Search Result
Results for "
near-infrared fluorescence
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
상품명 |
Target |
연구분야 |
Chemical Structure |
-
- HY-D1540
-
|
Cy 5.5 amine; Lumiprobe Cy 5.5 amine
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
|
-
-
- HY-145746
-
|
|
Fluorescent Dye
PD-1/PD-L1
|
Inflammation/Immunology
Cancer
|
|
Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .
|
-
-
- HY-D2189
-
|
IR 700DX NHS ester
|
Fluorescent Dye
|
Others
|
|
IR 700DX (IR 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye with extremely high photostability and fluorescence intensity. IR 700DX binds to biomolecules. IR 700DX has excellent water solubility, large extinction coefficient, high fluorescence quantum yield, and does not aggregate in high ionic strength buffers. IR 700DX can be used as a highly flexible photosensitizer .
|
-
-
- HY-D1872
-
|
|
Fluorescent Dye
|
Others
|
|
800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .
|
-
-
- HY-D1744
-
|
|
Fluorescent Dye
|
Others
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
|
-
-
- HY-D2365
-
|
|
Fluorescent Dye
|
Others
|
|
QSY 21 NHS is a dark quencher and an efficient energy transfer acceptor for far-red and near-infrared fluorescent probes. QSY 21 NHS operates at a wavelength range of 540-750 nm and is commonly used in FRET applications. QSY 21 NHS does not fluoresce under normal conditions. The NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. QSY 21 NHS can be conjugated with dendritic poly-L-lysine to achieve intramolecular quenching of Cy5 fluorescence .
|
-
-
- HY-D1555
-
|
Cy7 DBCO
|
Fluorescent Dye
|
Others
|
|
Cyanine7 DBCO (Cy7 DBCO) is a near-infrared fluorescent dye and an efficient bio-orthogonal quencher. Cyanine7 DBCO is formed by covalent connection of the near-infrared fluorescent dye Cy7 and the dibenzocyclooctyne (DBCO) functional group. After reacting with N3-Cy5-COOH, the fluorescence of Cy5 decreases by 90% within 90 minutes, and rapid signal attenuation can be observed within 2-5 minutes. Cyanine7 DBCO can be used for the study of deep tissue imaging and receptor-targeted therapeutic strategies .
|
-
-
- HY-159500
-
|
OTL-0078; OTL78
|
PSMA
|
Cancer
|
|
Zopocianine (OTL-0078; OTL78) is a near-infrared optical probe targeting PSMA. Zopocianine binds to PSMA on the surface of PSMA-expressing cells, enters cells via receptor-mediated endocytosis, and accumulates in acidic endosomes. Zopocianine selectively accumulates in PSMA-positive cancer tissues and enables the detection of small tumors, primary prostate tumors, and locoregional metastases. Zopocianine helps achieve negative tumor surgical margins during fluorescence-guided surgery. Zopocianine is applicable to research related to prostate cancer .
|
-
-
- HY-D2864
-
|
|
Fluorescent Dye
|
Others
|
|
Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
|
-
-
- HY-P6083
-
|
|
Biochemical Assay Reagents
|
Others
Cancer
|
|
RTSPSSR is synthesized peptide, which binds specifically to claudin-1 and visulizes the CRC tumor in mice, through near-infrared fluorescence imaging .
|
-
-
- HY-D2062
-
|
|
Fluorescent Dye
Integrin
|
Cancer
|
|
ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .
|
-
-
- HY-D1174
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine 700, a Lambdachrome laser dye, is one of the few rhodamine dyes with near infrared fluorescence. Rhodamine 700 can be used for mitochondrial staining .
|
-
-
- HY-D1450
-
|
S01448
|
Fluorescent Dye
|
Cancer
|
|
IR-1048 is a nitroreductase (NTR)-responsive near-infrared fluorescence (NIR)/photoacoustic (PA) imaging probe and photothermal agent. IR-1048 is coupled with a nitroimidazole group to form IR-1048-MZ. IR-1048-MZ is catalytically reduced by NTR in a hypoxic environment, restoring strong near-infrared absorption and fluorescence emission (NIR II window), while activating the photothermal effect. IR-1048 relies on NTR-mediated electron transfer to relieve intramolecular fluorescence quenching, achieving specific imaging and photothermal ablation of tumor hypoxic areas. IR-1048 is mainly used for high-contrast NIR II/photoacoustic imaging and photothermal therapy research and tumor diagnosis of the tumor hypoxic microenvironment .
|
-
-
- HY-D2195
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.
|
-
-
- HY-D2198
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe-PEG-NH2 (1120 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1120 nm that can be used in bioimaging .
|
-
-
- HY-N16309
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.
