1. Search Result
Search Result
Results for "

progestin

" in MedChemExpress (MCE) Product Catalog:

44

Inhibitors & Agonists

4

Natural
Products

2

Recombinant Proteins

15

Isotope-Labeled Compounds

2

Antibodies

10

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0554
    Norethindrone
    2 Publications Verification

    Norethisterone

    Progesterone Receptor Bacterial Endocrinology Cancer
    Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.
    Norethindrone
  • HY-B0111
    Drospirenone
    1 Publications Verification

    Dihydrospirorenone

    Progesterone Receptor Androgen Receptor Endocrinology Cancer
    Drospirenone (Dihydrospirorenone) is an orally active fourth-generation progestin that interacts with the progesterone receptor (PR) and androgen receptor (AR). Drospirenone significantly decreases both plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator (tPA) via the AR. Drospirenone can produce DNA damage in bone marrow cells of female mice. .
    Drospirenone
  • HY-119384
    Promegestone
    1 Publications Verification

    R-5020; Surgestone

    Progesterone Receptor Endocrinology Cancer
    Promegestone (R-5020), a progestin, is a potent progesterone receptor (PR) agonist. Promegestone has the potential for endocrine regulation and cancer research .
    Promegestone
  • HY-125209

    DNA/RNA Synthesis Cancer
    TH5427 is a promising, targeted inhibitor that can be used to further study NUDT5 activity and ADP-ribose metabolism. TH5427, blocks progestin-dependent, PAR-derived nuclear ATP synthesis and subsequent chromatin remodeling, gene regulation and proliferation in breast cancer cells. NUDT5 is recently identified as a rheostat of hormone-dependent gene regulation and proliferation in breast cancer cells .
    TH5427
  • HY-W013172

    Progesterone Receptor Endocrinology
    Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive . Norgestimate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate
  • HY-B0390

    Environmental Pollutants Estrogen Receptor/ERR Endocrinology Cancer
    Mestranol is an inactive proagent and becomes biologically active on conversion to ethinyl estradiol (EE). Mestranol acts as an estrogen receptor agonist. Mestranol combines with a progestin in vivo and can be used for the research of menopausal hormone or menstrual disorders. Mestranol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Mestranol
  • HY-B0652

    3-Oxodesogestrel; 3-keto-Desogestrel

    Drug Metabolite Estrogen Receptor/ERR Progesterone Receptor Endogenous Metabolite FKBP Endocrinology
    Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs . Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs) .
    Etonogestrel
  • HY-B0554S

    Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Norethindrone-d6 is the deuterium labeled Norethindrone. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea. Norethindrone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norethindrone-d6
  • HY-128378

    Endogenous Metabolite Endocrinology
    16-Dehydroprogesterone is a steroidal progestin.
    16-​Dehydroprogesterone
  • HY-B0110

    SHB 331; WL 70

    Progesterone Receptor Endocrinology
    Gestodene(SHB 331;WL 70) is a progestin-based contraceptive. Gestodene is a click chemistry reagent. It contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an azide group .
    Gestodene
  • HY-111302

    Progesterone Receptor Endocrinology
    Norgestrienone is a progestin receptor agonist. Norgestrienone is commonly used as a progesterone compound in birth control pills and can be combined with ethinylestradiol. Norgestrienone is a click chemical. It contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Azide groups. Norgestrienone can be used in the study of hereditary angioneurotic edema .
    Norgestrienone
  • HY-B0111S

    Dihydrospirorenone-d4

    Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Drospirenone-d4 is the deuterium labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone .
    Drospirenone-d4
  • HY-164032

    7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate

    GnRH Receptor Endocrinology
    Dimethandrolone undecanoate (7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate) exhibits withrogens and progesterone activity. Dimethandrolone undecanoate inhibits production of gonadotropins, suppresses testosterone production, and thus inhibits sperm production. Dimethandrolone undecanoate is potent for development of male hormone contraceptives .
    Dimethandrolone undecanoate
  • HY-125209A

