diseases of digestive system

By Targets:	ACSL Family (1) Akt (2) Bacterial (2) CD44 (2) Cytochrome P450 (1) Dopamine Receptor (2) Drug Derivative (1) Endogenous Metabolite (2) Histamine Receptor (1) Interleukin Related (2) PI3K (2)
By Research Areas:	Cancer (3) Endocrinology (1) Inflammation/Immunology (7) Metabolic Disease (5) Neurological Disease (4)

Targets Recommended: Complement System

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0633D

Hyaluronic acid sodium (MW 200-1560)	CD44 Endogenous Metabolite Bacterial Akt PI3K	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Hyaluronic acid sodium (MW 200-1560) is a biopolymer composed of repeating disaccharide units, with a molecular weight of 200-1560. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid sodium exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid sodium activates PI3K-Akt signaling. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid sodium is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid sodium can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid sodium can lubricate the corneal endothelium. Hyaluronic acid sodium can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid sodium has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid sodium can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .

HY-B0633E

Hyaluronic acid, low endotoxin Hyaluronan, low endotoxin; Hyaluronate, low endotoxin	Endogenous Metabolite CD44 Bacterial Akt PI3K	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Hyaluronic acid, low endotoxin (Hyaluronan, low endotoxin) is a biopolymer composed of repeating disaccharide units containing low levels of endotoxin. Hyaluronic acid is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid activates PI3K-Akt signaling. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid can lubricate the corneal endothelium. Hyaluronic acid can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .

HY-B1164

Bromopride 2 Publications Verification	Dopamine Receptor	Neurological Disease
Bromopride is a selective, irreversible, competitive, and orally effective dopamine D2 receptor antagonist. Bromopride can pass through the blood-brain barrier, inhibit the vomiting center, and enhance gastrointestinal motility, exerting antiemetic and gastrointestinal motility effects. Bromopride antagonizes dopamine-mediated vomiting reflexes and promotes gastrointestinal smooth muscle contraction, and has no adverse effects on abdominal wall healing in rats with postoperative abdominal infection. Bromopride can be used for the study of digestive system diseases (such as gastric hypomotility, nausea and vomiting) .

HY-177850

ACSL5-IN-3	ACSL Family	Metabolic Disease Endocrinology Cancer
ACSL5-IN-3 (page 115 line 11) is an ACSL5 inhibitor. ACSL5-IN-3 can be used for research of tumours, digestive system diseases, and endocrine and metabolic diseases .

HY-P991277

QX-004N HS-20137	Interleukin Related	Inflammation/Immunology
QX-004N (HS-20137) is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). QX-004N is promising for research of immune system diseases and diseases of digestive system .

HY-Z2667

(R)-Esomeprazole (R)-Omeprazole; (+)-Omeprazole	Cytochrome P450	Metabolic Disease Inflammation/Immunology
(R)-Esomeprazole ((R)-Omeprazole; (+)-Omeprazole) is an orally active cytochrome P450 2C19, CYP3A4, and CYP2C9-related metabolic modulator. (R)-Esomeprazole can be used in studies of digestive system diseases and compound metabolic interactions .

HY-B1164A

Bromopride hydrochloride	Dopamine Receptor	Neurological Disease
Bromopride hydrochloride is a selective, irreversible, competitive, and orally active dopamine D2 receptor antagonist. Bromopride hydrochloride can pass through the blood-brain barrier, inhibit the vomiting center, and enhance gastrointestinal motility, exerting antiemetic and gastrointestinal motility effects. Bromopride hydrochloride antagonizes dopamine-mediated vomiting reflexes and promotes gastrointestinal smooth muscle contraction, and has no adverse effects on abdominal wall healing in rats with postoperative abdominal infection. Bromopride hydrochloride can be used for the study of digestive system diseases (such as gastric hypomotility, nausea and vomiting) .

HY-P991276

FM-303	Interleukin Related	Inflammation/Immunology
FM-303 is a monoclonal antibody inhibitor targeting interleukin-23 (IL-23). FM-303 is promising for research of immune system diseases and diseases of digestive system .

HY-105671

Balazipone	Drug Derivative	Inflammation/Immunology
Balazipone is a phenylmethylene-2,4-pentanedione compound with anti-inflammation activity. Balazipone can be used for digestive system diseases research, such as Crohn's disease .

HY-19179

TRM-115	Histamine Receptor	Metabolic Disease
TRM-115 is a histamine H2 receptor antagonist. TRM-115 is promising for research of digestive system disease .

HY-N16736

Alpinenone	Others	Inflammation/Immunology
Alpinenone is a sesquiterpene compound isolated from nootropic fruits. Alpinenone exerts anti-inflammatory activity by inhibiting overproduction of nitric oxide (NO) and has traditionally had antidiarrheal, diuretic properties. Alpinenone can be used to study inflammation-related diseases and digestive and urinary system diseases .