|
-
-
- HY-D2971
-
|
|
Fluorescent Dye
Autophagy
|
Neurological Disease
|
|
NCIC-VIS is a lysosome-targeted, viscosity-sensitive two-photon near-infrared fluorescent probe. NCIC-VIS has a rigid structure that can restrict molecular torsion, thereby increasing the fluorescence quantum yield and two-photon absorption cross-section. NCIC-VIS enables real-time imaging of the autophagy process in cells .
|
-
-
- HY-D2940
-
|
SiR650-BG
|
Fluorescent Dye
|
Others
|
SiR-SNAP (SiR650-BG) is a SiR-labeled SNAP tag near-infrared fluorescent probe (Ex/Em: 645 nm/661 nm). SiR-SNAP combines excellent optical properties, good cell membrane permeability, and environmentally sensitive fluorescence characteristics, providing a powerful tool for the dynamic study of proteins in living cells .
|
-
-
- HY-D1391
-
|
PbS/CdSe QD
|
Fluorescent Dye
|
Others
|
|
PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window .
|
-
-
- HY-D2060
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
|
-
-
- HY-D3002
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
ONOO-/O2- tracker probe is a dual-responsive near-infrared fluorescent probe. ONOO-/O2- tracker probe will only emit a strong fluorescence signal when both peroxynitrite (ONOO⁻) and superoxide anion (O₂•⁻), the two key reactive oxygen/nitrogen species, are present simultaneously. ONOO-/O2- tracker probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
|
-
-
- HY-165424
-
|
|
Fluorescent Dye
Glycosidase
|
Cardiovascular Disease
Cancer
|
|
NIR-BG2 is a near-infrared fluorescent probe targeting senescence-associated β-galactosidase (SA-β-Gal). NIR-BG2 is activated by SA-β-Gal and undergoes hydrolysis to release electrophilic quinone methide that covalently binds to surrounding proteins for in situ labeling, with a 16-fold enhancement of fluorescence signal at 709 nm . NIR-BG2 is promising for research of vivo imaging of cellular senescence .
|
-
-
- HY-D3000
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
NIR-RED ROS-H2O2 Probe is a near-infrared fluorescent probe used for detecting hydrogen peroxide (H₂O₂) and featuring dual-modal fluorescence/photoacoustic imaging capabilities. NIR-RED ROS-H2O2 Probe successfully detects the upregulated fluorescence signal of H₂O₂ in HepG2 cells and a mouse liver injury model. NIR-RED ROS-H2O2 Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
|
-
-
- HY-D1065
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
|
-
-
- HY-P991650
-
|
|
PSMA
|
Cancer
|
|
MDX1201 is a humanized monoclonal antibody targeting PSMA1/7. MDX1201 conjugated with a fluorescent dye AlexaTM488 can be used as a probe for near-infrared fluorescence imaging (NIRF) imaging of prostate cancer .
|
-
-
- HY-P5520
-
|
|
Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
|
-
-
- HY-D2968
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
DCM-ONOO is a near-infrared two-photon fluorescence probe specifically designed for real-time monitoring of the dynamic fluctuations of peroxynitrite (ONOO⁻) in epilepsy models. DCM-ONOO exhibits excellent optical properties, with a single photon excitation (Ex) of 520 nm; a single photon emission (Em) of 685 nm; a two-photon excitation of 820 nm; and a Stokes shift of 165 nm. When DCM-ONOO is combined with ONOO⁻, it shifts from 460 nm to 512 nm, and only generates a significant fluorescence response to ONOO⁻. DCM-ONOO has been successfully applied to rat epilepsy models .
|
-
-
- HY-152102
-
|
|
Fluorescent Dye
|
Cancer
|
|
BTCy is a near-infrared (NIR) fluorescence probe with polarity-responsive and cell plasma membrane-targeting properties. BTCy can be used for in vivo imaging of tumor tissue (λex = 561 nm, λem = 600-700 nm) .
|
-
-
- HY-W835383
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5.5-COOH is a sulfonated Cy5.5 fluorescent dye containing a sulfonic acid group and a carboxylic acid group. The fluorescence wavelength of Sulfo-Cy5.5-COOH is in the near-infrared region and has strong penetrating power.
|
-
-
- HY-D2279
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .
|
-
-
- HY-150978
-
|
|
Fluorescent Dye
|
Others
|
|
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .
|
-
-
- HY-D2194
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
|
-
-
- HY-P10788
-
|
|
Complement System
|
Cancer
|
|
CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer.
|
-
-
- HY-157317
-
|
|
Apoptosis
|
Cancer
|
|
Antitumor agent-126 (Compound II4) is a photoactive (IC50= 0.149) anticancer agent with significant near-infrared fluorescence emission at 650-760 nm. Antitumor agent-126 has antiproliferative activity and can induce apoptosis after laser irradiation. Antitumor agent-126 effectively inhibits tumor growth in mouse xenograft models exposed to 650 nm laser irradiation. Antitumor agent-126 can be used in cancer research .
