12 Results for "

human gingival fibroblasts

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "human gingival fibroblasts" in MCE Product Catalog:

5
5 Cited Publications
製品番号: HY-A0020
CAS 番号: 104121-92-8
別名: ED-71; 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3
Eldecalcitol (ED-71) is an orally active vitamin D3 analogue, inhibits bone resorption and increases bone mineral density. Eldecalcitol (ED-71) displays anti-tumor effect and inhibits cell proliferation, migration and induces apoptosis by suppressing GPx-1 .
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製品番号: HY-W024604
CAS 番号: 22748-16-9
別名: 4,4-Dimethylcyclopent-2-enone
4,4-Dimethyl-2-cyclopenten-1-one (4,4-Dimethylcyclopent-2-enone) is a β-unsubstituted cyclic α,β-unsaturated ketone and anticancer agent. 4,4-Dimethyl-2-cyclopenten-1-one does not activate Caspase 3, 8 or 9, nor does it induce internucleosomal DNA fragmentation. 4,4-Dimethyl-2-cyclopenten-1-one exhibits anticancer activity against oral squamous cell carcinoma and promyelocytic leukemia .
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製品番号: HY-P11170
CAS 番号: 3002053-77-9
Target:  

Fungal

研究分野:  

Infection

D-Cateslytin is an antimicrobial peptide that exhibits potent inhibition activity against Candida albicans (MIC = 2.9 μM). D-Cateslytin can rapidly enter C. albicans, and shows no cytotoxicity to human gingival fibroblasts, and is stable in saliva. D-Cateslytin can be used for research on Candida albicans related diseases, such as oral candidosis .
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製品番号: HY-N4298
CAS 番号: 102067-92-5
Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts .
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製品番号: HY-W207699
CAS 番号: 27052-20-6
MAO-B-IN-46 (Compound 16) is a selective hMAO-B inhibitor (IC50: 26.8 nM), with weak activity against hMAO-A (IC50: 7.2054 μM). MAO-B-IN-46 (Compound 8) also acts as an α-amylase inhibitor (IC50: 19.46 μM). MAO-B-IN-46 exhibits certain neuroprotective effects and shows no significant toxicity to human gingival fibroblasts and SH-SY5Y cells. Additionally, MAO-B-IN-46 can scavenge DPPH and ABTS free radicals, with IC50 values of 17.86 μM and 17.71 μM, respectively. MAO-B-IN-46 can be used in the research of neurodegenerative diseases such as Parkinson's disease, diabetes, and diseases related to oxidative stress resistance .
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製品番号: HY-A0020R
CAS 番号: 104121-92-8
別名: ED-71 (Standard); 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3 (Standard)
Eldecalcitol (Standard) is the analytical standard of Eldecalcitol. This product is intended for research and analytical applications. Eldecalcitol (ED-71) is an orally active vitamin D3 analogue, inhibits bone resorption and increases bone mineral density. Eldecalcitol (ED-71) displays anti-tumor effect and inhibits cell proliferation, migration and induces apoptosis by suppressing GPx-1 .
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製品番号: HY-N13286
CAS 番号: 51971-09-6
Glycozolidal (compound 12) is a carbazole alkaloid with antibacterial activity against P. gingivalis. Glycozolidal is cytotoxic against human gingival fibroblasts (HGFs) and monocytes (U937) in vitro with IC50 values ​​of 120.86 µg/mL and 97.74 µg/mL, respectively .
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製品番号: HY-136727A
Target:  

Caspase Apoptosis

研究分野:  

Cancer

Ac-LEVD-CHO (TFA) is an inhibitor of caspase-4. Ac-LEVD-CHO (TFA) can inhibit the expression and secretion of IL-1α expression as well as the activation of caspase-4 induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts. Ac-LEVD-CHO (TFA) can also reduce the apoptosis due to the expression of the dominant negative adenoviral RNA-dependent protein kinase in A549 and PC3 cancer cell lines .
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製品番号: HY-N17854
CAS 番号: 356785-71-2
3β-O-α-L-Arabinopyranosylsiaresinolic acid 28-O-β-D-glucopyranosyl ester is a triterpene glycoside found in the roots of Sanguisorba officinalis. 3β-O-α-L-Arabinopyranosylsiaresinolic acid 28-O-β-D-glucopyranosyl ester is non-cytotoxic and does not exhibit cytotoxic activity against human oral squamous cell carcinoma cells or normal human gingival fibroblasts .
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製品番号: HY-N17633
CAS 番号: 95378-08-8
Mulberrofuran L is a 2-arylbenzofuran compound. Mulberrofuran L exhibits certain cytotoxicity against tumor cells. Mulberrofuran L can be used in tumor research .
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製品番号: HY-N17359
CAS 番号: 329319-21-3
Mulberrofuran W is a 2-arylbenzofuran with a farnesyl group that exists in the root bark of Morus mongolica. It also acts as a cytotoxic agent with low cytotoxicity and weak tumor specificity .
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製品番号: HY-126443A
CAS 番号: 1352296-65-1
Target:  

Fungal

研究分野:  

Infection

Antifungal agent 173 is an orally active antifungal (fungal) agent. Antifungal agent 173 disrupts fungal cell membrane integrity, inhibits yeast-hypha transition in Candida species, and suppresses biofilms. Antifungal agent 173 prevents mouse mortality in a mouse model of systemic candidiasis and reduces tongue lesions in a mouse model of oropharyngeal candidiasis. Antifungal agent 173 is applicable to research related to candidiasis .
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