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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2969 Results for "
framework
" in MedChemExpress (MCE) Product Catalog:
Products (2969)
2969 Results for "framework" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W075699
CAS No.: 73202-95-6
Synonyms: Benzoic acid, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-, manganese complex
Mn-TCPP(Benzoic acid, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-, manganese complex) is a metal-organic framework (MOF).
Cat. No.: HY-108362
CAS No.: 16456-81-8
Iron(III) mesotetraphenylporphine chloride is a metal-organic framework (MOF).
Cat. No.: HY-W075516
CAS No.: 945215-37-2
ZIF-14 is a metal-organic framework (MOF).
Cat. No.: HY-W111249
CAS No.: 51839-16-8
5-Iodoisophthalic acid is a metal-organic framework (MOF).
Cat. No.: HY-W017730
CAS No.: 5156-01-4
Synonyms: Methylterephthalic acid
2-Methylterephthalic acid (Methylterephthalic acid) is a metal-organic framework (MOF).
Cat. No.: HY-W006938
CAS No.: 3906-87-4
2-Fluoroterephthalic acid is a metal-organic framework (MOF).
Cat. No.: HY-W012012
CAS No.: 586-35-6
Synonyms: 2-Bromobenzene-1,4-dicarboxylic acid
2-Bromoterephthalic acid is a metal-organic framework (MOF).
Cat. No.: HY-L0119V
3,253 compounds
Protein protein interactions (PPI) have pivotal roles in life processes. The studies showed that aberrant PPI are associated with various diseases. However, the design of modulators targeting PPI still faces tremendous challenges, such the difficult PPI interfaces for the drug design, lack of ligands reference, lack of guidance rules for the PPI modulators development and high-resolution PPI proteins structures.
The PPI Library comprises molecules of various sizes, frameworks, and shapes ranging from fragment-like entities to macrocyclic derivatives designed as secondary structure mimetics or as epitope mimetics. The designs cover β-turn / loop mimetics and α-helix mimetics. Since helices present at the interface in 62% of all protein-protein interactions. This library focused on designs including mimics with the substitution geometry of an a-helices, as well as designs that mimic the location of “hot-spot” side chains in helix-mediated PPIs.
Cat. No.: HY-L0120V
170,269 compounds
“BioDesign” approach incorporates key structural features of known pharmacologically relevant natural products (e.g. alkaloids and other secondary metabolites) into synthetically feasible medicinal chemistry scaffolds. In order to identify the privileged pharmacophores, ring systems and linkers, we have carried out statistical analysis of structural features of natural products, marketed drugs, and drug candidates.
Saturated, fused ring, spiro, and bridged systems with a tendency towards multiple chiral centers are highly privileged among natural products and marketed drugs yet these structures are very poorly represented in commercial libraries. This library addressed this market need by incorporating these privileged elements into the design of novel synthetic molecules with high molecular framework diversity, multiple stereogenic centers (≥2), and degree of saturation (Fsp3 > 0.5).
Cat. No.: HY-W856281
CAS No.: 62968-45-0
Benzenehexathiol is a metal-organic framework (MOF).
Cat. No.: HY-W998840
CAS No.: 60514-57-0
Tetradecahydrophenazine is a metal-organic framework (MOF).
Cat. No.: HY-W075680
CAS No.: 1072413-89-8
UiO 66 is a metal-organic framework (MOF).
Cat. No.: HY-W112815
CAS No.: 1488-99-9
Potassium cyamelurate trihydrate is a metal-organic framework (MOF).
Cat. No.: HY-W075638
CAS No.: 1193372-03-0
MIL 125 is a metal-organic framework (MOF).
Cat. No.: HY-W1049765
CAS No.: 1610409-52-3
Co-BTC is a metal-organic framework (MOF).
Cat. No.: HY-W1049953
CAS No.: 1351121-67-9
CHA4583 is a metal-organic framework (MOF).
Cat. No.: HY-W112144
CAS No.: 517-60-2
Synonyms: Benzenehexacarboxylic Acid
Mellitic acid (Benzenehexacarboxylic Acid) is a metal-organic framework (MOF).
Cat. No.: HY-W249556
CAS No.: 2243781-38-4
Cu-HHB is a metal-organic framework (MOF).
Cat. No.: HY-W249581
CAS No.: 1446138-63-1
NU 1000 is a metal-organic framework (MOF).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