|
-
-
- HY-159500A
-
|
OTL-0078 sodium; OTL78 sodium
|
Biochemical Assay Reagents
|
Cancer
|
|
Zopocianine sodium (OTL-0078 sodium; OTL78 sodium) is a near-infrared optical probe targeting PSMA. Zopocianine sodium binds to PSMA on the surface of PSMA-expressing cells, enters cells via receptor-mediated endocytosis, and accumulates in acidic endosomes. Zopocianine sodium selectively accumulates in PSMA-positive cancer tissues and enables the detection of small tumors, primary prostate tumors, and locoregional metastases. Zopocianine sodium helps achieve negative tumor surgical margins during fluorescence-guided surgery. Zopocianine sodium is applicable to research related to prostate cancer .
|
-
-
- HY-D3214
-
|
|
Fluorescent Dye
|
Others
|
|
NIR-Cu (Ⅱ) is a near-infrared fluorescent Cu 2+ probe. NIR-Cu (Ⅱ) enables fluorescence imaging of Cu 2+ in living mice. NIR-Cu (Ⅱ) reduces self-absorption and exhibits minimal photobleaching, thus supporting in vivo imaging applications .
|
-
-
- HY-D2970
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
Golgi-P is a near-infrared Golgi-targeted fluorescent probe specifically used for the detection of Golgi polarity in living cells and living tissues. Golgi-P exhibits a significant polarity-dependent spectral behavior, with its emission wavelength shifting redward with polarity (Ex/Em: 700 nm/780-825 nm). Golgi-P achieves near-infrared fluorescence imaging directly in the brain tissue of depressed mice. Golgi-P combines polarity sensing with Golgi-targeting functionality, providing a new tool for the molecular diagnosis of depression .
|
-
-
- HY-D3003
-
|
|
Fluorescent Dye
|
Others
|
|
M-H2S is an endoplasmic reticulum-targeted ratio-type near-infrared fluorescent probe (Ex/Em : 480 nm/560 nm) specifically designed for the detection of hydrogen sulfide (H2S) in living cells and zebrafish. M-H2S exhibits detection limit for H2S of 39.1 nM, and the fluorescence intensity ratio (F₆₅₀/F₅₆₀) within the range of 0-40 μM shows a linear relationship with the H2S concentration. M-H2S responds best under pH = 7.2 (the normal physiological pH of the endoplasmic reticulum) conditions, making it suitable for the detection of the microenvironment of the endoplasmic reticulum. M-H2S can be used to study the role of H2S in endoplasmic reticulum function, stress response, and related diseases .
|
-
-
- HY-D3234
-
|
|
Fluorescent Dye
|
Others
|
|
Cy-AP is a hypoxia-sensitive near-infrared Fluorescent probe (emission wavelength: 725 nm). Cy-AP exhibits no fluorescence under normoxic microenvironments, while under hypoxic microenvironments, its azo group is reduced, releasing strong near-infrared fluorescence with an emission at 725 nm. Cy-AP enables visualization of intracellular hypoxic status through multiple imaging modalities .
|
-
-
- HY-P10052
-
|
|
VEGFR
|
Cancer
|
|
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling .
|
-
-
- HY-149835
-
|
|
Fluorescent Dye
|
Others
|
|
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .
|
-
-
- HY-D3252
-
|
|
Fluorescent Dye
|
Others
|
|
IR 650 maleimide is a near-infrared fluorescent dye. It should be noted that IR 650 maleimide‘s fluorescence stability is poor, with less than 16% of the fluorescence signal retained after the expansion microscopy experimental procedure .
|
-
-
- HY-D3209
-
|
|
Fluorescent Dye
Quinone Reductase
|
Cancer
|
|
NIR-ASM is a near-infrared fluorescent probe that can cross cell membranes and be activated by NQO1. NIR-ASM can distinguish NQO1-expressing cancer cells from normal cells via fluorescence microscopy and flow cytometry. NIR-ASM generates near-infrared fluorescence with a high signal-to-noise ratio in tumor models with NQO1 activity, enabling the detection of endogenous NQO1 activity in vivo. NIR-ASM is applicable to the research of lung cancer and breast cancer .
|
-
-
- HY-D2998
-
|
|
Fluorescent Dye
|
Others
|
|
ONOO-LysopH is a new Rhodamine-based near-infrared fluorescent probe. ONOO-LysopH is acid-sensitive, exhibiting rapid near-infrared fluorescence enhancement around 686 nm under acidic pH conditions. ONOO-LysopH also displays a rapid NIR turn-on fluorescence around 678 nm for ONOO− at physiological pH. ONOO-LysopH can target lysosomes to track lysosomal pH changes and image endogenous/exogenous ONOO− in live cells. ONOO-LysopH is applicable for cell imaging ONOO− and tracking lysosomal pH changes .
