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Results for "

human CAIX

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) Apoptosis (2) Carbonic Anhydrase (6) Radionuclide-Drug Conjugates (RDCs) (2)
By Research Areas:	Cancer (6)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-169195

CAIX/CAXII-IN-3	Carbonic Anhydrase	Cancer
CAIX/CAXII-IN-3 (compound 11) is an inhibitor of *CAIX/CAXII, with an IC₅₀* value of less than 65 nM. CAIX/CAXII-IN-3 inhibits the proliferation of human melanoma cells .

HY-183374

NYM074	Carbonic Anhydrase Radionuclide-Drug Conjugates (RDCs)	Cancer
NYM074 is a carbonic anhydrase IX (CAIX) ligand. NYM074 binds specifically to human *CAIX* to enable targeted radionuclide delivery. NYM074 supports dual radiolabeling with ⁶⁸Ga for positron emission tomography (PET) imaging and ¹⁷⁷Lu for radionuclide applications. NYM074 can be used for the research of clear cell renal cell carcinoma .

HY-P992322

BAY-79-4620 Antibody	ADC Antibody Carbonic Anhydrase	Cancer
BAY-79-4620 Antibody is a potent and selective *CAIX* antibody with a human CAIX K_d of 3.6 nM. BAY-79-4620 Antibody yields antibody-drug conjugate (ADC) through conjugating with Monomethyl auristatin E (HY-15162) via a self-immolative enzyme-cleavable linker. BAY-79-4620 Antibody can be used for the research of cervical carcinoma, non-small cell lung carcinoma, breast carcinoma, pancreatic carcinoma, gastric carcinoma, prostate carcinoma .

HY-183590

CAIX/XII-IN-17	Carbonic Anhydrase Apoptosis	Cancer
CAIX/XII-IN-17 is a selective human carbonic anhydrase IX/XII (CA IX/XII) inhibitor with K_i values of 25.1 nM (hCA IX) and 35.2 nM (hCA XII). CAIX/XII-IN-17 induces apoptosis in pancreatic cancer cells. CAIX/XII-IN-17 can be used for the research of breast cancer, pancreatic cancer .

HY-183591

CAIX/XII-IN-18	Carbonic Anhydrase Apoptosis	Cancer
CAIX/XII-IN-18 is a selective human carbonic anhydrase IX/XII (CA IX/XII) inhibitor with K_i values of 28.1 nM (hCA IX) and 11.6 nM (hCA XII). CAIX/XII-IN-18 induces apoptosis in breast cancer cells. CAIX/XII-IN-18 can be used for the research of breast cancer, pancreatic cancer .

HY-P11737

IPM-N001	Radionuclide-Drug Conjugates (RDCs) Carbonic Anhydrase	Cancer
IPM-N001 is a carbonic anhydrase IX (CAIX) ligand with a K_d value of <0.0337 nM for hCAIX. When radio-conjugated with ⁶⁸Ga, IPM-N001 serves as a CAIX-targeted radionuclide tracer. [ ⁶⁸Ga]Ga-IPM-N001 exhibits excellent tumor uptake and significantly improves the tumor-to-background ratio in PET/CT imaging studies using OS-RC-2 tumor-bearing mice. IPM-N001 can be used for the research of clear cell renal cell carcinoma .

Cat. No.	Product Name	Target	Research Area

HY-P11737

IPM-N001	Radionuclide-Drug Conjugates (RDCs) Carbonic Anhydrase	Cancer
IPM-N001 is a carbonic anhydrase IX (CAIX) ligand with a K_d value of <0.0337 nM for hCAIX. When radio-conjugated with ⁶⁸Ga, IPM-N001 serves as a CAIX-targeted radionuclide tracer. [ ⁶⁸Ga]Ga-IPM-N001 exhibits excellent tumor uptake and significantly improves the tumor-to-background ratio in PET/CT imaging studies using OS-RC-2 tumor-bearing mice. IPM-N001 can be used for the research of clear cell renal cell carcinoma .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992322

