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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
human FAP
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "human FAP" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P72659A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Prolyl endopeptidase FAP; FAP; FAPA; DPPIV; SIMP; FAPalpha
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1 Cited Publications
Cat. No.: HY-P99269
CAS No.: 216669-97-5
Synonyms: BIBH 1; Anti-human FAP Recombinant Antibody
Cat. No.: HY-P99902
CAS No.: 1776942-10-9
Synonyms: FAP-IL2v; RO6874281; RG7461
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Cat. No.: HY-D2363
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FAPI-34 is a SPECT imaging agent targeting FAP. FAPI-34 specifically binds to FAP, is highly internalized by FAP-expressing cells, accumulates in FAP-expressing tumor lesions, and shows low uptake in normal tissues except the kidneys. FAPI-34 is applicable for tumor-related research .
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ARI-3099 is an oral fibroblast activation protein (FAP) inhibitor. ARI-3099 specifically inhibits the proteolytic activity of FAP and blocks the cleavage of human FGF-21 between residues P171 and S172. ARI-3099 extends the half-life of circulating human FGF-21 in mice. ARI-3099 can be used in the research of type 2 diabetes and metabolic disorders .
Cat. No.: HY-164725
CAS No.: 3023869-94-2
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Cat. No.: HY-145358
CAS No.: 2415941-98-7
FAP-PI3KI1 is a fibroblast-activated protein (FAP)-targeted PI3K inhibitor that selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells and effectively inhibits collagen synthesis and reduces collagen deposition .
Cat. No.: HY-RS04743
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FAP Human Pre-designed siRNA Set A contains three designed siRNAs for FAP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-182272
FAP-IN-9 (compound P12) is a fibroblast activation protein (FAP) inhibitor with an IC50 of 0.38 nM against human FAP. FAP-IN-9 functionally inhibits FAP activity, and its specific binding is verified by in vitro and in vivo blocking assays. FAP-IN-9 forms stable complexes and acts as a tumor-targeting agent. When labeled with 99mTc, FAP-IN-9 serves as a SPECT probe and is applicable to research related to glioblastoma .
Cat. No.: HY-P704585
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Prolyl endopeptidase FAP; FAP; FAPA; DPPIV; SIMP; FAPalpha
Cat. No.: HY-P704586
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Prolyl endopeptidase FAP; FAP; FAPA; DPPIV; SIMP; FAPalpha
Cat. No.: HY-P704587
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Prolyl endopeptidase FAP; FAP; FAPA; DPPIV; SIMP; FAPalpha
Cat. No.: HY-P991995
Synonyms: OMTX705 antibody
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Cat. No.: HY-182250
CAS No.: 2505339-87-5
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BR103354 is an orally active, selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 14 nM against hFAP. BR103354 restores the levels of phosphorylated ERK and Glut1 that are reduced by co-treatment with hFGF21 and FAP, decreases non-fasting blood glucose concentrations, improves glucose tolerance, and reduces hepatic triglyceride content. BR103354 ameliorates hepatic steatosis and hepatic fibrosis. BR103354 can be used in the research of type 2 diabetes and non-alcoholic steatohepatitis .
Cat. No.: HY-P86673
Synonyms: Prolyl endopeptidase FAP; FAPA; Fibroblast activation protein, alpha; 170 kDa melanoma membrane bound gelatinase; 170 kDa melanoma membrane-bound gelatinase; DPPIV; Fibroblast activation protein alpha; Integral membrane serine protease; SEPR_human; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE.
Cat. No.: HY-P86673A
Synonyms: Prolyl endopeptidase FAP; FAPA; Fibroblast activation protein, alpha; 170 kDa melanoma membrane bound gelatinase; 170 kDa melanoma membrane-bound gelatinase; DPPIV; Fibroblast activation protein alpha; Integral membrane serine protease; SEPR_human; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE.
Cat. No.: HY-181580
FAP Ligand 3 is a FAP ligand with a Ki value of 0.092 nM. FAP Ligand 3 acts as a tumor-retaining agent and serves as a FAP-targeted positron emission tomography (PET) tracer for tumor imaging. FAP Ligand 3 is applicable to studies related to glioma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
