18 Results for "

human FAP

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "human FAP" in MCE Product Catalog:

  • Targets Recommended:
2
2 Cited Publications
Cat. No.: HY-P72659A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibroblast Activation Protein, Alpha; Integral Membrane Serine Protease; Serine Integral Membrane Protease; Post-Proline Cleaving Enzyme; FAPA; Surface-Expressed Protease
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P99269
CAS No.: 216669-97-5
Synonyms: BIBH 1; Anti-human FAP Recombinant Antibody

Target:  

FAP

Research Areas:  

Cancer

Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targets fibroblast activation protein (FAP). Sibrotuzumab can be used for the research of colorectal cancer and non-small cell lung cancer (NSCLC) .
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1
1 Cited Publications
Cat. No.: HY-P70039
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTCF; CFAP108; CCCTC-Binding Factor; FAP108; Transcriptional Repressor CTCF; CCCTC-Binding Factor (Zinc Finger Protein); 11-Zinc Finger Protein; 11 Zinc Finger Transcriptional Repressor; CTCFL Paralog; MRD21
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P99902
CAS No.: 1776942-10-9
Synonyms: FAP-IL2v; RO6874281; RG7461

Target:  

Interleukin Related

Research Areas:  

Cancer

Simlukafusp alfa (FAP-IL2v) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAPα) and an IL-2 variant that only binds IL-2Rβγ. Isotype: human IgG1 .
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Cat. No.: HY-125366
CAS No.: 1432499-49-4
Purity:  ≥90.0%
Target:  

FAP

Research Areas:  

Metabolic Disease

ARI-3099 is an oral fibroblast activation protein (FAP) inhibitor. ARI-3099 specifically inhibits the proteolytic activity of FAP and blocks the cleavage of human FGF-21 between residues P171 and S172. ARI-3099 extends the half-life of circulating human FGF-21 in mice. ARI-3099 can be used in the research of type 2 diabetes and metabolic disorders .
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Cat. No.: HY-164725
CAS No.: 3023869-94-2
Research Areas:  

Cancer

FAPI-mFS is a selective fibroblast activation protein (FAP) inhibitor with an IC50 of 0.0014 μM against human FAP. Through its covalent binding property with FAP, FAPI-mFS enhances its uptake and retention time in cancer cells. When radiolabeled with 68Ga, FAPI-mFS serves as a PET/CT imaging agent with superior tumor-to-background tissue contrast and lesion detection capability. When radiolabeled with 177Lu or 225Ac, FAPI-mFS induces tumor regression and inhibition in preclinical models. FAPI-mFS can be used in studies related to cancer and radionuclide-conjugated drugs (RDC) .
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Cat. No.: HY-145358
CAS No.: 2415941-98-7
Target:  

PI3K

Research Areas:  

Cancer

FAP-PI3KI1 is a fibroblast-activated protein (FAP)-targeted PI3K inhibitor that selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells and effectively inhibits collagen synthesis and reduces collagen deposition .
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Cat. No.: HY-RS04743
Research Areas:  

Others

FAP Human Pre-designed siRNA Set A contains three designed siRNAs for FAP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-184826
CAS No.: 2639365-68-5
Target:  

FAP

Research Areas:  

Inflammation/Immunology Cancer

FAP Ligand-4 is an FAP inhibitor with an IC50 of 20.2 nM for human FAP. FAP Ligand-4 can be used in cancer and inflammation-related studies .
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Cat. No.: HY-182272
Target:  

FAP

Research Areas:  

Cancer

FAP-IN-9 (compound P12) is a fibroblast activation protein (FAP) inhibitor with an IC50 of 0.38 nM against human FAP. FAP-IN-9 functionally inhibits FAP activity, and its specific binding is verified by in vitro and in vivo blocking assays. FAP-IN-9 forms stable complexes and acts as a tumor-targeting agent. When labeled with 99mTc, FAP-IN-9 serves as a SPECT probe and is applicable to research related to glioblastoma .
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Cat. No.: HY-P704585
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibrobla
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77521
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibrobla
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78121
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibrobla
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704586
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibrobla
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704587
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibrobla
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P991995
Synonyms: OMTX705 antibody

Target:  

ADC Antibodies FAP

Research Areas:  

Cancer

OMTX005 (OMTX705 antibody) is a humanized anti-FAP IgG1 monoclonal antibody that specifically binds to human (EC50: 0.33 nM)/mouse (EC50: 0.14 nM) FAP proteins and FAP-positive cells. OMTX005 exhibits no cytotoxicity when used alone and fails to induce an increase in caspase 3/7 activity in relevant cells. OMTX005 can be used to synthesize the ADC molecule OMTX705 for tumor research .
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Cat. No.: HY-P86673
Synonyms: Prolyl endopeptidase FAP; FAPA; Fibroblast activation protein, alpha; 170 kDa melanoma membrane bound gelatinase; 170 kDa melanoma membrane-bound gelatinase; DPPIV; Fibroblast activation protein alpha; Integral membrane serine protease; SEPR_human; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE.

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P86673A
Synonyms: Prolyl endopeptidase FAP; FAPA; Fibroblast activation protein, alpha; 170 kDa melanoma membrane bound gelatinase; 170 kDa melanoma membrane-bound gelatinase; DPPIV; Fibroblast activation protein alpha; Integral membrane serine protease; SEPR_human; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE.

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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