BAY-79-4620 Antibody	ADC Antibody Carbonic Anhydrase	Cancer
BAY-79-4620 Antibody is a potent and selective *CAIX* antibody with a human CAIX K_d of 3.6 nM. BAY-79-4620 Antibody yields antibody-drug conjugate (ADC) through conjugating with Monomethyl auristatin E (HY-15162) via a self-immolative enzyme-cleavable linker. BAY-79-4620 Antibody can be used for the research of cervical carcinoma, non-small cell lung carcinoma, breast carcinoma, pancreatic carcinoma, gastric carcinoma, prostate carcinoma .

Species:	Human (6)
Tag:	His (4) Avi (3) Fc (2)
Source:	HEK293 (6)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P78396

	Carbonic Anhydrase 9 Protein, Human (HEK293, His-Avi) CA9; CAIX; CA-IX; EC 4.2.1.1; G250; MN; P54/58N; PMW1; RCC	Human	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P72863

	Carbonic Anhydrase 9 Protein, Human (HEK293, Fc) Carbonic anhydrase 9; CA-IX; P54/58N; pMW1; CA9; G250; MN	Human	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (HEK293, Fc) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72348

	Carbonic Anhydrase 9 Protein, Human (Biotinylated, HEK293, Avi-His) CA9; CA-IX; Carbonic Anhydrase IX; Carbonate dehydratase IX; G250; MN; P54/58N; RCC; RCC-associated protein G250	Human	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.

HY-P704987

	Carbonic Anhydrase 9 Protein, Human (Biotinylated, HEK293, Fc-Avi) CA9; CA-IX; Carbonic Anhydrase IX; Carbonate dehydratase IX; G250; MN; P54/58N; RCC; RCC-associated protein G250	Human	HEK293

HY-P70064

	Carbonic Anhydrase 9 Protein, Human (HEK293, His) rHuCarbonic Anhydrase 9/CA9, His; CA9; CA-IX; Carbonic Anhydrase IX; Carbonate dehydratase IX; G250; MN; P54/58N; RCC; RCC-associated protein G250	Human	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (HEK293, His) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P704425

	FITC-Labeled Carbonic Anhydrase 9 Protein, Human (HEK293, His) rHuCarbonic Anhydrase 9/CA9, His; CA9; CA-IX; Carbonic Anhydrase IX; Carbonate dehydratase IX; G250; MN; P54/58N; RCC; RCC-associated protein G250	Human	HEK293
	The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). FITC-Labeled Carbonic Anhydrase 9 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled Carbonic Anhydrase 9 protein, expressed by HEK293, with C-His labeled tag.

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Host:	Mouse (2)
Reactivity:	Human (2)
Application:	IHC-P (2) IF-Tissue (2) IHC-F (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2) Biotin (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86721

	CA9 Antibody (YA6413) CA IX; CA-IX; Carbonic anhydrase 9; CAH9_human; CAIX; Carbonate dehydratase IX; Carbonic anhydrase IX; Carbonic dehydratase; G250; Membrane antigen MN; MN; P54/58N; P54/58N; pMW1; RCC associated protein G250; RCC-associated antigen G250; Renal cell carcinoma associated antigen G250; Renal cell carcinoma-associated antigen G250.	IHC-P, IHC-F, IF-Tissue	Human
	CA9 Antibody (YA6413) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CA9.

HY-P86721A

	CA9 Antibody (YA6413)(PBS only) CA IX; CA-IX; Carbonic anhydrase 9; CAH9_human; CAIX; Carbonate dehydratase IX; Carbonic anhydrase IX; Carbonic dehydratase; G250; Membrane antigen MN; MN; P54/58N; P54/58N; pMW1; RCC associated protein G250; RCC-associated antigen G250; Renal cell carcinoma associated antigen G250; Renal cell carcinoma-associated antigen G250.	IHC-P, IHC-F, IF-Tissue	Human
	CA9 Antibody (YA6413) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CA9.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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