflammation/Immunology (1) Metabolic Disease (2)

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W040206

Diflufenican	Environmental Pollutants Acetolactate Synthase (ALS) Herbicide	Others
Diflufenican is a Herbicide. Diflufenican inhibits phytoene desaturase (PDS) in the carotenoid synthesis pathway. Diflufenican suppresses the production of PDS, blocks carotenoid biosynthesis, thereby inducing chlorophyll destruction and cell membrane rupture, and ultimately causes the death of broadleaf weeds. The combination of Diflufenican and Flufenacet can be used to control Lolium rigidum populations resistant to ALS/ACCase .

HY-W040194

Clomazone	Environmental Pollutants Herbicide	Metabolic Disease
Clomazone is a broad spectrum herbicide, mainly used to control annual broadleaf weeds and grass weeds in various crops such as rice, soybeans, and peanuts. Clomazone inhibits carotenoid biosynthesis, and treated plants show typical "albinism" symptoms due to the destruction of chloroplast membrane structure leading to chlorophyll degradation. Clomazone exhibits multiple toxic effects on non-target organisms, including aquatic lethality, developmental malformations, liver damage, mitochondrial dysfunction, and hematotoxicity .

HY-114849

Norflurazon SAN 9789	Environmental Pollutants Herbicide	Others
Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

HY-W740803

15-cis-Phytofluene (15Z)-Phytofluene	Drug Intermediate Drug Isomer	Others
15-cis-Phytofluene is a cis-isomer of Phytofluene. 15-cis-Phytofluene is an acyclic carotenoid. 15-cis-Phytofluene acts as a biosynthetic intermediate in carotenoid biosynthesis .

HY-W750692

β-Citraurin	Drug Derivative	Others
β-Citraurin is a carotenoid. Jasmonates induce β-Citraurin biosynthesis in citrus by activating a CsMPK6-CsMYC2 cascade, thereby affecting fruit coloration .

HY-W711035

Picolinafen AC 900001	p38 MAPK PI3K Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Cytochrome P450	Inflammation/Immunology
Picolinafen is a pyridine-class herbicide that acts as a phytoene desaturase (PDS) inhibitor. Picolinafen effectively controls broadleaf weeds and disrupts carotenoid biosynthesis. Picolinafen exhibits cytotoxicity to porcine trophectoderm (pTr) and luminal epithelial (pLE) cells. Picolinafen induces (ROS accumulation, calcium depletion, and activates (MAPK and PI3K signaling pathways, leading to decreased cell viability, increased apoptosis, impaired migration, and altered expression of implantation-related genes. Picolinafen has an LD₅₀ value of 2.7 mg/kg in mammals and 7 μg/L in fish. Picolinafen exhibits toxic effects during zebrafish embryogenesis ^[1][2].

HY-114849R

Norflurazon (Standard) SAN 9789 (Standard)	Herbicide Reference Standards	Others
Norflurazon (Standard) is the analytical standard of Norflurazon. This product is intended for research and analytical applications. Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

HY-W778236

Norflurazon-13C,d3 SAN 9789-¹³C,d₃	Isotope-Labeled Compounds Herbicide	Others
Norflurazon- ¹³C,d₃ (SAN 9789- ¹³C,d₃) is the deuterium and ¹³C-labeled Norflurazon (HY-114849). Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

HY-W040194R

Clomazone (Standard)	Herbicide Reference Standards	Metabolic Disease
Clomazone (Standard) is the analytical standard of Clomazone (HY-W040194). This product is intended for research and analytical applications. Clomazone is a broad spectrum herbicide, mainly used to control annual broadleaf weeds and grass weeds in various crops such as rice, soybeans, and peanuts. Clomazone inhibits carotenoid biosynthesis, and treated plants show typical "albinism" symptoms due to the destruction of chloroplast membrane structure leading to chlorophyll degradation. Clomazone exhibits multiple toxic effects on non-target organisms, including aquatic lethality, developmental malformations, liver damage, mitochondrial dysfunction, and hematotoxicity.

HY-W727532

Fenpyrazone	HPPD Herbicide	Others
Fenpyrazone is a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor as well as a post-emergence herbicide. By inhibiting the activity of HPPD, Fenpyrazone indirectly blocks carotenoid biosynthesis in plants, causing bleaching of new tissues in sensitive plants, followed by necrosis and eventual death. Fenpyrazone is used in studies on controlling annual monocotyledonous and dicotyledonous weeds in summer maize fields .

HY-W750723

Rubixanthin	Drug Derivative	Others
Rubixanthin, a carotenoid, is mainly derived from the biosynthesis process of carotenoids in the Flavobacterium strain R-1519 .

HY-E71192

15-cis-Phytoene desaturase	Biochemical Assay Reagents	Others
15-cis-Phytoene desaturase (EC 1.3.5.5) is involved in carotenoid biosynthesis in plants and cyanobacteria.

HY-E71348

ζ-Carotene isomerase	Biochemical Assay Reagents	Others
ζ-Carotene isomerase (EC 5.2.1.12) catalyses the cis-trans isomerization of the 15-15' carbon-carbon double bond in 9,15,9'-tricis-ζ-Carotene, which is required for biosynthesis of all plant carotenoids. Requires heme b.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W740803

15-cis-Phytofluene (15Z)-Phytofluene	Natural Products Rosaceae Plants Prunus armeniaca L. Source Classification	Drug Intermediate Drug Isomer
15-cis-Phytofluene is a cis-isomer of Phytofluene. 15-cis-Phytofluene is an acyclic carotenoid. 15-cis-Phytofluene acts as a biosynthetic intermediate in carotenoid biosynthesis .

HY-W750692

β-Citraurin	Natural Products Rutaceae Plants Citrus sinensis (L.) Osbeck Source Classification	Drug Derivative
β-Citraurin is a carotenoid. Jasmonates induce β-Citraurin biosynthesis in citrus by activating a CsMPK6-CsMYC2 cascade, thereby affecting fruit coloration .

HY-W750723

Rubixanthin	Other Terpenoids Structural Classification Terpenoids Rosaceae Plants Rosa rubiginosa L. Source Classification	Drug Derivative
Rubixanthin, a carotenoid, is mainly derived from the biosynthesis process of carotenoids in the Flavobacterium strain R-1519 .

Cat. No.	Product Name	Chemical Structure

HY-W778236

Norflurazon-13C,d3
Norflurazon- ¹³C,d₃ (SAN 9789- ¹³C,d₃) is the deuterium and ¹³C-labeled Norflurazon (HY-114849). Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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carotenoid biosynthesis

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products