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Results for "

neutropenia

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Antibiotic (4) Bacterial (6) c-Fms (1) CD20 (1) Drug Derivative (1) Endogenous Metabolite (1) Histone Methyltransferase (1) Isotope-Labeled Compounds (1) Liposome (1) NF-κB (1) Penicillin-binding protein (PBP) (4) Reference Standards (1) Topoisomerase (1)
By Research Areas:	Cancer (10) Cardiovascular Disease (4) Endocrinology (1) Infection (5) Inflammation/Immunology (6)
Oligonucleotides:	Liposome (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13678

Meropenem 30+ Cited Publications SM 7338	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection Cancer
Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-13678A

Meropenem trihydrate Maximum Cited Publications 32 Publications Verification SM 7338 trihydrate	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection Cancer
Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-13678AR

Meropenem trihydrate (Standard) SM 7338 trihydrate (Standard)	Penicillin-binding protein (PBP) Reference Standards Bacterial Antibiotic	Infection Cancer
Meropenem (trihydrate) (Standard) is the analytical standard of Meropenem (trihydrate). This product is intended for research and analytical applications. Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-130581

Lipid X	Bacterial	Cardiovascular Disease Inflammation/Immunology
Lipid X is a 2,3-diacylglucosamine-1-phosphate that serves as the monosaccharide precursor of lipid A, possessing both LPS antagonist and weak agonist activities. Lipid X exerts protective effects by inhibiting tumor necrosis factor production, monocyte procoagulant activity, and neutrophil priming. Lipid X may induce transient pulmonary hypertension, neutropenia, and mild pyrogenic effects in laboratory animals. Lipid X has low toxicity and no in vitro antibacterial activity, but it significantly reduces mortality following Gram-negative bacterial infection and endotoxin exposure. Lipid X tends to accumulate in liver tissue, binds to circulating cellular components, and can be converted to lipid Y through transesterification. Lipid X can be used in research on Gram-negative bacterial sepsis, endotoxemia, and associated pulmonary hypertension .

HY-P99952

Ripertamab SCT400	CD20	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Ripertamab (SCT400) is a recombinant human-mouse chimeric anti-CD20 IgG1κ monoclonal antibody. As an immunomodulator, ripertamab reduces the levels of pathogenic autoantibodies, alleviates immune complex deposition, and blocks the antigen-presenting function of cells. Ripertamab depletes CD20-positive cells. Ripertamab can induce infusion-related reactions, pulmonary toxicity, neutropenia and thrombocytopenia. Ripertamab is applicable to research related to non-Hodgkin's lymphoma, primary membranous nephropathy and idiopathic membranous nephropathy .

HY-118028

Leyk	Drug Derivative	Cardiovascular Disease Inflammation/Immunology
Leyk is an orally active Cysteine derivative. Leyk stimulates bone marrow hematopoiesis. Leyk exerts a significant protective effect against cyclophosphamide-induced leukopenia. Leyk can be used in studies related to thrombocytopenia and leukopenia .

HY-N6692S

Diacetoxyscirpenol-13C19	Endogenous Metabolite Isotope-Labeled Compounds	Inflammation/Immunology
Diacetoxyscirpenol- ¹³C₁₉ is ¹³C labeled Diacetoxyscirpenol (HY-N6692). Diacetoxyscirpenol (DAS) is a trichothecene mycotoxin, a secondary metabolite product of fungi. Diacetoxyscirpenol (DAS) consumption induces haematological disorders (neutropenia, aplastic anemia) in human and animals .

HY-P99913

Eflapegrastim	c-Fms	Inflammation/Immunology Cancer
Eflapegrastim is a composite protein consisting of a genetically modified granulocyte-colony stimulating factor (GCSF) molecule linked via a chemical bond to an IgG4 Fc fragment (LAPS-carrier). Eflapegrastim targets to G-CSF receptor (c-Fms). Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia .

HY-178028

PRMT5-IN-53	Histone Methyltransferase	Cancer
PRMT5-IN-53 is a gut-restricted and orally active PRMT5 inhibitor with pIC₅₀s of ≥ 9.7 against hPRMT5 and mPRMT5. PRMT5-IN-53 binds to the PRMT5:MEP50 complex with a K_D of 11.3 pM. PRMT5-IN-53 effectively inhibits PRMT5 locally in the intestines of mice, significantly reducing the number and area of polyps, while avoiding systemic hematological toxicity (such as anemia, neutropenia). PRMT5-IN-53 can be used for the study of colorectal cancer especially for familial adenomatous polyposis (FAP) .

