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cytochrome P450 (CYP)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Cytochrome P450 (135) 5-HT Receptor (4) Adenosine Receptor (2) Adrenergic Receptor (2) Aldose Reductase (1) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (10) Antifolate (1) Apoptosis (14) Aryl Hydrocarbon Receptor (1) Autophagy (12) Bacterial (9) Calcium Channel (1) Caspase (2) COX (6) Dopamine Receptor (3) Dopamine β-hydroxylase (2) Drug Intermediate (2) Drug Isomer (1) Drug Metabolite (26) Endogenous Metabolite (8) Environmental Pollutants (4) ERK (2) Ferroptosis (3) FGFR (1) Fluorescent Dye (2) Fungal (14) GABA Receptor (3) Glucocorticoid Receptor (1) Glycosidase (1) HBV (1) HCV (3) HCV Protease (3) Heme Oxygenase (HO) (1) Histamine Receptor (6) HIV (4) HMG-CoA Reductase (HMGCR) (1) Influenza Virus (2) Insecticide (1) Isotope-Labeled Compounds (20) Keap1-Nrf2 (1) mAChR (1) Microtubule/Tubulin (1) Mineralocorticoid Receptor (1) Mitosis (1) MOFs (1) Monoamine Oxidase (2) NAMPT (1) Necroptosis (3) NO Synthase (2) Opioid Receptor (2) p38 MAPK (1) Parasite (5) PKC (2) Platelet-activating Factor Receptor (PAFR) (1) Potassium Channel (4) PPAR (8) PROTACs (1) Pyruvate Kinase (1) Quinone Reductase (1) RAR/RXR (5) Reactive Oxygen Species (ROS) (1) Reference Standards (39) RET (1) Reverse Transcriptase (3) SARS-CoV (6) Serotonin Transporter (2) Sodium Channel (4) STAT (2) Telomerase (2) Thrombopoietin Receptor (7) Thymidylate Synthase (1) Topoisomerase (1) Urotensin Receptor (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (67) Cardiovascular Disease (22) Endocrinology (1) Infection (35) Inflammation/Immunology (47) Metabolic Disease (56) Neurological Disease (44)
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222

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

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GMP Molecules

Fenofibrate Maximum Cited Publications 33 Publications Verification	PPAR Cytochrome P450 Autophagy	Cardiovascular Disease Cancer
Fenofibrate is a selective PPARα agonist with an EC₅₀ of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC₅₀s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for *CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4*, respectively.

Abiraterone 20+ Cited Publications CB-7598	Cytochrome P450	Cancer
Abiraterone is a potent and irreversible *CYP17A1* inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC₅₀s of 2.5 nM and 15 nM, respectively.

Clotrimazole 5+ Cited Publications	Fungal Bacterial Autophagy Antibiotic	Infection Cancer
Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.

Hypericin 5+ Cited Publications	Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase	Infection Neurological Disease Cancer
Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome *P450*). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .

(S)-Mephenytoin (+)-Mephenytoin	Cytochrome P450	Neurological Disease
(S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism .

Cobicistat 10+ Cited Publications GS-9350	Cytochrome P450 HIV	Infection Cancer
Cobicistat is a potent and selective inhibitor of cytochrome P450 3A (CYP3A) enzymes with IC₅₀s of 30-285 nM. Cobicistat is a pharmacokinetic enhancer which increases the overall absorption of several HIV medications.

Phenacetin 1 Publications Verification Acetophenetidin	COX	Inflammation/Immunology
Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats .

4'-Hydroxy diclofenac	Drug Metabolite	Neurological Disease Inflammation/Immunology
4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties .

Tienilic acid 2 Publications Verification Ticrynafen; ANP 3624	Cytochrome P450	Cardiovascular Disease Metabolic Disease
Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent. However, Tienilic acid induces hepatotoxicity. Tienilic acid is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro .

2-Naphthol 1 Publications Verification	Environmental Pollutants Endogenous Metabolite	Others
2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2).

Clomethiazole 4 Publications Verification	GABA Receptor Cytochrome P450	Neurological Disease
Chlormethiazole is an potent and orally active GABA_A agonist . Chlormethiazole inhibits cytochrome P450 isoforms: *CYP2A6* and *CYP2E1* in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus .

1'-Hydroxy bufuralol Ro 03-7410	Drug Metabolite	Metabolic Disease
1'-Hydroxy bufuralol is the main metabolite of Bufuralol (HY-105124) by the cytochrome P450 isoenzymes 2D1 and 2D2 (CYP2D1/2). 1'-Hydroxy bufuralol can be used to determine CYP2D1/2 enzyme activity .