HY-N15354

Jujubasaponin IV	Others	Others
Jujubasaponin IV is a triterpenoid saponin compound found in Zizyphi Fructus. Animal studies have shown that Jujubasaponin IV possesses certain anti-ulcer activity, possibly through mechanisms such as enhancing the gastric mucosal barrier or inhibiting gastric acid secretion. Jujubasaponin IV can be used in research on digestive system diseases, particularly in the study of gastric ulcer mechanisms .

Cat. No.	Product Name

HY-L238

Mongolian Medicine Compound Library	2,383 compounds
Mongolian medicine refers to drugs used for disease prevention and treatment under the guidance of Mongolian medical theory. Originating from the vast grasslands and desert regions of northern China, Mongolian medicine developed under specific natural conditions and a nomadic lifestyle, forming a unique theoretical system and treatment methods. It emphasizes the balance between the human body and the natural environment and has demonstrated distinct efficacy in treating digestive system diseases, rheumatism, skin diseases, and various chronic conditions. For example, Mongolian medicine often uses Chinese red date for palpitations and angina pectoris, sea buckthorn to relieve coughs, reduce phlegm, promote blood circulation, and remove blood stasis, and scabious to clear lung heat and treat liver heat diseases. The application of these characteristic Mongolian medicines embodies the profound wisdom of Mongolian medical practice. With the advancement of modern technology, research on Mongolian medicine continues to deepen. Systematic studies on the chemical composition and pharmacological effects of Mongolian medicines can provide new ideas and methods for modern drug development. MCE has collected 2,383 characteristic natural products derived from Mongolian medicines, with 400+ plant sources of Mongolian medicine.

Mongolian Medicine Compound Library

2,383 compounds

Mongolian medicine refers to drugs used for disease prevention and treatment under the guidance of Mongolian medical theory. Originating from the vast grasslands and desert regions of northern China, Mongolian medicine developed under specific natural conditions and a nomadic lifestyle, forming a unique theoretical system and treatment methods. It emphasizes the balance between the human body and the natural environment and has demonstrated distinct efficacy in treating digestive system diseases, rheumatism, skin diseases, and various chronic conditions. For example, Mongolian medicine often uses Chinese red date for palpitations and angina pectoris, sea buckthorn to relieve coughs, reduce phlegm, promote blood circulation, and remove blood stasis, and scabious to clear lung heat and treat liver heat diseases. The application of these characteristic Mongolian medicines embodies the profound wisdom of Mongolian medical practice.

With the advancement of modern technology, research on Mongolian medicine continues to deepen. Systematic studies on the chemical composition and pharmacological effects of Mongolian medicines can provide new ideas and methods for modern drug development.

MCE has collected 2,383 characteristic natural products derived from Mongolian medicines, with 400+ plant sources of Mongolian medicine.

Cat. No.	Product Name	Type

HY-B0633E

Hyaluronic acid, low endotoxin Hyaluronan, low endotoxin; Hyaluronate, low endotoxin	Biochemical Assay Reagents
Hyaluronic acid, low endotoxin (Hyaluronan, low endotoxin) is a biopolymer composed of repeating disaccharide units containing low levels of endotoxin. Hyaluronic acid is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid activates PI3K-Akt signaling. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid can lubricate the corneal endothelium. Hyaluronic acid can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .

Hyaluronic acid, low endotoxin

Hyaluronan, low endotoxin; Hyaluronate, low endotoxin

Biochemical Assay Reagents

Hyaluronic acid, low endotoxin (Hyaluronan, low endotoxin) is a biopolymer composed of repeating disaccharide units containing low levels of endotoxin. Hyaluronic acid is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid activates PI3K-Akt signaling. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid can lubricate the corneal endothelium. Hyaluronic acid can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991277

QX-004N HS-20137	Interleukin Related	Inflammation/Immunology
QX-004N (HS-20137) is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). QX-004N is promising for research of immune system diseases and diseases of digestive system .

HY-P991276

FM-303	Interleukin Related	Inflammation/Immunology
FM-303 is a monoclonal antibody inhibitor targeting interleukin-23 (IL-23). FM-303 is promising for research of immune system diseases and diseases of digestive system .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16736

Alpinenone	Structural Classification Terpenoids Sesquiterpenes Plants Alpinia oxyphylla Miq. Source Classification Zingiberaceae	Others
Alpinenone is a sesquiterpene compound isolated from nootropic fruits. Alpinenone exerts anti-inflammatory activity by inhibiting overproduction of nitric oxide (NO) and has traditionally had antidiarrheal, diuretic properties. Alpinenone can be used to study inflammation-related diseases and digestive and urinary system diseases .

HY-N15354

Jujubasaponin IV	Triterpenes Structural Classification Tetracyclic Triterpenoids Terpenoids Plants Actaea simplex (DC.) Wormsk. ex Fisch. & C. A. Mey. Rhamnaceae Source Classification	Others
Jujubasaponin IV is a triterpenoid saponin compound found in Zizyphi Fructus. Animal studies have shown that Jujubasaponin IV possesses certain anti-ulcer activity, possibly through mechanisms such as enhancing the gastric mucosal barrier or inhibiting gastric acid secretion. Jujubasaponin IV can be used in research on digestive system diseases, particularly in the study of gastric ulcer mechanisms .

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diseases of digestive system

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