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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
lysine acetyltransferase
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "lysine acetyltransferase" in MCE Product Catalog:
13
13 Publications Verification
Research Areas:
α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC50 of 9 μM. α-NETA is a potent ALDH1A1 (IC50=0.04 µM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibits cholinesterase (ChE; IC50=84 µM) and acetylcholinesterase (AChE; IC50=300 µM). α-NETA has anti-cancer activity .
3
3 Cited Publications
Cat. No.: HY-W015239
CAS No.: 605-62-9
Target:
Research Areas:
KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC50s of 141 μM (KAT8), 221 μM (KAT2B), 106 μM (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases .
1
1 Cited Publications
Cat. No.: HY-P71707
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT5; 60 KDa Tat-Interactive Protein; Prev. HTATIP; Protein Lactyltransferase KAT5; TIP60; K(lysine) acetyltransferase 5; HTATIP1; CPLA(2)-Interacting Protein; CPLA2; K-acetyltransferase 5; PLIP; ZC2HC5; ESA1; HIV-1 Tat Interactive Protein; Protein 2-Hydr
Species:
Human
Source:
E. coli
IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent .
Cat. No.: HY-P1958
CAS No.: 667899-73-2
Target:
Research Areas:
Cat. No.: HY-177445
CAS No.: 2901797-38-2
Research Areas:
KAT6-IN-4 (Compound Example 2) is a selective lysine acetyltransferase 6 (KAT6) inhibitor. KAT6-IN-4 suppresses transcription of oncogenes like ERα. KAT6-IN-4 demonstrates potent antitumor efficacy in ER +/HER2 - breast cancer xenografts. KAT6-IN-4 is promising for research of KAT6-driven malignancies (e.g., breast cancer, NSCLC) .
Cat. No.: HY-139861
CAS No.: 2725036-10-0
Research Areas:
CBP/p300-IN-14 is a potent inhibitor of CBP/EP300 (lysine acetyltransferase) with an IC50 of 3.3 nM (extracted from patent WO2021213521A1, compound 27) .
Cat. No.: HY-W614583
CAS No.: 858186-27-3
Target:
Research Areas:
4-Aminonaphthalen-1-yl acetate is a 4-amino-1-naphthol derivative and a negative control reagent for lysine (K) acetyltransferase KAT8. 4-Aminonaphthalen-1-yl acetate shows no activity against KAT8 .
Cat. No.: HY-CE00983A
Synonyms: 4-Pentynoyl-CoA TFA
Cat. No.: HY-P702890
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CREBBP; CREB-Binding Protein; Prev. RSTS; CREB Binding lysine acetyltransferase; CBP; Rubinstein-Taybi Syndrome; CREB Binding Protein; Histone acetyltransferase; KAT3A; CREBBP Protein; Protein-lysine acetyltransferase CREBBP; RSTS1; Histone lysine Acetylt
Species:
Human
Source:
E. coli
Cat. No.: HY-P702891
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CREBBP; CREB-Binding Protein; Prev. RSTS; CREB Binding lysine acetyltransferase; CBP; Rubinstein-Taybi Syndrome; CREB Binding Protein; Histone acetyltransferase; KAT3A; CREBBP Protein; Protein-lysine acetyltransferase CREBBP; RSTS1; Histone lysine Acetylt
Species:
Human
Source:
E. coli
Cat. No.: HY-P702959
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CREBBP; CREB-Binding Protein; Prev. RSTS; CREB Binding lysine acetyltransferase; CBP; Rubinstein-Taybi Syndrome; CREB Binding Protein; Histone acetyltransferase; KAT3A; CREBBP Protein; Protein-lysine acetyltransferase CREBBP; RSTS1; Histone lysine Acetylt
Species:
Human
Source:
E. coli
Cat. No.: HY-P702904
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT2B; K(lysine) acetyltransferase 2B; Prev. PCAF; Histone Acetylase PCAF; P/CAF; GCN5L; P300/CBP-Associated Factor; GCN5; Spermidine acetyltransferase KAT2B; CREBBP-Associated Factor; Histone acetyltransferase KAT2B; CAF; lysine acetyltransferase 2B; His
Species:
Human
Source:
E. coli
Cat. No.: HY-P704206
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KAT6B; K(lysine) acetyltransferase 6B; Prev. MYST4; MOZ-Related Factor; MOZ2; ZC2HC6B; Querkopf; MYST-4; Morf; Histone acetyltransferase MYST4; Qkf; Histone acetyltransferase MORF; MYST Histone acetyltransferase (Monocytic Leukemia) 4; Histone Acetyltrans
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-121009
CAS No.: 748777-47-1
Research Areas:
CCT077791 is a PCAF (IC50: 7.3 μM (FlashPlate); 2.2 μM (Filter assay)) and p300 histone acetyltransferase inhibitor. CCT077791 reduces total acetylation of histones H3 and H4, levels of specific acetylated lysine marks, and acetylation of α-tubulin. CCT077791 can be used in the research of colorectal cancer .
Cat. No.: HY-P702892
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: EP300; Histone Crotonyltransferase P300; EP300 lysine acetyltransferase; Histone Butyryltransferase P300; P300; Protein Lactyltransferas P300; Histone acetyltransferase P300; E1A-Associated Protein P300; E1A Binding Protein P300; P300 HAT; KAT3B; E1A-Bind
Species:
Human
Source:
E. coli
Cat. No.: HY-P702963
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EP300; Histone Crotonyltransferase P300; EP300 lysine acetyltransferase; Histone Butyryltransferase P300; P300; Protein Lactyltransferas P300; Histone acetyltransferase P300; E1A-Associated Protein P300; E1A Binding Protein P300; P300 HAT; KAT3B; E1A-Bind
Species:
Mouse
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