|
-
-
- HY-D3222
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
NIR-PN1 is a blood-brain barrier-permeable near-infrared fluorescent indicator targeting peroxynitrite anion (ONOO −) (Ex/Em = 510 nm/670 nm). NIR-PN1 reacts with ONOO − to trigger a strong near-infrared fluorescence enhancement, enabling the detection of ONOO − flux. NIR-PN1 allows the imaging of ONOO − flux in various Parkinson's disease models. NIR-PN1 is applicable to Parkinson's disease-related research .
|
-
-
- HY-D3181
-
|
|
Fluorescent Dye
Caspase
|
Cancer
|
|
CyGbPF is a granzyme B-specific near-infrared fluorescent probe. CyGbPF can be cleaved by granzyme B to remove the peptide cage group, restoring near-infrared fluorescence. CyGbPF passively accumulates in mouse tumors, and its activated fluorescence correlates with granzyme B expression, CD8 + cytotoxic T lymphocyte populations, and CD4 + helper T lymphocyte populations in tumor tissues. CyGbPF is efficiently cleared by the kidneys, enabling the assessment of immune activation via optical urine analysis. CyGbPF allows real-time non-invasive evaluation of cancer immunotherapeutic efficacy in living animals. CyGbPF can be used in research on cancers such as breast cancer. Excitation wavelength/emission wavelength: approximately 658 nm/approximately 717 nm .
|
-
-
- HY-D3291
-
|
|
Fluorescent Dye
|
Others
|
|
IR 680LT Maleimide is a near-infrared low-band fluorescence dye, composed of the IR 680LT dye core and maleimide groups. IR 680LT Maleimide is used for specifically labeling biologically active molecules containing sulfhydryl groups (Ex/Em = 679 nm/694 nm).
|
-
-
- HY-P992459
-
|
|
ADC Antibody
Transmembrane Glycoprotein
|
Cancer
|
|
SGM-101 Antibody is a chimeric monoclonal antibody targeting carcinoembryonic antigen (CEA). SGM-101 Antibody can serve as a tumor-specific fluorescent imaging probe after being covalently conjugated with the near-infrared fluorescent dye BM104 . SGM-101 Antibody accumulates in CEA-positive tumor tissues via antigen-antibody specific binding, and emits near-infrared fluorescence to enable imaging of tumor lesions. SGM-101 Antibody can be used in research related to gastric cancer, colorectal cancer, pancreatic cancer, non-small cell lung cancer, breast cancer, peritoneal carcinomatosis, and liver metastases .
|
-
-
- HY-D2977
-
|
|
Fluorescent Dye
Autophagy
Fungal
|
Infection
|
|
AF-1 is a azole-based near-infrared fluorescence diagnostic probe with an emission wavelength of 632 nm. AF-1 selectively accumulates in fungal cell membranes at physiological pH. AF-1 targets and induces Autophagy. AF-1 exhibits antifungal activity and sensitivity to autophagy-related pH .
|
-
-
- HY-D3140
-
|
|
Fluorescent Dye
Tyrosinase
|
Cancer
|
|
MB-m-borate is a double-locked near-infrared fluorescence-activated probe (Ex/Em ≈ 647 nm/684 nm). MB-m-borate undergoes cascade activation by hydrogen peroxide and tyrosinase to release the fluorophore methylene blue, thereby generating a fluorescence activation response. MB-m-borate enables precise detection of melanoma in melanoma cells and mouse models. MB-m-borate can be used for melanoma research .
|
-
- HY-D3152
-
|
|
Fluorescent Dye
|
Others
|
|
NRh-Cu is a highly sensitive near-infrared fluorescence turn-on indicator and Cu 2+-selective probe (λex=680 nm, λem=740 nm). When NRh-Cu interacts with Cu 2+, it undergoes a structural transition from a non-fluorescent spirocyclic state to a fluorescent ring-opened state, which drives the enhancement of fluorescence emission. NRh-Cu can be used for Cu 2+ imaging in live cells and in vivo .
|
-
- HY-D2997
-
|
|
Fluorescent Dye
|
Cancer
|
|
1,2-Dimethylpyridinium iodide-Bodipy (Probe 1) is an H2S fluorescent probe. Self-assembled 1,2-Dimethylpyridinium iodide-Bodipy exhibits highly efficient responsiveness to H2S. The assembled form of 1,2-Dimethylpyridinium iodide-Bodipy emits near-infrared fluorescence at 718 nm upon H2S activation .