7-Ethoxyresorufin 1 Publications Verification Resorufin ethyl ether	Cytochrome P450 NO Synthase	Others
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of **cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase** .

Abiraterone-d4 CB-7598-d₄	Cytochrome P450	Cancer
Abiraterone-d₄ is the deuterium labeled Abiraterone. Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.

7-Ethoxycoumarin 7-O-Ethylumbelliferone	Cytochrome P450	Metabolic Disease
7-Ethoxycoumarin is a substrate of cytochrome P450 (CYP450). 7-Ethoxycoumarin has been used for the functional characterization of various CYPs and for the generation of 7-hydroxycoumarin (HY-N0573) .

Dafadine-A	Cytochrome P450	Infection Cancer
Dafadine-A is a selective inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans. Dafadine-A inhibits the mammalian ortholog of DAF-9 (CYP27A1). Dafadine-A does not inhibits DAF-12 and sterol- and oxysterol-metabolizing P450s .

Linderane	Cytochrome P450	Inflammation/Immunology
Linderane, isolated from the root of Lindera aggregata, is an irreversible inhibitor **cytochrome P450 2C9 (CYP2C9)**. Linderane has the potential to relieve pain and cramp .

Chlormethiazole hydrochloride 4 Publications Verification Clomethiazole hydrochloride	Cytochrome P450	Neurological Disease
Clomethiazole hydrochloride is a potent and orally active GABA_A agonist . Clomethiazole hydrochloride inhibits cytochrome P450 isoforms: *CYP2A6* and *CYP2E1* in human liver microsomes. Clomethiazole hydrochloride is an anticonvulsant agent and has the potential for treating convulsive status epilepticus .

7-Methoxy-4-(trifluoromethyl)coumarin MFC	Cytochrome P450 Fluorescent Dye	Others
7-Methoxy-4-(trifluoromethyl)coumarin (MFC) is a fluorescent substrate for **cytochrome P450** and can quantify CYP activity .

2-Naphthol-d7	Endogenous Metabolite	Others
2-Naphthol-d₇ is the deuterium labeled 2-Naphthol . 2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2) .

5-Hydroxydiclofenac	Drug Metabolite Apoptosis	Cancer
5-Hydroxydiclofenac is a major metabolite of Diclofenac (HY-15036). 5-Hydroxydiclofenac is formed by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C189, CYP2C19, and CYP2C8. 5-Hydroxydiclofenac shows apoptotic effects in hepatocytes .

(S)-Mephenytoin (Standard) (+)-Mephenytoin (Standard)	Reference Standards Cytochrome P450	Neurological Disease
(S)-Mephenytoin (Standard) is the analytical standard of (S)-Mephenytoin. This product is intended for research and analytical applications. (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism .

Clotrimazole-d5	Isotope-Labeled Compounds Fungal Bacterial Autophagy Antibiotic	Infection Cancer
Clotrimazole-d₅ is the deuterium labeled Clotrimazole. Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity .

Nicotelline Nicotellin	Cytochrome P450	Neurological Disease
Nicotelline (Nicotellin) is a nicotine-related alkaloid, as well as a weak inhibitor of human cDNA-expressed **cytochrome P-450** 2A6 (CYP2A6). CYP2A6 mediates coumarin 7-hydroxylation, while Nicotelline fails to exhibit inhibition at 300 μM. Nicotelline can be used as a tracer and biomarker of particulate matter (PM) derived from tobacco smoke .

TP0472993	Cytochrome P450	Metabolic Disease
CYP4A11/CYP4F2-IN-2 is a potent and orally active dual inhibitor of cytochrome P450 (CYP) 4A11 and *CYP4F2, with IC₅₀s of 140 nM and 40 nM, respectively. CYP4A11/CYP4F2-IN-2* has potential for the research of renal diseases .

Phenacetin-d5 Acetophenetidin-d₅	COX	Inflammation/Immunology
Phenacetin-d₅ is the deuterium labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats .

CYP3A4-IN-1	Cytochrome P450	Infection
CYP3A4-IN-1 (compound 5a) is a potent **cytochrome P450 3A4 (CYP3A4) inhibitor with an IC₅₀** value of 0.085 µM .

2,7-Dimethylnaphthalene	Cytochrome P450	Metabolic Disease
2,7-Dimethylnaphthalene is a selective cytochrome P450 1A2 (CYP1A2) enzyme inhibitor with an IC₅₀ of 65 μM. 2,7-Dimethylnaphthalene can be used for the research of metabolic disease .

