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Results for "

marine fungus

" in MedChemExpress (MCE) Product Catalog:

38

Inhibitors & Agonists

2

Peptides

36

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W004261
    Nonadecanoic acid

    		Endogenous Metabolite Interleukin Related Ser/Thr Protease Thrombin Others
    Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis. Nonadecanoic acid can be isolated from several sources, including fungus, plant, and marine sponge. Nonadecanoic acid exhibits inhibitory effects on fibrinolysis and plasmin activity. Nonadecanoic acid produced from Streptomyces is an anti-tumor agent and inhibits IL-12 production .
    Nonadecanoic acid
  • HY-W001084
    Methyl 4-hydroxyphenylacetate

    		Others Infection Cancer
    Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .
    Methyl 4-hydroxyphenylacetate
  • HY-N8571
    6-Methoxyflavonol

    		Others Others
    6-Methoxyflavonol (Compound 15) is a natural flavone isolated from the marine-derived fungus Aspergillus candidus .
    6-Methoxyflavonol
  • HY-113972
    Methyl mycophenolate

    		Others Inflammation/Immunology
    Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae .
    Methyl mycophenolate
  • HY-N10203
    Rostratin A

    		Endogenous Metabolite Cancer
    Rostratin A is a cytotoxic disulfide found in the marine-derived fungus Exserohilum rostratum. Rostratin A shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with an IC50 of 8.5 μg/mL .
    Rostratin A
  • HY-N12726
    Halociline

    		p38 MAPK MMP Infection Inflammation/Immunology Cancer
    Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities .
    Halociline
  • HY-N12386
    SIRT1 activator 1

    		Sirtuin Cancer
    SIRT1 activator 1(compound 3) is a derivative of marine compound xyloallenoide A isolated from the mangrove fungus Xylaria sp.SIRT1 activator 1 shows angiogenic activities in zebrafish. SIRT1 activator 1 protects hEPC against AngII-induced senescence by increasing SIRT1 expression levels and balancing the AMPK/Akt signaling pathway .
    SIRT1 activator 1
  • HY-N10208
    Aspericin C

    		Endogenous Metabolite Cancer
    Aspericin C is a pyran derivative found in the marine-derived fungus Rhizopus sp. 2-PDA-61. Aspericin C shows cytotoxic activities against P388, A549, HL-60, and BEL-7420 cell lines (IC50=14.6, 7.1, 61.4, and 24.2 μM, respectively) .
    Aspericin C
  • HY-N16066
    Candidusin A

    CHNQD-0803

    		 AMPK Apoptosis NF-κB TNF Receptor Inflammation/Immunology
    Candidusin A (CHNQD-0803) (Compound 4) is a AMPK activator with a KD of 47.28 nM. Candidusin A can be isolated from marine fungus Aspergillus candidus. Candidusin A has cytotoxic activity and induces apoptosis in human prostate cancer cells (22Rv1, PC-3 and LNCaP cells). Candidusin A reduces adipogenesis genes expression and fat deposition, negatively regulates the NF-κB-TNFα inflammatory axis to suppress inflammation, and ameliorates liver injury and fibrosis. Candidusin A can be used for non-alcoholic steatohepatitis (NASH) research .
    Candidusin A
  • HY-W001084R
    Methyl 4-hydroxyphenylacetate (Standard)

    		Reference Standards Others
    Methyl 4-hydroxyphenylacetate (Standard) is the analytical standard of Methyl 4-hydroxyphenylacetate (HY-W001084). This product is intended for research and analytical applications. Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .
    Methyl 4-hydroxyphenylacetate (Standard)
  • HY-N16403
    Aspergillusidone F

    		Cytochrome P450 Endogenous Metabolite Bacterial Insecticide Fungal Infection Cancer
    Aspergillusidone F is a Depsidone and antibacterial agent. Aspergillusidone F can be isolated from a marine fungus Aspergillus unguis. Aspergillusidone F potently inhibits Aromatase with an IC50 of 0.5 μM. Aspergillusidone F exhibits antibacterial activity against Pseudomonas aeruginosa and Methicillin (HY-121544)-resistant Staphylococcus aureus. Aspergillusidone F exhibits potent larvicidal activity against Artemia salina larvae, with an LC50 value of 12.8 μM. Aspergillusidone F exhibits anticancer activity against intrahepatic cholangiocarcinoma, non-small cell lung cancer, and acute lymphoblastic leukemia .
    Aspergillusidone F
  • HY-N7569
    Demethoxyfumitremorgin C

    		Apoptosis Caspase PPAR Cancer
    Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage .
    Demethoxyfumitremorgin C
  • HY-N12179
    Brevianamide M

    		Bacterial Others
    Brevianamide M (compound 4) is a metabolite of Aspergillus versicolor. This is an endophytic fungus isolated from the marine brown alga Sargassum. Brevianamide M has antimicrobial activity against Escherichia coli and Staphylococcus aureus .
    Brevianamide M
  • HY-135422
    Nidulin