|
-
- HY-123612
-
|
|
Choline Kinase
Early 2 Factor (E2F)
Fluorescent Dye
|
Neurological Disease
Cancer
|
|
JAS239 is a blood-brain barrier-permeable ChoK inhibitor. JAS239 inhibits phosphocholine synthesis and reduces the expression level of E2F1 protein. JAS239 exhibits near-infrared fluorescence properties. JAS239 exerts anti-tumor activity against glioblastoma. JAS239 can be used in studies related to glioblastoma .
|
-
- HY-D2962
-
|
|
Fluorescent Dye
|
Neurological Disease
|
CAQ is a near-infrared fluorescent probe based on a curcumin scaffold (Ex/Em = 565/635). CAQ exhibits high affinity for Aβ1-42 aggregates (Kd = 78.89 nM) and excellent selectivity toward common biomolecules. CAQ’s emission wavelength shows significant solvent dependence. CAQ, by incorporating intramolecular rotation donors and quinoline functional groups, can be used for the specific detection and imaging of Aβ aggregates in Alzheimer's disease .
|
-
- HY-D3235
-
|
|
Fluorescent Dye
|
Endocrinology
|
|
FDOCl-22 is a HOCl-responsive probe. FDOCl-22 reacts with hypochlorous acid to significantly enhance near-infrared emission and absorption signals, enabling the detection of HOCl levels associated with reagent-induced acute kidney injury. FDOCl-22 can be used in studies related to reagent-induced acute kidney injury .
|
-
-
- HY-D1540
-
|
Cy 5.5 amine; Lumiprobe Cy 5.5 amine
|
Fluorescent Dyes
|
|
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
|
-
- HY-145746
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .
|
-
- HY-D2189
-
|
IR 700DX NHS ester
|
Fluorescent Dyes
|
|
IR 700DX (IR 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye with extremely high photostability and fluorescence intensity. IR 700DX binds to biomolecules. IR 700DX has excellent water solubility, large extinction coefficient, high fluorescence quantum yield, and does not aggregate in high ionic strength buffers. IR 700DX can be used as a highly flexible photosensitizer .
|
-
- HY-D1872
-
|
|
Fluorescent Dyes
|
|
800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .
|
-
- HY-D1744
-
|
|
Fluorescent Dyes
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
|
-
- HY-D2365
-
|
|
Fluorescent Dyes
|
|
QSY 21 NHS is a dark quencher and an efficient energy transfer acceptor for far-red and near-infrared fluorescent probes. QSY 21 NHS operates at a wavelength range of 540-750 nm and is commonly used in FRET applications. QSY 21 NHS does not fluoresce under normal conditions. The NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. QSY 21 NHS can be conjugated with dendritic poly-L-lysine to achieve intramolecular quenching of Cy5 fluorescence .
|
-
- HY-D1555
-
|
Cy7 DBCO
|
Fluorescent Dyes
|
|
Cyanine7 DBCO (Cy7 DBCO) is a near-infrared fluorescent dye and an efficient bio-orthogonal quencher. Cyanine7 DBCO is formed by covalent connection of the near-infrared fluorescent dye Cy7 and the dibenzocyclooctyne (DBCO) functional group. After reacting with N3-Cy5-COOH, the fluorescence of Cy5 decreases by 90% within 90 minutes, and rapid signal attenuation can be observed within 2-5 minutes. Cyanine7 DBCO can be used for the study of deep tissue imaging and receptor-targeted therapeutic strategies .
|
-
- HY-D2864
-
|
|
Fluorescent Dyes
|
|
Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
|
-
- HY-D2062
-
|
|
Fluorescent Dyes
|
|
ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .
|
-
- HY-D1174
-
|
|
Fluorescent Dyes
|
|
Rhodamine 700, a Lambdachrome laser dye, is one of the few rhodamine dyes with near infrared fluorescence. Rhodamine 700 can be used for mitochondrial staining .
|
-
- HY-D2195
-
|
|
Fluorescent Dyes
|
|
AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.
|
-
- HY-D2198
-
|
|
Fluorescent Dyes
|
|
AgAuSe-PEG-NH2 (1120 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1120 nm that can be used in bioimaging .
|
-
- HY-D2971
-
|
|
Fluorescent Dyes
|
|
NCIC-VIS is a lysosome-targeted, viscosity-sensitive two-photon near-infrared fluorescent probe. NCIC-VIS has a rigid structure that can restrict molecular torsion, thereby increasing the fluorescence quantum yield and two-photon absorption cross-section. NCIC-VIS enables real-time imaging of the autophagy process in cells .
|
-
- HY-D2940
-
|
SiR650-BG
|
Fluorescent Dyes
|
SiR-SNAP (SiR650-BG) is a SiR-labeled SNAP tag near-infrared fluorescent probe (Ex/Em: 645 nm/661 nm). SiR-SNAP combines excellent optical properties, good cell membrane permeability, and environmentally sensitive fluorescence characteristics, providing a powerful tool for the dynamic study of proteins in living cells .