Methoxsalen-d3 8-Methoxypsoralen-d₃; Xanthotoxin-d₃; 8-MOP-d₃	Cytochrome P450	Inflammation/Immunology
Methoxsalen-d₃ is the deuterium labeled Methoxsalen[1]. Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight[2].

Bilberry Extract	Cytochrome P450	Metabolic Disease
Bilberry Extract is a bilberry extract, and its components include: Anthocyanidins. Bilberry Extract has potential antioxidant activity and can regulate specific metabolic enzymes in the liver, such as cytochrome P450 (CYP) 2C11 and CYP2E1 involved in drug metabolism. .

Dipropyl disulfide Propyl Disulfide; DPDS	Environmental Pollutants Cytochrome P450	Others
Dipropyl disulfide is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. Both flavincontaining monooxygenases (FMO) and cytochrome P450 enzymes (CYPs) are involved in dipropyl disulfide oxidation. Dipropyl disulfide forms two metabolites: propylglutathione sulfide conjugate and propylthiol .

CYP1B1 ligand 3	Cytochrome P450	Cancer
CYP1B1 ligand 3 (Compound A1) is a selective inhibitor for cytochrome P450 enzyme *CYP1B1* with an IC₅₀ of 11.9 nM. CYP1B1 ligand 3 can be utilized for the synthesis of PROTAC CYP1B1 degrader-2 (HY-158429) .

7-Ethoxyresorufin-d5 Resorufin ethyl ether-d₅	Isotope-Labeled Compounds Cytochrome P450 NO Synthase	Others
7-Ethoxyresorufin-d₅ is deuterium labeled 7-Ethoxyresorufin. 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase .

3-Methylbenzofuran	Cytochrome P450	Cancer
3-Methylbenzofuran is a cytochrome P450 *CYP2A6* inhibitor. With an IC₅₀ of 7.35 μM. 3-Methylbenzofuran can be used for the research of tobacco-related cancer .

5-Hydroxy-8-methoxypsoralen 1 Publications Verification 5-Hydroxyxanthotoxin	Drug Metabolite	Inflammation/Immunology
5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite of Xanthotoxin. Xanthotoxin is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight .

3-Methylquinoline	Cytochrome P450	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
3-Methylquinoline is a selective **cytochrome P450** (CYP1A2) inhibitor with an IC₅₀ of 13 μM. 3-Methylquinoline can reduce the metabolic clearance of CYP1A2 substrate drugs. 3-Methylquinoline can inhibit the activation of carcinogenic precursors .

Glucoarabin	Cytochrome P450 Quinone Reductase	Cancer
Glucoarabin is a bioactive glucosinolate. In Hepa1c1c7 cells, hydrolyzed Glucoarabin (hGSL 9) upregulates the phase II detoxification enzyme quinone reductase (NQO1), with no effect on cytochrome P450 (CYP) 1A1 activity .

CYP4A11/CYP4F2-IN-1	Cytochrome P450	Metabolic Disease
CYP4A11/CYP4F2-IN-1 is a potent dual inhibitor of cytochrome P450 (CYP) 4A11 and *CYP4F2, with IC₅₀s of 19 nM and 17 nM, respectively. CYP4A11/CYP4F2-IN-1* has potential for the research of renal diseases .

(S)-6-O-Desmethylnaproxen (S)-6-Desmethyl Naproxen	COX	Inflammation/Immunology
(S)-6-O-Desmethylnaproxen ((S)-6-Desmethyl Naproxen) is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen). (S)-6-O-Desmethylnaproxen is formed from (S)-naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.

EDDP perchlorate	Drug Metabolite	Others
EDDP perchlorate is an N-desmethyl metabolite of Methadone by intestinal, hepatic, and cytochrome P450 (CYP) 3A4 .

RPR132595A NPC	Drug Metabolite	Cancer
RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by **cytochrome P-450 3A4 (CYP3A4)** and finally excreted through urine .

Promethazine sulfoxide	Histamine Receptor	Neurological Disease
Promethazine sulfoxide is a metabolite of the histamine H1 receptor antagonist Promethazine (HY-B1296). It is formed from promethazine by the cytochrome P450 (CYP) isoform CYP2D6.

CYP1B1-IN-5	Cytochrome P450	Cancer
CYP1B1-IN-5 (Compound 6q) is a potent and selective cytochrome P450 1B1 (CYP1B1) inhibitor with an IC₅₀ of 4.7 nM .

Resorufin methyl ether Methoxyresorufin	Cytochrome P450	Others
Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate . Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents .

