Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
conditioned avoidance response
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "conditioned avoidance response" in MCE Product Catalog:
Cat. No.: HY-106605
CAS No.: 61325-80-2
Synonyms: LY 120363
Target:
Research Areas:
Flumezapine (LY 120363) is a potent and balanced antagonist of the dopamine D2 receptor and the 5-hydroxytryptamine receptor (5-HT receptor). Flumezapine does not alter the increase in serum cortisol caused by κ-opioid receptor agonists. Flumezapine inhibits the conditioned avoidance response in rats and has a low risk of extrapyramidal side effects. Flumezapine can be used in antipsychotic research .
Cat. No.: HY-106605S
Synonyms: LY 120363-d8 hydrochloride
Target:
Research Areas:
Thiazesim is a CNS-penetrant GABAA receptor inhibitor, exerting anticonvulsant and antidepressant effects. Thiazesim depresses amygdala output, disrupts conditioned avoidance response in rats. Thiazesim can be used for the research of depression and epilepsy .
Cat. No.: HY-105857A
CAS No.: 3122-01-8
Target:
Research Areas:
Thiazesim hydrochloride is a CNS-penetrant GABAA receptor inhibitor, exerting anticonvulsant and antidepressant effects. Thiazesim hydrochloride depresses amygdala output, disrupts conditioned avoidance response in rats. Thiazesim hydrochloride can be used for the research of depression and epilepsy .
Cat. No.: HY-137935
CAS No.: 42021-34-1
Synonyms: Centbutindole
Target:
Research Areas:
Biriperone is a D1, D2, and 5-HT2A receptor antagonist with pKi values of 6.372, 7.88 and 7.619. Biriperone blocks amphetamine-induced hyperactivity and stereotypy in rodents. Biriperone blocks secondary conditioned avoidance responses in rodents. Biriperone can be used for the research of schizophrenia .
Cat. No.: HY-118477
CAS No.: 173294-84-3
Target:
Research Areas:
Dehydrosertindole is a blood-brain barrier-permeable, orally active inhibitor of the dopamine D2 receptor. Dehydrosertindole occupies striatal dopamine D2 receptors to mediate receptor regulation. Dehydrosertindole is the active metabolite of Sertindole (HY-14543), which distributes rapidly in guinea pig myocardium and inhibits conditioned avoidance responses in rats. Dehydrosertindole can be used in research related to schizophrenia .
Cat. No.: HY-115418
CAS No.: 112892-81-6
Synonyms: U-68553B
Target:
Research Areas:
Alentemol (hydrobromide) is a dopamine antagonist and dihydrophenalene analog with dimethylamino substitution and an orthophenolic hydroxy group relative to the amino nitrogen. Alentemol (hydrobromide) does not impair escape response at a dose that completely suppresses conditioned avoidance in rats .
Cat. No.: HY-123332
CAS No.: 73328-60-6
Target:
Research Areas:
YM-08050 is a new anti-psychotic and Benzamide (HY-Z0283) derivative. YM-08050 inhibits stereotyped behaviors, conditioned avoidance responses, or spontaneous movements induced by Apomorphine (HY-12723) or Methamphetamine .
Cat. No.: HY-106898A
CAS No.: 136777-43-0
Target:
Research Areas:
Carvotroline hydrochloride is an antipsychotic agent and 5-HT2 receptor antagonist, with a Ki value of 211 nM for the 5-HT2 receptor. Carvotroline hydrochloride modulates the activity of the stress-related hypothalamic-pituitary-adrenal axis. Carvotroline hydrochloride exerts a stronger blocking effect on Apomorphine (HY-12723)-induced climbing behavior than on Apomorphine-induced stereotyped behavior. Carvotroline hydrochloride inhibits conditioned avoidance responses in rats and monkeys without inducing catalepsy. Carvotroline hydrochloride can be used in studies related to schizophrenia .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