|
-
- HY-D1391
-
|
PbS/CdSe QD
|
Fluorescent Dyes
|
|
PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window .
|
-
- HY-D2060
-
|
|
Fluorescent Dyes
|
|
ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
|
-
- HY-D3002
-
|
|
Fluorescent Dyes
|
|
ONOO-/O2- tracker probe is a dual-responsive near-infrared fluorescent probe. ONOO-/O2- tracker probe will only emit a strong fluorescence signal when both peroxynitrite (ONOO⁻) and superoxide anion (O₂•⁻), the two key reactive oxygen/nitrogen species, are present simultaneously. ONOO-/O2- tracker probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
|
-
- HY-D3000
-
|
|
Fluorescent Dyes
|
|
NIR-RED ROS-H2O2 Probe is a near-infrared fluorescent probe used for detecting hydrogen peroxide (H₂O₂) and featuring dual-modal fluorescence/photoacoustic imaging capabilities. NIR-RED ROS-H2O2 Probe successfully detects the upregulated fluorescence signal of H₂O₂ in HepG2 cells and a mouse liver injury model. NIR-RED ROS-H2O2 Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
|
-
- HY-D1065
-
|
|
Fluorescent Dyes
|
|
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
|
-
- HY-D2968
-
|
|
Fluorescent Dyes
|
|
DCM-ONOO is a near-infrared two-photon fluorescence probe specifically designed for real-time monitoring of the dynamic fluctuations of peroxynitrite (ONOO⁻) in epilepsy models. DCM-ONOO exhibits excellent optical properties, with a single photon excitation (Ex) of 520 nm; a single photon emission (Em) of 685 nm; a two-photon excitation of 820 nm; and a Stokes shift of 165 nm. When DCM-ONOO is combined with ONOO⁻, it shifts from 460 nm to 512 nm, and only generates a significant fluorescence response to ONOO⁻. DCM-ONOO has been successfully applied to rat epilepsy models .
|
-
- HY-D2279
-
|
|
Fluorescent Dyes
|
|
NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .
|
-
- HY-150978
-
|
|
Fluorescent Dyes
|
|
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .
|
-
- HY-D2194
-
|
|
Fluorescent Dyes
|
|
AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
|
-
- HY-D3214
-
|
|
Fluorescent Dyes
|
|
NIR-Cu (Ⅱ) is a near-infrared fluorescent Cu 2+ probe. NIR-Cu (Ⅱ) enables fluorescence imaging of Cu 2+ in living mice. NIR-Cu (Ⅱ) reduces self-absorption and exhibits minimal photobleaching, thus supporting in vivo imaging applications .
|
-
- HY-D2970
-
|
|
Fluorescent Dyes
|
|
Golgi-P is a near-infrared Golgi-targeted fluorescent probe specifically used for the detection of Golgi polarity in living cells and living tissues. Golgi-P exhibits a significant polarity-dependent spectral behavior, with its emission wavelength shifting redward with polarity (Ex/Em: 700 nm/780-825 nm). Golgi-P achieves near-infrared fluorescence imaging directly in the brain tissue of depressed mice. Golgi-P combines polarity sensing with Golgi-targeting functionality, providing a new tool for the molecular diagnosis of depression .
|
-
- HY-D3003
-
|
|
Fluorescent Dyes
|
|
M-H2S is an endoplasmic reticulum-targeted ratio-type near-infrared fluorescent probe (Ex/Em : 480 nm/560 nm) specifically designed for the detection of hydrogen sulfide (H2S) in living cells and zebrafish. M-H2S exhibits detection limit for H2S of 39.1 nM, and the fluorescence intensity ratio (F₆₅₀/F₅₆₀) within the range of 0-40 μM shows a linear relationship with the H2S concentration. M-H2S responds best under pH = 7.2 (the normal physiological pH of the endoplasmic reticulum) conditions, making it suitable for the detection of the microenvironment of the endoplasmic reticulum. M-H2S can be used to study the role of H2S in endoplasmic reticulum function, stress response, and related diseases .
|
-
- HY-D3234
-
|
|
Fluorescent Dyes
|
|
Cy-AP is a hypoxia-sensitive near-infrared Fluorescent probe (emission wavelength: 725 nm). Cy-AP exhibits no fluorescence under normoxic microenvironments, while under hypoxic microenvironments, its azo group is reduced, releasing strong near-infrared fluorescence with an emission at 725 nm. Cy-AP enables visualization of intracellular hypoxic status through multiple imaging modalities .
|
-
- HY-149835
-
|
|
Fluorescent Dyes
|
|
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .
