257 Results for "

constituents

" in MedChemExpress (MCE) Product Catalog:
Products (257)

257 Results for "constituents" in MCE Product Catalog:

60
Arachidonic acid
Arachidonic acid
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60 Publications Verification
Cat. No.: HY-109590
CAS No.: 506-32-1
Purity:  99.73%
Synonyms: Immunocytophyt
Category:  

Human Gut Microbiota Metabolites Animals Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite

Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid improves cognitive response and cardiovascular function .
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60
Arachidonic acid sodium salt
Arachidonic acid sodium salt
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60 Publications Verification
Cat. No.: HY-109590A
CAS No.: 6610-25-9
Purity:  99.3%
Synonyms: Immunocytophyt sodium salt
Category:  

Animals Ketones, Aldehydes, Acids

Target:  

Endogenous Metabolite

Arachidonic acid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid sodium salt improves cognitive response and cardiovascular function .
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19
Gastrodin
Gastrodin
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19 Cited Publications
Cat. No.: HY-N0115
CAS No.: 62499-27-8
Synonyms: Gastrodine
Category:  

Natural Products Neurological Disease Gastrodia elata Bl. Anti-aging Orchidaceae Phenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis Ferroptosis

Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H2O2-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia .
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16
Ginsenoside Rb1
Ginsenoside Rb1
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16 Cited Publications
Cat. No.: HY-N0039
CAS No.: 41753-43-9
Synonyms: Gypenoside III
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Araliaceae Cancer

Target:  

Na+/K+ ATPase IRAK NF-κB Autophagy Mitophagy HSV

Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na +, K +-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .
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12
Glucosamine
Glucosamine
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12 Cited Publications
Cat. No.: HY-B1125
CAS No.: 3416-24-8
Synonyms: D-Glucosamine; Chitosamine
Category:  

Human Gut Microbiota Metabolites Anti-aging Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides Cancer Monosaccharides

Target:  

CFTR Free Radical Scavengers Endogenous Metabolite Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Autophagy

Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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12
Glucosamine hydrochloride
Glucosamine hydrochloride
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12 Cited Publications
Cat. No.: HY-N0733
CAS No.: 66-84-2
Synonyms: D-(+)-Glucosamine hydrochloride; Chitosamine hydrochloride
Category:  

Microorganisms Animals Endogenous metabolite Disease Research Fields Saccharides Cancer

Target:  

Free Radical Scavengers Endogenous Metabolite Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Autophagy

Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine hydrochloride also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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12
Glucosamine sulfate
Glucosamine sulfate
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12 Cited Publications
Cat. No.: HY-N0487
CAS No.: 29031-19-4
Synonyms: D-Glucosamine sulfate
Category:  

Endogenous metabolite Disease Research Fields Saccharides Cancer

Target:  

Free Radical Scavengers Endogenous Metabolite Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Autophagy

Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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9
Albiflorin
Albiflorin
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9 Cited Publications
Cat. No.: HY-N0037
CAS No.: 39011-90-0
Category:  

Other Monoterpenes Paeonia lactiflora Pall. Terpenoids Plants Paeoniaceae Disease Research Fields Inflammation/Immunology

Target:  

Reactive Oxygen Species (ROS)

Albiflorin, a major constituent contained in peony root, is a brain-penetrant monoterpene glycoside with neuroprotective effects. Albiflorin also has anti-inflammatory, antioxidant and antinociceptive effects .
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9
Stachydrine
Stachydrine
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9 Cited Publications
Cat. No.: HY-N0298
CAS No.: 471-87-4
Category:  

Alkaloids Erythrophleum fordii Oliv. Pyrrole Alkaloids Labiatae Plants Endogenous metabolite Disease Research Fields Cancer

Target:  

NF-κB Endogenous Metabolite

Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway.
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9
Stachydrine hydrochloride
Stachydrine hydrochloride
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9 Cited Publications
Cat. No.: HY-N0738
CAS No.: 4136-37-2
Category:  

Alkaloids Erythrophleum fordii Oliv. Pyrrole Alkaloids Labiatae Plants Disease Research Fields Cancer