Clotrimazole (Standard)	Reference Standards Fungal Bacterial Autophagy Antibiotic	Infection Cancer
Clotrimazole (Standard) is the analytical standard of Clotrimazole. This product is intended for research and analytical applications. Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.

Echihumiline	Cytochrome P450	Metabolic Disease
Echihumiline is an alkaloid targeting hepatic cytochrome P450 enzymes (CYP450). Echihumiline induces DNA cross-linking and oxidative stress in hepatocytes, leading to liver necrosis and fibrosis. Echihumiline is promising for research of liver diseases .

Cat. No.	상품명

HY-L922

Good ADMET Diversity Library

25000 compounds

A diverse compound library with favorable ADMET properties (Absorption, Distribution, Metabolism, Excretion, and Toxicity) is crucial in drug discovery. Early evaluation of ADMET properties allows for the exclusion of molecules with unfavorable profiles at the initial stages, thereby reducing the risk of late-stage development failures, lowering R&D costs, and accelerating optimization of lead compounds. Based on predictions from ADMET-related AI algorithms, the compounds in this library are predicted to exhibit favorable oral bioavailability (F > 30%), reasonable plasma protein binding (PPB < 98%), minimized CYP3A4 inhibition potential (inhibition probability < 50%, CYP3A4 is the most critical drug-metabolizing enzyme in the cytochrome P450 family) , low toxicity profiles, with 140 potentially toxic substructures pre-identified and excluded via substructure searching to eliminate compounds containing hazardous fragments. The diversity library enables broad applicability in high-throughput screening (HTS) and high-content screening (HCS).

Cat. No.	상품명	Type

HY-D0145

7-Ethoxyresorufin 1 Publications Verification Resorufin ethyl ether	Fluorescent Dyes
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of **cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase** .

HY-116862

Dibenzylfluorescein

DBF

Fluorescent Dyes

Dibenzylfluorescein (DBF) is a fluorogenic probe (Fluoresecent dye) that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is typically used near its K_m value of 0.87-1.9 μM (Ex=485 nm，Em=535 nm). Dibenzylfluorescein is used to detect changes in CYP catalytic activity caused by drugs or disease .

HY-W027773

7-Methoxy-4-(trifluoromethyl)coumarin MFC	Fluorescent Dyes
7-Methoxy-4-(trifluoromethyl)coumarin (MFC) is a fluorescent substrate for **cytochrome P450** and can quantify CYP activity .

HY-D0144

Resorufin methyl ether Methoxyresorufin	Fluorescent Dyes
Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate . Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents .

HY-17356G

Fenofibrate

Fluorescent Dyes

Fenofibrate (GMP) is Fenofibrate (HY-17356) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Fenofibrate is a selective PPARα agonist with an EC₅₀ of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC₅₀s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively.

Cat. No.	상품명	Type

HY-17356G

Fenofibrate

Biochemical Assay Reagents

HY-N9934R

(-)-3-Dehydroshikimic acid (Standard) 3-DHS (Standard); 5-Dehydroshikimic acid (Standard)	Biochemical Assay Reagents
Isonicotinic acid (Standard) is the analytical standard of Isonicotinic acid. This product is intended for research and analytical applications. Isonicotinic acid is a metabolite of Isoniazid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the Isoniazid to Isonicotinic acid biotransformation also to be catalyzed by cytochrome P450 (CYP) enzymes, e.g., CYP2C .

Cat. No.	상품명

HY-K6304

Human iPSC/ESC Hepatocyte Induction Differentiation Kit

MCE Human iPSC/ESC Hepatocyte Induction Differentiation Kit enables the efficient generation of hepatocyte-like cells with a high degree of maturation within 21 d. The resulting cells stably express multiple key hepatic functional markers, including albumin (ALB), cytochrome P450 (CYP) family enzymes, and other liver-specific functional molecules, and exhibit typical hepatocellular phenotypes and functions.

Species:	Human (6)
Tag:	SUMO (2) His (8) GST (1)
Source:	Sf9 insect cells (1) P. pastoris (1) E. coli (7)