|
-
- HY-D3252
-
|
|
Fluorescent Dyes
|
|
IR 650 maleimide is a near-infrared fluorescent dye. It should be noted that IR 650 maleimide‘s fluorescence stability is poor, with less than 16% of the fluorescence signal retained after the expansion microscopy experimental procedure .
|
-
- HY-D3209
-
|
|
Fluorescent Dyes
|
|
NIR-ASM is a near-infrared fluorescent probe that can cross cell membranes and be activated by NQO1. NIR-ASM can distinguish NQO1-expressing cancer cells from normal cells via fluorescence microscopy and flow cytometry. NIR-ASM generates near-infrared fluorescence with a high signal-to-noise ratio in tumor models with NQO1 activity, enabling the detection of endogenous NQO1 activity in vivo. NIR-ASM is applicable to the research of lung cancer and breast cancer .
|
-
- HY-D2998
-
|
|
Fluorescent Dyes
|
|
ONOO-LysopH is a new Rhodamine-based near-infrared fluorescent probe. ONOO-LysopH is acid-sensitive, exhibiting rapid near-infrared fluorescence enhancement around 686 nm under acidic pH conditions. ONOO-LysopH also displays a rapid NIR turn-on fluorescence around 678 nm for ONOO− at physiological pH. ONOO-LysopH can target lysosomes to track lysosomal pH changes and image endogenous/exogenous ONOO− in live cells. ONOO-LysopH is applicable for cell imaging ONOO− and tracking lysosomal pH changes .
|
-
- HY-D3222
-
|
|
Fluorescent Dyes
|
|
NIR-PN1 is a blood-brain barrier-permeable near-infrared fluorescent indicator targeting peroxynitrite anion (ONOO −) (Ex/Em = 510 nm/670 nm). NIR-PN1 reacts with ONOO − to trigger a strong near-infrared fluorescence enhancement, enabling the detection of ONOO − flux. NIR-PN1 allows the imaging of ONOO − flux in various Parkinson's disease models. NIR-PN1 is applicable to Parkinson's disease-related research .
|
-
- HY-D3181
-
|
|
Fluorescent Dyes
|
|
CyGbPF is a granzyme B-specific near-infrared fluorescent probe. CyGbPF can be cleaved by granzyme B to remove the peptide cage group, restoring near-infrared fluorescence. CyGbPF passively accumulates in mouse tumors, and its activated fluorescence correlates with granzyme B expression, CD8 + cytotoxic T lymphocyte populations, and CD4 + helper T lymphocyte populations in tumor tissues. CyGbPF is efficiently cleared by the kidneys, enabling the assessment of immune activation via optical urine analysis. CyGbPF allows real-time non-invasive evaluation of cancer immunotherapeutic efficacy in living animals. CyGbPF can be used in research on cancers such as breast cancer. Excitation wavelength/emission wavelength: approximately 658 nm/approximately 717 nm .
|
-
- HY-D3291
-
|
|
Fluorescent Dyes
|
|
IR 680LT Maleimide is a near-infrared low-band fluorescence dye, composed of the IR 680LT dye core and maleimide groups. IR 680LT Maleimide is used for specifically labeling biologically active molecules containing sulfhydryl groups (Ex/Em = 679 nm/694 nm).
|
-
- HY-D2977
-
|
|
Fluorescent Dyes
|
|
AF-1 is a azole-based near-infrared fluorescence diagnostic probe with an emission wavelength of 632 nm. AF-1 selectively accumulates in fungal cell membranes at physiological pH. AF-1 targets and induces Autophagy. AF-1 exhibits antifungal activity and sensitivity to autophagy-related pH .
|
-
- HY-D3140
-
|
|
Fluorescent Dyes
|
|
MB-m-borate is a double-locked near-infrared fluorescence-activated probe (Ex/Em ≈ 647 nm/684 nm). MB-m-borate undergoes cascade activation by hydrogen peroxide and tyrosinase to release the fluorophore methylene blue, thereby generating a fluorescence activation response. MB-m-borate enables precise detection of melanoma in melanoma cells and mouse models. MB-m-borate can be used for melanoma research .
|
-
- HY-D3152
-
|
|
Fluorescent Dyes
|
|
NRh-Cu is a highly sensitive near-infrared fluorescence turn-on indicator and Cu 2+-selective probe (λex=680 nm, λem=740 nm). When NRh-Cu interacts with Cu 2+, it undergoes a structural transition from a non-fluorescent spirocyclic state to a fluorescent ring-opened state, which drives the enhancement of fluorescence emission. NRh-Cu can be used for Cu 2+ imaging in live cells and in vivo .
