18 Results for "

leucocyte

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "leucocyte" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P9934
CAS No.: 143653-53-6
Synonyms: C7E3

Target:  

Integrin

Domaines de recherche:  

Cardiovascular Disease

Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .
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1
1 Cited Publications
Cat. No.: HY-N0307
CAS No.: 114902-16-8
Ciwujianoside B is an orally active, blood-brain barrier penetrable radioprotective agent and memory enhancer. Ciwujianoside B reduces radiation-induced DNA damage, cell cycle arrest and apoptosis, downregulates NF-κB and the Bax/Bcl-2 ratio, and enhances the proliferative capacity of bone marrow cells. Ciwujianoside B enhances object recognition memory in normal mice and induces dendritic extension in primary cultured cortical neurons. Ciwujianoside B can be used in studies related to hematopoietic system radiation injury and memory enhancement .
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Cat. No.: HY-103445
CAS No.: 344930-95-6
Pureté:  ≥98.0%
Target:  

Elastase

Domaines de recherche:  

Cardiovascular Disease

SSR69071 is a potent, orally active and selective inhibitor of neutrophil elastase. SSR69071 reduces myocardial infarct size following ischemia-reperfusion injury . SSR69071 displays a higher affinity for human elastase (Ki=0.0168 nM) than for rat (Ki=3 nM), mouse (Ki=1.8 nM), and rabbit (Ki= 58 nM) elastases .
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Cat. No.: HY-N4148
CAS No.: 108648-07-3
Purpureaside C, phenolic glycoside, is a minichromosome maintenance complex component 6 (MCM6) inhibitor. Purpureaside C binds to the ATP-pocket of MCM6, suppresses MCM6 protein expression in gastric cancer cells. Purpureaside C suppresses gastric cancer cell growth and induces apoptosis. Purpureaside C exerts antibacterial activity and proinflammatory activity. Purpureaside C can be used for the researches of gastric cancer, bacterial infection and inflammation .
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Cat. No.: HY-N3270
CAS No.: 3187-58-4
Methyl orsellinate acts as an antiviral agent and insecticide. Methyl orsellinate exhibits enzyme inhibitory activity, with an IC50 of 59.6 µM against porcine leukocyte 5-lipoxygenase (5-LOX); it inhibits soybean 15-lipoxygenase (15-LOX), and shows weak inhibitory activity against acetylcholinesterase (AChE) and glutathione S-transferase (GST). Methyl orsellinate displays contact toxicity against adult Drosophila suzukii. Methyl orsellinate shows anti-HSV-1 activity. Methyl orsellinate can be used in studies related to *Drosophila suzukii* infestation and HSV-1 infection .
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Cat. No.: HY-A0235
CAS No.: 55300-29-3
Synonyms: Stakane
Antrafenine (Stakane) is a derivative of 2-(quinolin-4-ylamino) benzoate, and is an orally active anti-inflammatory and analgesic agent. Antrafenine protects mammalian epithelial cells from cell death upon exposure to influenza A virus A/WSN/33 (H1N1). Antrafenine inhibits carrageenan-induced paw swelling in rats, and reduces exudate volume and total leukocyte infiltration in carrageenan- and calcium pyrophosphate dihydrate crystal-induced pleurisy in rats. Antrafenine can be used in studies related to influenza and pseudogout .
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Cat. No.: HY-D1633
CAS No.: 126938-14-5
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
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Cat. No.: HY-100397
CAS No.: 51798-45-9
Pureté:  85.00%
Category:  

Natural Products

Target:  

Elastase

Elastatinal is a potent and competitive inhibitor of elastase, with a Ki of 0.21 μM. Elastatinal more potently inhibits pancreatic elastase versus leucocyte elastase. Elastatinal shows no activity on human leucocyte chymotrypsin-like protease .
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Cat. No.: HY-103158
CAS No.: 134470-38-5
Target:  

Lipoxygenase

Domaines de recherche:  

Others

BW B70C is a potent, selective and orally activearachidonic acid 5-lipoxygenase inhibitor. BW B70C inhibits both acute and allergic bronchoconstriction and late-phase eosinophil accumulation subsequent to allergen inhalation in guinea-pigs. BW B70C prevents leukotriene C4 synthesis and reduces leucocyte migration to the airways lumen as well as albumin microvascular leakage. BW B70C has the potential for the research of anti-asthma agent .
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Cat. No.: HY-P990190

Target:  

MHC

Domaines de recherche:  