HY-111984A

Quinazosin dihydrochloride	Adrenergic Receptor	Cardiovascular Disease
Quinazosin dihydrochloride is an antihypertensive α1-adrenergic receptor antagonist whose activity is associated with inhibition of granulopoiesis, resulting in neutropenia and leukopenia. Quinazosin dihydrochloride exhibits dose-related myelosuppression that is correlated with the duration of suppression .

HY-151164

LasR-IN-2	Bacterial	Infection
LasR-IN-2 is a LasR inhibitor that forms H-bonding with TRY-56 residue. LasR-IN-2 can be used in the research of bacterial infection, neutropenia, severe burns and chronic lung disease in cystic fibrosis (CF) .

HY-W740053

Meropenem sodium	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection Cancer
Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-100307

SB 247464	Others	Others
SB 247464 is an orally active nonpeptidyl ligand. SB 247464 can selectively activate the murine granulocyte colony-stimulating factor (G-CSF) signaling pathway and mimic the biological functions of G-CSF. SB 247464 can be used for the study of neutropenia and other diseases .

HY-185371

Irinotecan liposome Irinotecan hydrochlorid liposomee; Liposomal irinotecan	Liposome Topoisomerase	Cancer
Irinotecan liposome is a liposome-encapsulated form of Irinotecan hydrochlorid (HY-16562A) (a topoisomerase I inhibitor). Compared with Irinotecan, Irinotecan liposome enhances antitumor activity, reduces drug release rate, and avoids neutropenia.

HY-P992178

ALLO-647	NF-κB	Cancer
ALLO-647 is a human monoclonal antibody targeting CD52. ALLO-647 transiently and selectively depletes host lymphocytes to promote the proliferation of allogeneic CAR T-cell following infusion. ALLO-647 can be used for the research of B-cell lymphoma and follicular lymphoma .

Meropenem sodium	Biochemical Assay Reagents
Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99952

Ripertamab SCT400	CD20	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Ripertamab (SCT400) is a recombinant human-mouse chimeric anti-CD20 IgG1κ monoclonal antibody. As an immunomodulator, ripertamab reduces the levels of pathogenic autoantibodies, alleviates immune complex deposition, and blocks the antigen-presenting function of cells. Ripertamab depletes CD20-positive cells. Ripertamab can induce infusion-related reactions, pulmonary toxicity, neutropenia and thrombocytopenia. Ripertamab is applicable to research related to non-Hodgkin's lymphoma, primary membranous nephropathy and idiopathic membranous nephropathy .

HY-P99913

Eflapegrastim	c-Fms	Inflammation/Immunology Cancer
Eflapegrastim is a composite protein consisting of a genetically modified granulocyte-colony stimulating factor (GCSF) molecule linked via a chemical bond to an IgG4 Fc fragment (LAPS-carrier). Eflapegrastim targets to G-CSF receptor (c-Fms). Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia .

HY-P990963

Albipagrastim alfa	Inhibitory Antibodies	Inflammation/Immunology Cancer
Albipagrastim alfa is a long-acting granulocyte colony-stimulating factor (G-CSF), which is formed by the fusion of highly active recombinant G-CSF and human serum albumin (HSA). Albipagrastim alfa can significantly inhibit the clearance pathway mediated by the G-CSF receptor. Albipagrastim alfa can be used in tumor-related research .

HY-P992178

ALLO-647	NF-κB	Cancer
ALLO-647 is a human monoclonal antibody targeting CD52. ALLO-647 transiently and selectively depletes host lymphocytes to promote the proliferation of allogeneic CAR T-cell following infusion. ALLO-647 can be used for the research of B-cell lymphoma and follicular lymphoma .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13678

Meropenem 30+ Cited Publications SM 7338	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Beta-lactam Antibiotics Source Classification	Penicillin-binding protein (PBP) Bacterial Antibiotic
Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

Cat. No.	Product Name	Chemical Structure

HY-N6692S

Diacetoxyscirpenol-13C19
Diacetoxyscirpenol- ¹³C₁₉ is ¹³C labeled Diacetoxyscirpenol (HY-N6692). Diacetoxyscirpenol (DAS) is a trichothecene mycotoxin, a secondary metabolite product of fungi. Diacetoxyscirpenol (DAS) consumption induces haematological disorders (neutropenia, aplastic anemia) in human and animals .

Cat. No.	Product Name		Classification

HY-185371

Irinotecan liposome Irinotecan hydrochlorid liposomee; Liposomal irinotecan		Liposome
Irinotecan liposome is a liposome-encapsulated form of Irinotecan hydrochlorid (HY-16562A) (a topoisomerase I inhibitor). Compared with Irinotecan, Irinotecan liposome enhances antitumor activity, reduces drug release rate, and avoids neutropenia.

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neutropenia

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
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