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Cat. No.: HY-163559

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HPPD-IN-4

HPPD-IN-4 is a Herbicide and HPPD inhibitor with an IC₅₀ of 0.19 μM against Arabidopsis thaliana HPPD. HPPD-IN-4 disrupts carotenoid biosynthesis and exhibits post-emergence herbicidal activity against Abutilon theophrasti and Chenopodium album.

For research use only. We do not sell to patients.

CAS No.: 3028731-23-6
Formula: C₁₉H₁₄F₃NO₄
Molecular Weight:377.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

HPPD-IN-4 Chemical Structure

CAS No.: 3028731-23-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

HPPD-IN-4 (Compound III-29) (25 min) inhibits Arabidopsis thaliana HPPD (AtHPPD) in vitro with an IC₅₀ of 0.19 μM^[1].
HPPD-IN-4 (150 g a.i./ha) produces >90% postemergence inhibition of four weed species (CA and AT) and causes albino symptoms in leaves^[1].
HPPD-IN-4 (300 g a.i./ha) leaves measurable chlorophyll a, chlorophyll b, and carotenoid contents in cotton, peanut, wheat, rice, and corn, including wheat Ca 0.96 mg/g and peanut Ca 1.11 mg/g^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 3028731-23-6
Molecular Weight 377.31
Formula C₁₉H₁₄F₃NO₄
SMILES

O=C1C(C(C2=CN=C(OC3=CC=CC(C(F)(F)F)=C3)C=C2)=O)=C(O)CCC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang CQ, et al. Design, Synthesis, and Biological Activity of Novel Triketone-Containing Phenoxy Nicotinyl Inhibitors of HPPD. Journal of agricultural and food chemistry. 2024 May 22;72(20):11321-11330. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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