Others

Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) is a mouse-derived IgG2b κ type antibody inhibitor, targeting to Swine MHC Class I. Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) reacts with the swine leucocyte antigen (SLA) class I. Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) can be used for the research of flow cytometry experiments .
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Cat. No.: HY-P1901
CAS No.: 872036-64-1
Target:  

Insulin Receptor

Domaines de recherche:  

Metabolic Disease

Insulin alpha-chain (1-13) is a human leucocyte antigen (HLA)-DR4-restricted epitope comprising the first 13 amino acids of the insulin A-chain .
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Cat. No.: HY-126988
CAS No.: 70857-49-7
Synonyms: α-MAPI
Target:  

Elastase

Domaines de recherche:  

Others

SP-Chymostatin B (α-MAPI) is a strong inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases such as cathepsins A,B,C, H, and L. SP-Chymostatin B weakly inhibits human leucocyte elastase .
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Cat. No.: HY-W009640
CAS No.: 2210-63-1
Target:  

Drug Derivative COX

Domaines de recherche:  

Inflammation/Immunology

Mofebutazone is a pyrazolidinedione non-steroidal anti-inflammatory agent (NSAID). Mofebutazone exhibits weak COX inhibition, no effect on LOX, and slightly suppresses the percentage of leukocyte phagocytosis in vitro. Mofebutazone can be used in research related to soft tissue rheumatism .
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Cat. No.: HY-W009640A
CAS No.: 41468-34-2
Target:  

Drug Derivative COX

Domaines de recherche:  

Inflammation/Immunology

Mofebutazone sodium is a pyrazolidinedione non-steroidal anti-inflammatory agent (NSAID). Mofebutazone sodium exhibits weak COX inhibition, no effect on LOX, and slightly suppresses the percentage of leukocyte phagocytosis in vitro. Mofebutazone sodium can be used in research related to soft tissue rheumatism .
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Cat. No.: HY-121683A
CAS No.: 3163-37-9
Synonyms: (E/Z)-16:1 Aldehyde
Domaines de recherche:  

Metabolic Disease

2-Hexadecenal, a long-chain fatty aldehyde, is a byproduct of sphingolipid metabolism, involved in cytoskeletal reorganization, DNA damage, and apoptosis. 2-Hexadecenal regulates ROS production and induces apoptosis in polymorphonuclear leucocytes.
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Cat. No.: HY-W870794
CAS No.: 31793-07-4
Synonyms: SU 21524
Pirprofen (SU 21524) is an orally active non-steroidal anti-inflammatory agent. pirprofen is a reversible prostaglandin synthetase inhibitor. Pirprofen inhibits leucocyte chemotaxis. Pirprofen shows anti-inflammatory, analgesic, antipyretic, ulcerogenic activities. Pirprofen inhibits the secondary phase of platelet aggregation induced by Collagen and Arachidonic acid (HY-109590). Pirprofen induces hepatitis .
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Cat. No.: HY-183447
CAS No.: 101311-04-0
Duartin is an isoflavan that exists in the heartwood of Dalbergia odorifera T. Chen, Machaerium opacum, and Machaerium villosum Vog. Duartin shows no obvious inhibitory effect on prostaglandin biosynthesis, fails to alleviate rat paw edema induced by carrageenan, dextran, or histamine, and cannot inhibit carrageenan-induced pleurisy in rats, reduce exudate volume, or suppress leukocyte migration .
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Cat. No.: HY-P84941
Synonyms: Antigen Presenting Molecule antibody; Cw*1701 antibody; D6S204 antibody; FLJ27082 antibody; HLA A antibody; HLA B antibody; HLA C antibody; HLA class 1 A antibody; HLA class 1 B antibody; HLA class 1 C antibody; HLA JY3 antibody; HLAA antibody; HLAB antibody; HLAC antibody; HLC C antibody; Human leucocyte Antigen C antibody; Major Histocompatibility Complex Class I A antibody; Major Histocompatibility Complex Class I B antibody; Major Histocompatibility Complex Class I C antibody; Major histocompatibility complex, class I, A + B + C antibody; MHC class I antigen A*1 antibody; MHC Class I Antigen antibody; MHC class I antigen B*7 antibody; MHC class I antigen Cw*1 antibody; MHC class I HLA A antibody; MHC class I HLA B antibody; MHC class I HLA C antibody; MHC HLA ABC antibody; PSORS1 antibody

Host:  

Mouse

Application:  

ICC/IF, FC

Reactivity:  

Human

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