    Methylustin

    		 Bacterial Fungal Infection
    Nidulin (Methylustin) is a depsidone isolated from a marine fungus Aspergillus unguis. Nidulin shows antifungal and antibacterial against pathogenetic strains, Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus and Candida albicans with inhibition zones of 9.5 mm, 9.0 mm and 9.0 mm, respectively. Nidulin exhibits potent larvicidality against brine shrimp .
    Nidulin
  • HY-N16067
    Penipanoid C

    		Epigenetic Reader Domain Inflammation/Immunology
    Penipanoid C (Compound 9) is a BRD4 inhibitor. Penipanoid C can be isolated from marine sediment-derived fungus Penicillium paneum SD-44. Penipanoid C has anti-inflammatory activity and cytotoxic activity against the SMMC-7721 cells. Penipanoid C can be used for inflammatory diseases research .
    Penipanoid C
  • HY-N16441
    Pulvic acid

    		Endogenous Metabolite Influenza Virus Infection
    Pulvic acid (Compound 3), a butenolide, is a microbial secondary metabolite. Pulvic acid can be isolated from the marine-derived fungus Aspergillus terreus Gwq-48. Pulvic acid has significant antiviral activity with an IC50 of 29.1 μg/mL for influenza A H1N1 virus. Pulvic acid can be used for influenza virus infections research .
    Pulvic acid
  • HY-N15658
    Isopatulin

    		Biochemical Assay Reagents Others
    Isopatulin can be isolated from the marine isolate of the fungus Penicillium claviforme associated with the seagrass Zostera marina .
    Isopatulin
  • HY-N10256
    Varioxepine A

    		Endogenous Metabolite Infection
    Varioxepine A is a 3H-oxepine-containing alkaloid with a new oxa-cage found in the marine algal-derived endophytic fungus Paecilomyces variotii. Varioxepine A inhibits plant pathogenic fungus Fusarium graminearum .
    Varioxepine A
  • HY-N12901
    Fiscalin C

    Ficalin C

    		 Others Others
    Fiscalin C (Ficalin C) is an alkaloid and can be isolated from Stentrophomonas maltophilia .
    Fiscalin C
  • HY-N8520
    Variculanol

    		Bacterial Infection Cancer
    Variculanol is an antimicrobial, anticancer and anti-HCV NS3/4A Protease agent which can be extracted from marine fungus Aspergillus versicolor .
    Variculanol
  • HY-N16131
    Sydonic acid

    		Drug Derivative Others
    Sydonic acid is a bisabolane-type sesquiterpenoid that can be isolated from the fungus Aspergillus sydowii BTBU20213012, which was obtained from a marine sediment sample in the Western Pacific .
    Sydonic acid
  • HY-N12165
    1,3,5,6-Tetrahydroxy-8-methylxanthone

    		Others Others
    1,3,5,6-Tetrahydroxy-8-methylxanthone (compound 8) is a dimeric 1,4-benzoquinone derivative isolated from the marine-derived fungus Penicillium genus .
    1,3,5,6-Tetrahydroxy-8-methylxanthone
  • HY-N6181
    Terrelumamide A

    		Others Endocrinology
    Terrelumamide A is a lumazine-containing peptide. Terrelumamide A is isolated from the culture broth of the marine-derived fungus Aspergillus terreus. Terrelumamide A exhibits pharmacological activity by improving insulin sensitivity. Terrelumamide A has the potential in the application of DNA sequence recognition .
    Terrelumamide A
  • HY-N8908
    2α,9α,11-Trihydroxy-6-oxodrim-7-ene

    		Others Infection
    2α,9α,11-Trihydroxy-6-oxodrim-7-ene is a natural product that can be isolated from the culture medium of the marine-derived fungus Aspergillus insuetus .
    2α,9α,11-Trihydroxy-6-oxodrim-7-ene
  • HY-N15359
    Germicidin C

    		Bacterial Infection
    Germicidin C is a microbial metabolite with antibacterial activity, which is found in the marine sponge-derived fungus Aspergillus niger. Germicidin C can inhibit the growth of various pathogenic bacteria such as Staphylococcus aureus, Escherichia coli, and Bacillus subtilis with MIC values ranging from 32 to 64 µg/mL .
    Germicidin C
  • HY-N15651
    Asperflavin

    		NO Synthase TNF Receptor Interleukin Related Inflammation/Immunology
    Asperflavin is an anti-inflammatory compound that can be produced by the marine fungus Eurotium amstelodami. Asperflavin inhibits the production of NO, PGE2, and proinflammatory cytokines, as well as the expression of inducible NOS (iNOS) in RAW 264.7 cells treated with LPS (HY-D1056). Asperflavin can be used in the study of inflammatory diseases .
    Asperflavin
  • HY-N16065
    Prenylterphenyllin

    		Bacterial Infection
    Prenylterphenyllin (Compound 1) is an antibacterial agent. Prenylterphenyllin can be isolated from marine-derived fungus Aspergillus candidus IF10. Prenylterphenyllin has cytotoxic activity against KB3-1 cells with an IC50 of 8.5 mg/mL. Prenylterphenyllin also has antibacterial activities against Xanthomonas oryzae and Erwinia amylovora with MICs of both 20 μg/mL .
    Prenylterphenyllin
  • HY-119387
    Chevalone B