|
-
- HY-D2997
-
|
|
Fluorescent Dyes
|
|
1,2-Dimethylpyridinium iodide-Bodipy (Probe 1) is an H2S fluorescent probe. Self-assembled 1,2-Dimethylpyridinium iodide-Bodipy exhibits highly efficient responsiveness to H2S. The assembled form of 1,2-Dimethylpyridinium iodide-Bodipy emits near-infrared fluorescence at 718 nm upon H2S activation .
|
-
- HY-D2962
-
|
|
Fluorescent Dyes
|
CAQ is a near-infrared fluorescent probe based on a curcumin scaffold (Ex/Em = 565/635). CAQ exhibits high affinity for Aβ1-42 aggregates (Kd = 78.89 nM) and excellent selectivity toward common biomolecules. CAQ’s emission wavelength shows significant solvent dependence. CAQ, by incorporating intramolecular rotation donors and quinoline functional groups, can be used for the specific detection and imaging of Aβ aggregates in Alzheimer's disease .
|
-
- HY-D3235
-
|
|
Fluorescent Dyes
|
|
FDOCl-22 is a HOCl-responsive probe. FDOCl-22 reacts with hypochlorous acid to significantly enhance near-infrared emission and absorption signals, enabling the detection of HOCl levels associated with reagent-induced acute kidney injury. FDOCl-22 can be used in studies related to reagent-induced acute kidney injury .
|
| Cat. No. |
상품명 |
Target |
Research Area |
-
- HY-P6083
-
|
|
Biochemical Assay Reagents
|
Others
Cancer
|
|
RTSPSSR is synthesized peptide, which binds specifically to claudin-1 and visulizes the CRC tumor in mice, through near-infrared fluorescence imaging .
|
-
- HY-P5520
-
|
|
Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
|
-
- HY-P10788
-
|
|
Complement System
|
Cancer
|
|
CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer.
|
-
- HY-P10052
-
|
|
VEGFR
|
Cancer
|
|
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling .
|
-
- HY-P3196
-
|
|
Peptides
|
Cancer
|
|
Tozuleristide is a tumor-targeting agent covalently conjugated to a derivative of the near-infrared fluorescent dye indocyanine green (ICG). Tozuleristide has the ability to penetrate the blood-brain barrier. Tozuleristide can be used in research related to fluorescence-guided surgery (FGS) .
|
-
- HY-KD1110
-
|
|
|
The Near-Infrared Fluorescence Rapid Labelling Kit (CY7.5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 788/814 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of CY7.5. The entire procedure can be completed within two hours.
|
| Cat. No. |
상품명 |
Target |
Research Area |
Image |
-
- HY-P991650
-
|
|
PSMA
|
Cancer
|
|
MDX1201 is a humanized monoclonal antibody targeting PSMA1/7. MDX1201 conjugated with a fluorescent dye AlexaTM488 can be used as a probe for near-infrared fluorescence imaging (NIRF) imaging of prostate cancer .
|
-
(5)
-
- HY-P992459
-
|
|
ADC Antibody
Transmembrane Glycoprotein
|
Cancer
|
|
SGM-101 Antibody is a chimeric monoclonal antibody targeting carcinoembryonic antigen (CEA). SGM-101 Antibody can serve as a tumor-specific fluorescent imaging probe after being covalently conjugated with the near-infrared fluorescent dye BM104 . SGM-101 Antibody accumulates in CEA-positive tumor tissues via antigen-antibody specific binding, and emits near-infrared fluorescence to enable imaging of tumor lesions. SGM-101 Antibody can be used in research related to gastric cancer, colorectal cancer, pancreatic cancer, non-small cell lung cancer, breast cancer, peritoneal carcinomatosis, and liver metastases .
|
-
(5)
| Cat. No. |
상품명 |
Category |
Target |
Chemical Structure |
-
- HY-N16309
-
|
|
Lipid
|
Fluorescent Dye
|
|
Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.
|
-
-
- HY-165424
-
-
| Cat. No. |
상품명 |
|
Classification |
-
- HY-145746
-
|
|
|
Azide
Labeling and Fluorescence Imaging
|
|
Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .
|
-
- HY-D1555
-
|
Cy7 DBCO
|
|
DBCO
|
|
Cyanine7 DBCO (Cy7 DBCO) is a near-infrared fluorescent dye and an efficient bio-orthogonal quencher. Cyanine7 DBCO is formed by covalent connection of the near-infrared fluorescent dye Cy7 and the dibenzocyclooctyne (DBCO) functional group. After reacting with N3-Cy5-COOH, the fluorescence of Cy5 decreases by 90% within 90 minutes, and rapid signal attenuation can be observed within 2-5 minutes. Cyanine7 DBCO can be used for the study of deep tissue imaging and receptor-targeted therapeutic strategies .
|
Your information is safe with us. * Required Fields.
Inquiry Information
- 상품명:
- Cat. No.:
- 수량:
- MCE Japan Authorized Agent: