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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
human CDK6
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "human CDK6" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P702601
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; Cyclin Dependent Kinase 6; Cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P702687
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; Cyclin Dependent Kinase 6; Cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND1; B-Cell CLL/Lymphoma 1; Prev. PRAD1; PRAD1 Oncogene; Prev. BCL1; Parathyroid Adenomatosis 1
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-RS02392
Target:
Research Areas:
CDK6 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E70686
CDK6 is a cell-cycle kinases that regulate exit from the G1 phase of the cell cycle. CDK6 is directly involved in transcription in tumor cells and in hematopoietic stem cells. CDK6/CycD1 Recombinant Human Active Protein Kinase is an ortholog of CDK6 .
Cat. No.: HY-E70687
CDK6 is a cell-cycle kinases that regulate exit from the G1 phase of the cell cycle. CDK6 is directly involved in transcription in tumor cells and in hematopoietic stem cells. CDK6/CycD2 Recombinant Human Active Protein Kinase is an ortholog of CDK6 .
Cat. No.: HY-E70688
CDK6 is a cell-cycle kinases that regulate exit from the G1 phase of the cell cycle. CDK6 is directly involved in transcription in tumor cells and in hematopoietic stem cells. CDK6/CycD3 Recombinant Human Active Protein Kinase is an ortholog of CDK6 .
Cat. No.: HY-116204
CAS No.: 1257317-77-3
SKLB70326 is a small molecule inhibitor of cell cycle progression that induces cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. SKLB70326 is involved in downregulating cyclin-dependent kinase (CDK) 2, CDK4, and CDK6, while also activating PARP, caspase-3, caspase-9, and Bax, and downregulating Bcl-2.
Cat. No.: HY-182036
Research Areas:
KWZL-7f15 is a dual CDK6/BRD4 inhibitor with an IC50 of 31.81 nM against human CDK6. KWZL-7f15 inhibits the CDK6-RB axis and BRD4-Myc axis, and also acts as a pan-BET inhibitor. KWZL-7f15 exhibits antiproliferative activity against triple-negative breast cancer cells. KWZL-7f15 shows antitumor activity in xenograft mouse models. KWZL-7f15 can be used in studies related to triple-negative breast cancer .
Cat. No.: HY-102088
CAS No.: 77408-67-4
P18IN011 is an inhibitor that specifically targets the interaction between p18(INK4C) and CDK6, with an IC50 of 3.61 μM against mouse p18INK4C. P18IN011 relieves p18-mediated CDK6 inhibition, thereby effectively regulating the G1 phase cell cycle checkpoint. P18IN011 significantly enhances the proliferation, self-renewal and bone marrow reconstitution abilities of hematopoietic stem cells, and increases the frequency of primitive hematopoietic cells to promote cobblestone area formation. Acting specifically on p18-expressing hematopoietic cells via CDK4/6, P18IN011 not only supports the ex vivo expansion of human umbilical cord blood hematopoietic stem cells, but also maintains their long-term reconstitution capacity during in vitro culture to enable multi-lineage transplantation .
Cat. No.: HY-P701369
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; Cyclin Dependent Kinase 6; Cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND3; G1/S-Specific Cyclin-D3; Cyclin D3; D3-Type Cyclin
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701370
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; Cyclin Dependent Kinase 6; Cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND3; G1/S-Specific Cyclin-D3; Cyclin D3; D3-Type Cyclin
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701368
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; Cyclin Dependent Kinase 6; Cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND2; G1/S-Specific Cyclin D2; Cyclin D2; KIAK0002; G1/S-Specific Cyclin-D2; MPPH3
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701366
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; Cyclin Dependent Kinase 6; Cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND1; B-Cell CLL/Lymphoma 1; Prev. PRAD1; PRAD1 Oncogene; Prev. BCL1; Parathyroid Adenomatosis 1
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P70034
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDKN2C; P18-INK4c; Cyclin Dependent Kinase Inhibitor 2C; Cyclin-Dependent Kinase 6 Inhibitor P18; Cyclin-Dependent Kinase 4 Inhibitor C; Cyclin-Dependent Kinase Inhibitor 2C; P18-INK6; Cyclin-Dependent Inhibitor; INK4C; CDK6 Inhibitor P18; P18; P18-INK4C
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