Cat. No.	Compare	상품명	Species	Source	Image

HY-P72164

	CYP21A2 Protein, Human (His) CYP21; 21 OHase; 21-OHase; CA21H ; CAH1; CP21A_HUMAN; CPS1; CYP21A 2; CYP21A2; CYP21B; cytochrome P-450c21; cytochrome P450 21; cytochrome P450 C21B; cytochrome P450 XXI; cytochrome P450; family 21; subfamily A; polypeptide 2; cytochrome P450; subfamily XXIA steroid 21 hydroxylase;	Human	E. coli
	CYP21A2 Protein, a cytochrome P450 monooxygenase, crucially hydroxylates progesterone and 17alpha-hydroxyprogesterone at C-21, yielding vital intermediates for mineralocorticoid and glucocorticoid biosynthesis in adrenal steroidogenesis. This enzymatic process involves molecular oxygen, with NADPH providing essential electrons via cytochrome P450 reductase (CPR). CYP21A2 plays a pivotal role in regulating adrenal cortex hormone production. CYP21A2 Protein, Human (His) is the recombinant human-derived CYP21A2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700629

	CYP102A1 Protein, Priestia megaterium (P. pastoris, His) Bifunctional cytochrome P450; NADPH--P450 reductase; cytochrome P450BM-3; Fatty acid monooxygenase; Flavocytochrome P450 BM3	Others	P. pastoris
	The CYP102A1 protein acts as a fatty acid monooxygenase, catalyzing the hydroxylation of fatty acids at various positions. The protein also exhibits NADPH-dependent reductase activity, promoting electron transfer within its domain. CYP102A1 Protein, Priestia megaterium (P. pastoris, His) is the recombinant CYP102A1 protein, expressed by P. pastoris , with C-6*His labeled tag.

HY-P72163

	CYP11B2 Protein, Human (His-SUMO) ALDOS; Aldosterone synthase; Aldosterone-synthesizing enzyme; C11B2_HUMAN; CYP11B2; CYPXIB2; cytochrome P-450Aldo; cytochrome P-450C18; cytochrome P450 11B2; cytochrome P450 11B2; mitochondrial; mitochondrial; P-450Aldo; P-450C18; Steroid 18-hydroxylase	Human	E. coli
	CYP11B2 Protein, a cytochrome P450 monooxygenase, synthesizes aldosterone, pivotal for salt and water balance, impacting blood pressure and cardiovascular health. Mechanistically, it orchestrates three oxidative reactions, forming aldosterone, utilizing molecular oxygen and a mitochondrial transfer system. Additionally, CYP11B2 may be involved in the androgen metabolic pathway, expanding its physiological roles. CYP11B2 Protein, Human (His-SUMO) is the recombinant human-derived CYP11B2 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P705910

	CYP3A5 Protein, Human (His) cytochrome P450 3A5; EC:1.14.14.1; CYPIIIA5; cytochrome P450-PCN3; CYP3A5	Human	E. coli

HY-P74210

	CYP3A4 Protein, Human (His) 1 Publications Verification cytochrome P450 3A4; CYPIIIA3; CYP3A4; CYP3A3	Human	E. coli
	The CYP3A4 protein, encoded by the CYP3A4 gene, is a key enzyme in drug metabolism and the synthesis of cholesterol, steroids, and lipids. It localizes to the endoplasmic reticulum and is induced by glucocorticoids and certain drugs. CYP3A4 Protein, Human (His) is the recombinant human-derived CYP3A4 protein, expressed by E. coli , with N-10*His labeled tag.

HY-P705925

	CYP11A1 Protein, Human (His, SUMO) Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase (side chain cleaving); Cholesterol side chain cleavage enzyme; Cholesterol side chain cleavage enzyme mitochondrial; Cholesterol side-chain cleavage enzyme; CP11A_HUMAN; CYP11A; CYP11A1; CYPXIA1; cytochrome P450 11A1; cytochrome P450 11A1 mitochondrial; cytochrome P450 family 11 subfamily A polypeptide 1; cytochrome P450 subfamily XIA; cytochrome P450(scc); cytochrome P450C11A1; mitochondrial; P450SCC; Steroid 20 22 lyase	Human	E. coli

HY-P72049

	CYP51 Protein, Mycobacterium tuberculosis (sf9, His) cyp51; MT0788Lanosterol 14-alpha demethylase; EC 1.14.14.154; CYPLI; cytochrome P450 51; cytochrome P450-14DM; cytochrome P450-LIA1; Sterol 14-alpha demethylase	Others	Sf9 insect cells
	CYP51 Proteinas is a sterol 14α-demethylase that acts with an unknown physiological substrate and accepts electrons from the iron-sulfur ferredoxin Fdx. In vitro, it catalyzes the C14-demethylation of lanosterol, 24,25-dihydrolanosterol, and obtanyol, showing stereoselectivity in producing 8,14-diene. CYP51 Protein, Mycobacterium tuberculosis (sf9, His) is the recombinant CYP51 protein, expressed by Sf9 insect cells , with N-10*His labeled tag.

