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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
obesity-related disorders
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "obesity-related disorders" in MCE Product Catalog:
Cat. No.: HY-173527
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PSSI-51 is an orally active, peripherally selective inhibitor of succinyl-CoA:3-ketoacid-CoA transferase (SCOT). PSSI-51 inhibits SCOT activity in peripheral tissues (such as muscle and kidney) but does not affect SCOT activity in brain tissue. PSSI-51 reduces ketone body oxidation by inhibiting SCOT, thereby improving obesity-related hyperglycemia. PSSI-51 can be used in the study of type 2 diabetes (T2D) and has the potential to improve obesity-related metabolic disorders .
Cat. No.: HY-14753
CAS No.: 861151-12-4
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Rosonabant is a selective antagonist for cannabinoid receptor (CB1 receptor), which reduces body weight and improves improves the risk of obesity-related cardiovascular metabolic diseases. Rosonabant exhibits adverse side effect, such as nausea and mental disorder .
Cat. No.: HY-19848
CAS No.: 839673-52-8
Synonyms: LBM-642
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Cevoglitazar (LBM-642) is an orally active and highly potent PPARα and PPARγ dual agonist. Cevoglitazar can reduce food intake, body weight, and fasting plasma insulin in obese mice and cynomolgus monkeys. Cevoglitazar has the potential for diabetes and obesity-related disorders research .
Cat. No.: HY-P1257
CAS No.: 117442-28-1
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Xenin-8 is the C-terminal octapeptide fragment of xenin, which belongs to the xenopsin family of peptides. Xenin-8 stimulates basal insulin secretion, dose-dependently enhances glucose (EC50 = 0.16 nM) and arginine-induced insulin release, and enhances arginine- and Carbamoylcholine chloride (HY-B1208)-induced glucagon secretion. Xenin-8 antagonizes the inhibition of glucagon release by elevated glucose. Xenin-8 can be used in research on type 2 diabetes and obesity-related glucose metabolic disorders .
Cat. No.: HY-W769935
CAS No.: 2161370-68-7
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5-POHSA is a CD36 and Src kinase modulator acting on taste bud cells, and belongs to the fatty acid esters of hydroxy fatty acids (FAHFA) family. 5-POHSA binds to lingual CD36 to initiate intracellular signaling pathways, activate downstream Src kinase, and rapidly elevate intracellular calcium levels. 5-POHSA interacts with the tongue-brain axis by binding to CD36, so as to ameliorate taste disorders and obesity-related adverse reactions. 5-POHSA is applicable to the research of obesity .
Cat. No.: HY-P1257A
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Xenin-8 TFA is the C-terminal octapeptide fragment of xenin, which belongs to the xenopsin family of peptides. Xenin-8 TFA stimulates basal insulin secretion, dose-dependently enhances glucose (EC50 = 0.16 nM) and arginine-induced insulin release, and enhances arginine- and Carbamoylcholine chloride (HY-B1208)-induced glucagon secretion. Xenin-8 TFA antagonizes the inhibition of glucagon release by elevated glucose. Xenin-8 TFA can be used in research on type 2 diabetes and obesity-related glucose metabolic disorders .
Cat. No.: HY-N13198
CAS No.: 356517-93-6
Category:
Rhodiola sacra (Prain ex Raym.-Hamet) S. H. Fu Phenols Polyphenols Crassulaceae Extract Plants
Target:
Cat. No.: HY-P1257B
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Xenin-8 acetate is the C-terminal octapeptide fragment of xenin, which belongs to the xenopsin family of peptides. Xenin-8 acetate stimulates basal insulin secretion, dose-dependently enhances glucose (EC50 = 0.16 nM) and arginine-induced insulin release, and enhances arginine- and Carbamoylcholine chloride (HY-B1208)-induced glucagon secretion. Xenin-8 acetate antagonizes the inhibition of glucagon release by elevated glucose. Xenin-8 acetate can be used in research on type 2 diabetes and obesity-related glucose metabolic disorders .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
