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Results for "

light-mediated

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By Targets:	Bacterial (1) Biochemical Assay Reagents (1) Endogenous Metabolite (1) Environmental Pollutants (1) Fluorescent Dye (1) MOFs (1) Parasite (1) TRP Channel (1)
By Research Areas:	Infection (2) Neurological Disease (1)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12809

Optovin 1 Publications Verification	TRP Channel	Neurological Disease
Optovin is a reversible photoactivated TRPA1 ligand that enables light-mediated neuronal excitation. Optovin activates TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues .

HY-129959

Aluminum phthalocyanine chloride AlClPc	Environmental Pollutants Parasite MOFs	Infection
Aluminum phthalocyanine chloride is a photosensitizer that effectively inhibits the parasite Leishmania amazonensis (the causative agent of cutaneous leishmaniasis) by light-mediated cytolysis. Aluminum phthalocyanine chloride causes parasite morphology and cytolysis of isolated amasilians, while higher photosensitizer concentrations and light intensities are required to induce lysis of mammalian cells. Aluminum phthalocyanine chloride lyses parasites within infected J774 macrophages and can be used to further investigate the study of leishmaniasis .

HY-W075731

(Ir[dF(F)ppy]2(dCF3))PF6	Biochemical Assay Reagents	Others
(Ir[dF (F) ppy]₂ (dCF₃)) PF₆ is a cyclometalated iridium (III) complex that is used in visible light-mediated photocatalytic organic transformations .

HY-N18050

Petrobactin	Endogenous Metabolite Bacterial	Infection
Petrobactin is a photoreactive siderophore. Petrobactin can be produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. Petrobactin can be synthesized by Bacillus anthracis str. Sterne under conditions of iron starvation. Petrobactin readily undergoes a light-mediated decarboxylation reaction when bound to Fe(III) .

HY-W034053

Ir[p-F(Me)ppy]2(dtbbpy)PF6	Fluorescent Dye	Others
Ir[p-F (Me) ppy]₂ (dtbbpy) PF₆ is a cyclometalated iridium (III) complex. Ir[p-F (Me) ppy]₂ (dtbbpy) PF₆ absorbs visible light (460 nm) to form a long-lived charge-separated excited state. Ir[p-F (Me) ppy]₂ (dtbbpy) PF₆ is applicable to visible light-mediated photocatalytic organic transformation reactions .

Cat. No.	Product Name	Type

HY-129959

Aluminum phthalocyanine chloride AlClPc	Fluorescent Dye
Aluminum phthalocyanine chloride is a photosensitizer that effectively inhibits the parasite Leishmania amazonensis (the causative agent of cutaneous leishmaniasis) by light-mediated cytolysis. Aluminum phthalocyanine chloride causes parasite morphology and cytolysis of isolated amasilians, while higher photosensitizer concentrations and light intensities are required to induce lysis of mammalian cells. Aluminum phthalocyanine chloride lyses parasites within infected J774 macrophages and can be used to further investigate the study of leishmaniasis .

Aluminum phthalocyanine chloride

AlClPc

Fluorescent Dye

Aluminum phthalocyanine chloride is a photosensitizer that effectively inhibits the parasite Leishmania amazonensis (the causative agent of cutaneous leishmaniasis) by light-mediated cytolysis. Aluminum phthalocyanine chloride causes parasite morphology and cytolysis of isolated amasilians, while higher photosensitizer concentrations and light intensities are required to induce lysis of mammalian cells. Aluminum phthalocyanine chloride lyses parasites within infected J774 macrophages and can be used to further investigate the study of leishmaniasis .

HY-W075731

(Ir[dF(F)ppy]2(dCF3))PF6	Fluorescent Dye
(Ir[dF (F) ppy]₂ (dCF₃)) PF₆ is a cyclometalated iridium (III) complex that is used in visible light-mediated photocatalytic organic transformations .

HY-W034053

Ir[p-F(Me)ppy]2(dtbbpy)PF6	Fluorescent Dye
Ir[p-F (Me) ppy]₂ (dtbbpy) PF₆ is a cyclometalated iridium (III) complex. Ir[p-F (Me) ppy]₂ (dtbbpy) PF₆ absorbs visible light (460 nm) to form a long-lived charge-separated excited state. Ir[p-F (Me) ppy]₂ (dtbbpy) PF₆ is applicable to visible light-mediated photocatalytic organic transformation reactions .

Petrobactin	Structural Classification Marine natural products Phenols Polyphenols Marine microorganism Source Classification	Endogenous Metabolite Bacterial
Petrobactin is a photoreactive siderophore. Petrobactin can be produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. Petrobactin can be synthesized by Bacillus anthracis str. Sterne under conditions of iron starvation. Petrobactin readily undergoes a light-mediated decarboxylation reaction when bound to Fe(III) .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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light-mediated

Inhibitors & Agonists

Fluorescent Dye

NaturalProducts

Natural
Products