    		Bacterial Infection
    Chevalone B was isolated from the ethyl acetate extract of the marine sponge-associated fungus Aspergillus similanensis. The structure of Chevalone B was confirmed by 1D and 2D NMR spectroscopy. Chevalone B showed antimicrobial activity against Gram-positive and Gram-negative bacteria, Candida albicans, and multidrug-resistant strains from the environment. Studies on Chevalone B have shown its potential value in antimicrobial applications.
    Chevalone B
  • HY-W004261R
    Nonadecanoic acid (Standard)

    		Reference Standards Endogenous Metabolite Interleukin Related Ser/Thr Protease Thrombin Others
    Nonadecanoic acid (Standard) is the analytical standard of Nonadecanoic acid. This product is intended for research and analytical applications. Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis. Nonadecanoic acid can be isolated from several sources, including fungus, plant, and marine sponge. Nonadecanoic acid exhibits inhibitory effects on fibrinolysis and plasmin activity. Nonadecanoic acid produced from Streptomyces is an anti-tumor agent and inhibits IL-12 production .
    Nonadecanoic acid (Standard)
  • HY-N1791
    3,5-Diprenyl-4-hydroxybenzaldehyde

    		Others Infection
    3, 5-diprenyl-4-hydroxybenzaldehyde is an isoprene phenyl butyl aldehyde. 3, 5-diprenyl-4-hydroxybenzaldehyde had the ability to inhibit biofilm formation in strains. 3, 5-diprenyl-4-hydroxybenzaldehyde can be used to study the potential synergistic effect of clinically relevant antibiotics .
    3,5-Diprenyl-4-hydroxybenzaldehyde
  • HY-N12561
    Pestanoid A

    		ERK p38 MAPK JNK Others
    Pestanoid A is a rearranged pimarane diterpenoid osteoclastogenesis inhibitor with an IC50 of 4.2 μM. Pestanoid A can be isolated from the marine mesophotic zone chalinidae sponge-associated fungus, Pestalotiopsis sp. NBUF145. Pestanoid A inhibits the receptor activator of NF-kB ligand-induced MAPK and NF-κB signaling by suppressing the phosphorylation of ERK1/2-JNK1/2-p38 MAPKs and NF-κB nuclear translocation. Pestanoid A can be used for the study of osteoporosis .
    Pestanoid A
  • HY-138098
    Sartorypyrone B

    		Endogenous Metabolite Cancer
    Sartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213). Sartorypyrone B exhibits strong growth inhibitory activity, having GI50s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases .
    Sartorypyrone B
  • HY-N17416
    ω-Hydroxydigitoemodin

    		Cholinesterase (ChE) Neurological Disease
    ω-Hydroxydigitoemodin is an anthraquinone derivative with anti-acetylcholinesterase activity, found in the marine fungus Trichoderma harzianum XS-20090075 .
    ω-Hydroxydigitoemodin
  • HY-P2973A
    Aspergillopepsin I (Xeno-free)

    Aspergillus acid protease (Xeno-free)

    		 Fungal Endogenous Metabolite Infection
    Aspergillopepsin I (Xeno-free) is an acid protease and aspartic protease. Aspergillopepsin I (Xeno-free) is derived from the marine fungus Aspergillus tubingensis. Aspergillopepsin I from Aspergillus tubingensis hydrolyzes glycinin, especially the 7S globulin .
    Aspergillopepsin I (Xeno-free)
  • HY-N8571R
    6-Methoxyflavonol (Standard)

    		Others Reference Standards Others
    6-Methoxyflavonol (Standard) is the analytical standard of 6-Methoxyflavonol (HY-N8571). This product is intended for research and analytical applications. 6-Methoxyflavonol (Compound 15) is a natural flavone isolated from the marine-derived fungus Aspergillus candidus .
    6-Methoxyflavonol (Standard)
  • HY-N15348
    Aphidicolins B32

    		Others Cancer
    Aphidicolins B32 is a diterpenoid compound discovered in the marine fungus Botryotinia fuckeliana, exhibiting cytotoxic activity against human bladder cancer cells. It inhibits the proliferation of T24 cells in the G0/G1 phase, with an IC50 of 27.6 μM. Aphidicolins B32 holds potential for research in the field of cancer therapy .
    Aphidicolins B32
  • HY-178398S
    Nonadecanoic acid-d3

    		Isotope-Labeled Compounds Ser/Thr Protease Interleukin Related Thrombin Endogenous Metabolite Others
    Nonadecanoic acid-d3 is the deuterium labeled Nonadecanoic acid (HY-W004261). Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis. Nonadecanoic acid can be isolated from several sources, including fungus, plant, and marine sponge. Nonadecanoic acid exhibits inhibitory effects on fibrinolysis and plasmin activity. Nonadecanoic acid produced from Streptomyces is an anti-tumor agent and inhibits IL-12 production .
    Nonadecanoic acid-d3
  • HY-N7282
    Ustusol A

    		Drug Derivative Others
    Ustusol A is a natural sesquiterpene.
    Ustusol A

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