HY-P72165

	ERG11 Protein, Saccharomyces cerevisiae (GST) ERG11; CYP51; YHR007CLanosterol 14-alpha demethylase; EC 1.14.14.154; CYPLI; cytochrome P450 51; cytochrome P450-14DM; cytochrome P450-LIA1; Sterol 14-alpha demethylase	Others	E. coli
	ERG11 Proteinas is a sterol 14α-demethylase, a key enzyme in the ergosterol biosynthetic pathway, particularly in the late pathway that occurs in the endoplasmic reticulum membrane. ERG11 catalyzes the three-step removal of the 14α-methyl group from lanosterol, releasing it as a formate, resulting in the conversion of the sterol into a key intermediate in ergosterol biosynthesis. ERG11 Protein, Saccharomyces cerevisiae (GST) is the recombinant ERG11 protein, expressed by E. coli , with N-GST labeled tag.

HY-P702798

	CYP7A1 Protein, Human (His) cytochrome P450 7A1; 24-hydroxycholesterol 7-alpha-hydroxylase; CYPVII; Cholesterol 7-alpha-hydroxylase	Human	E. coli
	CYP7A1 Protein, Human (His) is the recombinant human-derived CYP7A1, expressed by E. coli , with N-6*His labeled tag.

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Host:	Mouse (14) Rabbit (17)
Reactivity:	Human (29) Rat (15) Mouse (16) Monkey (2) Dog (2) human (1) Golden hamster (1)
Application:	IHC-P (16) ICC/IF (14) IF-Tissue (2) IP (5) IHC-F (1) WB (25) FC (13) ELISA (3)
Isotype:	IgG (17) IgG1 (6) IgG2a (2) IgG2b (4)
Conjugation:	Non-conjugated (30)
Clonality:	Polyclonal (2) Monoclonal (20) Recombinant (13)
Modification:	Unmodified (23)

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HY-P82091

	Cytochrome P450 1B1 Antibody (YA1836) CYP1B1; cytochrome P450 1B1; CYPIB1	WB, IHC-P, FC	Human, Mouse, Rat
	Cytochrome P450 1B1 Antibody (YA1836) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 1B1.

HY-P82557

	Cytochrome P450 2E1 Antibody (YA2302) CYP2E1; CYP2E; cytochrome P450 2E1; 4-nitrophenol 2-hydroxylase; CYPIIE1; cytochrome P450-J	WB	Human, Mouse, Rat
	Cytochrome P450 2E1 Antibody (YA2302) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 2E1.

HY-P83639

	Cytochrome P450 2D6 Antibody (YA3384) CYP2D6; CYP2DL1; cytochrome P450 2D6; CYPIID6; cytochrome P450-DB1; Debrisoquine 4-hydroxylase	WB, IHC-P, ICC/IF, FC	Human
	Cytochrome P450 2D6 Antibody (YA3384) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 2D6.

HY-P87408A

	CYP1A1 Antibody (YA7096)(PBS only) cytochrome P450 1A1, CYPIA1, cytochrome P450 form 6, cytochrome P450-C, cytochrome P450-P1, Hydroperoxy icosatetraenoate dehydratase, CYP1A1	IHC-P, ELISA	Human
	CYP1A1 Antibody (YA7096) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CYP1A1.

HY-P82421

	Cytochrome P450 2C9 Antibody (YA2166) CPC9; CYP2C; CYP2C10; CYP2C9; CYPIIC9; P450 PB1; P450MP	WB, ICC/IF, FC	Human
	Cytochrome P450 2C9 Antibody (YA2166) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 2C9.

HY-P81245

	Cytochrome P450 1A2 Antibody (YA3505) cytochrome P450 1A2; cytochrome P450, family 1, subfamily a, polypeptide 2; cytochrome P450 family 1 polypeptide 2; cytochrome P450 subfamily I aromatic compound inducible polypeptide 2; Cyp1a2; CYPD45; P-450d; RATCYPD45; CP12; CP 12; P3-450; Aryl hydrocarbon hydroxylase; Dioxin inducable P3 45; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P450 4; P450 form 4; P450 P3; P450(PA); Xenobiotic monooxygenase; P450 1A2.	WB, ICC/IF, FC	Human
	Cytochrome P450 1A2 Antibody (YA3505) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 1A2.