Target:  

NF-κB Endogenous Metabolite

Stachydrine hydrochloride is the major active constituent of Leonurus artemisia, which is a potential therapy for cardiovascular diseases . Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities .
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8
(Z)-Guggulsterone
(Z)-Guggulsterone
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8 Cited Publications
Cat. No.: HY-110066
CAS No.: 39025-23-5
Purity:  99.30%
Category:  

Commiphora myrrha (Nees) Engl. Plants Burseraceae Disease Research Fields Cancer Steroids

Target:  

Apoptosis VEGFR Akt Angiotensin-converting Enzyme (ACE) SARS-CoV FXR

(Z)-Guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis . (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection .
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7
Narirutin
Narirutin
0 Images
7 Cited Publications
Cat. No.: HY-N0804
CAS No.: 14259-46-2
Category:  

Flavonoids Flavonones Rutaceae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Citrus

Target:  

Bacterial

Narirutin, one of the active constituents isolated from citrus fruits, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency .
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7
Farrerol
Farrerol
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7 Cited Publications
Cat. No.: HY-N0344
CAS No.: 24211-30-1
Synonyms: (-)-Farrerol
Category:  

Neurological Disease  Rhododendron dauricum Linn. Plants Flavonoids Flavonones Phenols Polyphenols Ericaceae Disease Research Fields Inflammation/Immunology

Target:  

Others

Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .
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5
Arachidonic acid-d8
Arachidonic acid-d8
0 Images
5 Cited Publications
Cat. No.: HY-109590S
CAS No.: 69254-37-1
Purity:  99.00%
Synonyms: Immunocytophyt-d8
Arachidonic acid-d8 is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes .
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5
Mogroside V
Mogroside V
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5 Cited Publications
Cat. No.: HY-N0502
CAS No.: 88901-36-4
Category:  

Triterpenes Terpenoids Cucurbitaceae Metabolic Disease Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Sweeteners Food Research

Target:  

Reactive Oxygen Species (ROS)

Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
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5
Polyphyllin I
Polyphyllin I
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5 Cited Publications
Cat. No.: HY-N0047
CAS No.: 50773-41-6
Category:  

Liliaceae Paris polyphylla Smith Plants Disease Research Fields Saccharides Cancer Steroids

Target:  

JNK mTOR Akt PDK-1 Autophagy Apoptosis

Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis .
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5
Mulberroside A
Mulberroside A
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5 Cited Publications
Cat. No.: HY-N0619
CAS No.: 102841-42-9
Category:  

Stilbenes Morus alba L. Phenols Polyphenols Plants Moraceae Disease Research Fields Inflammation/Immunology

Target:  

TNF Receptor Interleukin Related Tyrosinase

Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.) . Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects . Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM .
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4
(-)-Catechin gallate
(-)-Catechin gallate
0 Images
4 Cited Publications
Cat. No.: HY-N0356
CAS No.: 130405-40-2
Synonyms: (-)-Catechin 3-gallate; (-)-Catechin 3-O-gallate
Category:  

Flavonoids Flavanols Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae

Target:  

COX

(-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes.
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4
Irisflorentin
Irisflorentin
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4 Cited Publications
Cat. No.: HY-N0268
CAS No.: 41743-73-1
Category:  

Iridaceae Flavonoids Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Inflammation/Immunology Isoflavones

Target:  

NO Synthase

Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity .
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4
Curcumenol
Curcumenol
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4 Cited Publications
Cat. No.: HY-N2259
CAS No.: 19431-84-6
Synonyms: (+)-Curcumenol
Category:  

Neurological Disease Terpenoids Sesquiterpenes Plants Curcuma phaeocaulis Valeton Disease Research Fields Inflammation/Immunology Cancer Zingiberaceae

Target:  

Cytochrome P450

Curcumenol ((+)-Curcumenol) is a potent CYP3A4 inhibitor with an IC50 of 12.6 μM, which is one of constituents in the plants of medicinally important genus of Curcuma zedoaria, with neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. Curcumenol ((+)-Curcumenol) suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells .
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