HY-P85566

	Cytochrome P450 17A1 Antibody (YA5258) 20 lyase; CP17A_HUMAN; CPT7; CYP17; CYP17A1; CYPXVII; cytochrome P450 17A1; cytochrome P450 family 17; cytochrome P450 family 17 subfamily A polypeptide 1; cytochrome P450 subfamily XVII; steroid 17 alpha hydroxylase; adrenal hyperplasia; cytochrome P450 XVIIA1; cytochrome P450-C17; cytochrome P450c17; OTTHUMP00000020382; P450 C17; P450c17; S17AH; Steroid 17 alpha hydroxylase/17,20 lyase; Steroid 17 alpha monooxygenase; Steroid 17-alpha-hydroxylase/17; Steroid 17-alpha-monooxygenase.	WB	Human
	Cytochrome P450 17A1 Antibody (YA5258) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cytochrome P450 17A1.

HY-P82376

	Cytochrome P450 24A1 Antibody (YA2121) CYP24A1; CYP24; 1; 25-dihydroxyvitamin D(3) 24-hydroxylase; mitochondrial; 24-OHase; Vitamin D(3) 24-hydroxylase; cytochrome P450 24A1; cytochrome P450-CC24	WB	Human
	Cytochrome P450 24A1 Antibody (YA2121) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 24A1.

HY-P89669

	CYP3A5 Antibody (YA9013) cytochrome P450 3A5, CYPIIIA5, cytochrome P450-PCN3, CYP3A5	WB, ICC/IF, IF-Tissue, IHC-P, IP	human
	CYP3A5 Antibody (YA9013) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CYP3A5.

HY-P88272

	CYP2B6 (Cytochrome P450 2B6) Antibody (YA7956) CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450	IHC-P, ICC/IF, FC	Human, Dog, Rat, Monkey, Mouse
	CYP2B6 (Cytochrome P450 2B6) Antibody (YA7956) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CYP2B6 (Cytochrome P450 2B6).

HY-P88250

	CYP2J2 (Cytochrome p450 2J2) Antibody (YA7934) CPJ2	WB, ICC/IF, FC	Human
	CYP2J2 (Cytochrome p450 2J2) Antibody (YA7934) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CYP2J2 (Cytochrome p450 2J2).

HY-P82342

	Cytochrome P450 4A/CYP4A11 Antibody (YA2087) cytochrome P450 family 4 subfamily A member 11; CP4Y; CYP4A2; CYP4AII; CYPIVA11	WB, IHC-P, IP	Human, Mouse, Rat
	Cytochrome P450 4A/CYP4A11 Antibody (YA2087) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 4A/CYP4A11.

HY-P88272A

	CYP2B6 (Cytochrome P450 2B6) Antibody (YA7956)(PBS only) CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450	IHC-P, ICC/IF, FC	Human, Dog, Rat, Monkey, Mouse
	CYP2B6 (Cytochrome P450 2B6) Antibody (YA7956) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CYP2B6 (Cytochrome P450 2B6).

HY-P80547

	Aromatase Antibody (YA611) 1 Publications Verification CYP19A1; ARO1; CYAR; CYP19; cytochrome P450 19A1; Aromatase; CYPXIX; cytochrome P-450AROM; Estrogen synthase	WB, IP	Human, Mouse, Rat
	Aromatase Antibody (YA611) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aromatase.

HY-P88250A

	CYP2J2 (Cytochrome p450 2J2) Antibody (YA7934)(PBS only) CPJ2	WB, ICC/IF, FC	Human
	CYP2J2 (Cytochrome p450 2J2) Antibody (YA7934) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CYP2J2 (Cytochrome p450 2J2).

HY-P80640

	Cytochrome P450 17A1 Antibody (YA786) CPT7; CYP17; P450C17; S17AH; CYP17A1	WB	Human
	Cytochrome P450 17A1 Antibody (YA786) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Cytochrome P450 17A1.

HY-P82514

	Cytochrome P450 26A1 Antibody (YA2259) CP26; CYP26; cyp26a1; hP450RAI; P450RAI; P450RAI1	WB, IHC-P	Human, Rat
	Cytochrome P450 26A1 Antibody (YA2259) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 26A1.

HY-P81244

	CYP2E1 Antibody (YA9212) CYP2E1; CYP2E; cytochrome P450 2E1; 4-nitrophenol 2-hydroxylase; CYPIIE1; cytochrome P450-J	WB, IHC-P, IF-Tissue	Human, Mouse, Rat
	CYP2E1 Antibody (YA9212) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CYP2E1.

HY-P82418

	Cytochrome P450 27A1 Antibody (YA2163) CYP27A1; CYP27; Sterol 26-hydroxylase; mitochondrial; 5-beta-cholestane-3-alpha; 7-alpha; 12-alpha-triol 27-hydroxylase; cytochrome P-450C27/25; cytochrome P450 27; Sterol 27-hydroxylase; Vitamin D(3) 25-hydroxylase	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Cytochrome P450 27A1 Antibody (YA2163) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 27A1.

HY-P80547A

	Aromatase Antibody (YA611)(PBS only) CYP19A1; ARO1; CYAR; CYP19; cytochrome P450 19A1; Aromatase; CYPXIX; cytochrome P-450AROM; Estrogen synthase	WB, IP	Human, Mouse, Rat
	Aromatase Antibody (YA611) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aromatase.

HY-P80640A

	Cytochrome P450 17A1 Antibody (YA786)(PBS only) CPT7; CYP17; P450C17; S17AH; CYP17A1	WB	Human
	Cytochrome P450 17A1 Antibody (YA786) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Cytochrome P450 17A1.

HY-P88197

	CYP2A6 (Cytochrome P450 2A6) Antibody (YA7881) CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	CYP2A6 (Cytochrome P450 2A6) Antibody (YA7881) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CYP2A6 (Cytochrome P450 2A6).

HY-P88197A

	CYP2A6 (Cytochrome P450 2A6) Antibody (YA7881)(PBS only) CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	CYP2A6 (Cytochrome P450 2A6) Antibody (YA7881) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CYP2A6 (Cytochrome P450 2A6).

HY-P81069

	CYP7A1 Antibody CYP7A1; CYP7; Cholesterol 7-alpha-monooxygenase; CYPVII; Cholesterol 7-alpha-hydroxylase; cytochrome P450 7A1	WB	Human, Mouse
	CYP7A1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CYP7A1.

HY-P81223

	CYP11A1 Antibody 2 Publications Verification Cholesterol 20 22 desmolase antibody Cholesterol desmolase antibody; Cholesterol monooxygenase (side chain cleaving) antibody; Cholesterol side chain cleavage enzyme antibody; Cholesterol side chain cleavage enzyme mitochondrial antibody; Cholesterol side-chain cleavage enzyme antibody; CP11A_HUMAN antibody; CYP11A antibody; CYP11A1 antibody; CYPXIA1 antibody; cytochrome P450 11A1 antibody; cytochrome P450 11A1 mitochondrial antibody; cytochrome P450 family 11 subfamily A polypeptide 1 antibody; cytochrome P450 subfamily XIA antibody; cytochrome P450(scc) antibody; cytochrome P450C11A1 antibody; mitochondrial antibody; P450SCC antibody; Steroid 20 22 lyase antibody;	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat
	CYP11A1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CYP11A1.

HY-P85425

	CYP7A1 Antibody (YA5117) CYP7A1; CYP7; Cholesterol 7-alpha-monooxygenase; CYPVII; Cholesterol 7-alpha-hydroxylase; cytochrome P450 7A1	WB	Human, Golden hamster
	CYP7A1 Antibody (YA5117) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CYP7A1.

HY-P84018

	Cytochrome P450 3A4 Antibody (YA3715) HLP; CP33; CP34; CYP3A; NF-25; CYP3A3; P450C3; CYPIIIA3; CYPIIIA4; P450PCN1	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat
	Cytochrome P450 3A4 Antibody (YA3715) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cytochrome P450 3A4.

HY-P82925

	Thromboxane A Synthase Antibody (YA2670) TBXAS1; CYP5; CYP5A1; Thromboxane-A synthase; TXA synthase; TXS; cytochrome P450 5A1	WB	Human, Mouse
	Thromboxane A Synthase Antibody (YA2670) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Thromboxane A Synthase.

HY-P83620

	Cytochrome P450 3A4 Antibody (YA3365) HLP; CP33; CP34; CYP3A; NF-25; CYP3A3; P450C3; CYPIIIA3; CYPIIIA4; P450PCN1; CYP3A4	WB, IHC-P, IP	Human
	Cytochrome P450 3A4 Antibody (YA3365) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 3A4.

HY-P84018A

	Cytochrome P450 3A4 Antibody (YA3715)(PBS only) HLP; CP33; CP34; CYP3A; NF-25; CYP3A3; P450C3; CYPIIIA3; CYPIIIA4; P450PCN1	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat
	Cytochrome P450 3A4 Antibody (YA3715) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cytochrome P450 3A4.

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HY-114759

MS-PPOH 1 Publications Verification		Alkynes
MS-PPOH is a potent and selective **cytochrome P450** (CYP) epoxygenase inhibitor . MS-PPOH inhibits *CYP2C8* and *CYP2C9* with IC₅₀s of 15 and 11 μM, respectively . MS-PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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cytochrome P450 (CYP)

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