    Apoptosis PARP DNA/RNA Synthesis Cancer
    TH5427 hydrochloride is a NUDT5 inhibitor with a human target IC50 of 29 nM, ~690-fold selectivity over MTH1 in vitro, and selective functional inhibition over other NUDIX hydrolases including NUDT9 .TH5427 hydrochloride binds to the active site of NUDT5, blocking enzymatic activity related to ADP-ribose metabolism and PAR-derived ATP synthesis .TH5427 hydrochloride blocks progestin-dependent nuclear ATP synthesis, impairs progestin-induced chromatin remodeling, inhibits histone H1 displacement, disrupts progestin-dependent gene regulation, and abrogates progestin-dependent proliferation in breast cancer cells .TH5427 hydrochloride functions as a versatile probe to study nuclear ATP dynamics and ADP-ribose-related metabolism in cells .TH5427 hydrochloride engages NUDT5 at physiological temperatures, as demonstrated by Drug Affinity Responsive Target Stability (DARTS) assay .TH5427 hydrochloride stabilizes NUDT5 against thermal denaturation in cell lysates and intact cells, as shown by cellular thermal shift assay (CETSA) .TH5427 hydrochloride functionally inhibits NUDT5 activity, leading to downstream effects on oxidative DNA damage and DNA replication in triple-negative breast cancer (TNBC) cells .TH5427 hydrochloride suppresses proliferation of TNBC cells without inducing cell death or apoptosis, slows DNA replication in TNBC cells, promotes accumulation of oxidative DNA lesions, and triggers DNA damage response in TNBC cells .TH5427 hydrochloride suppresses growth of TNBC cells in vitro, inhibits growth of TNBC xenograft tumors in nude mice in vivo, and shows greater potency against TNBC cell lines compared to ER-positive and normal-like breast cell lines .TH5427 hydrochloride can be used for the research of breast cancer and triple-negative breast cancer .
    TH5427 hydrochloride
  • HY-106827

    RU 27987

    Progesterone Receptor Androgen Receptor Phosphatase Endocrinology
    Trimegestone (RU 27987) is an orally active 19-norpregnane progestin. Trimegestone binds to progesterone receptor (PR) with an IC50 value of 3.3 nM (rat PR). Trimegestone increases alkaline phosphatase activity (EC50=0.1 nM) but not luciferase activity. Trimegestone also shows a weak antiandrogenic activity (weak androgen receptor affinity). Trimegestone can be used in studies of contraception or menopausal syndromes .
    Trimegestone
  • HY-B0652R

    3-Oxodesogestrel (Standard); 3-keto-Desogestrel (Standard)

    Drug Metabolite Reference Standards Estrogen Receptor/ERR Progesterone Receptor Endogenous Metabolite FKBP Endocrinology
    Etonogestrel (Standard) is the analytical standard of Etonogestrel. This product is intended for research and analytical applications. Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs . Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs) .
    Etonogestrel (Standard)
  • HY-U00091

    Gestonorone caproate

    Progesterone Receptor Cancer
    Gestonorone Capronate is a progestin for the treatment of benign prostatic hypertrophy and endometrial cancer.
    Gestonorone Capronate
  • HY-113537

    Lutionex

    Glucocorticoid Receptor Endocrinology
    Demegestone is an agonist of theprogesterone receptor .
    Demegestone
  • HY-B0648S

    17α-Hydroxy-6α-methylprogesterone-d3; U8840-d3

    Progesterone Receptor Endocrinology
    Medroxyprogesterone-d3 is the deuterium labeled Medroxyprogesterone. Medroxyprogesterone is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.
    Medroxyprogesterone-d3
  • HY-105634

    Progesterone Receptor Endocrinology Cancer
    Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity.
    Nomegestrol
  • HY-B0554R
    Norethindrone (Standard)
    2 Publications Verification

    Norethisterone (Standard)

    Reference Standards Progesterone Receptor Bacterial Endocrinology Cancer
    Norethindrone (Standard) is the analytical standard of Norethindrone. This product is intended for research and analytical applications. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.
    Norethindrone (Standard)
  • HY-B0554S2

    Norethisterone-d8

    Isotope-Labeled Compounds Endocrinology Cancer
    Norethindrone-d8 (Norethisterone-d8) is deuterium labeled Norethindrone. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.
    Norethindrone-d8
  • HY-W746582

    Norethisterone-d7

    Isotope-Labeled Compounds Bacterial Progesterone Receptor Endocrinology
    Norethindrone-d7 (Norethisterone-d7) is the deuterium labeled Norethindrone (HY-B0554). Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.
    Norethindrone-d7
  • HY-B0652S1

    3-Oxodesogestrel-d6; 3-keto-Desogestrel-d6

    Isotope-Labeled Compounds Estrogen Receptor/ERR Progesterone Receptor Endogenous Metabolite FKBP Endocrinology
    Etonogestrel-d6 is deuterium labeled Etonogestrel. Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs . Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs) .
    Etonogestrel-d6
  • HY-G0018S

    17-Deacetyl norgestimate-d6; 17-Deacylnorgestimate-d6

    Isotope-Labeled Compounds Drug Metabolite Others
    Norgestimate metabolite norelgestromin-d6 is the deuterium labeled Norgestimate metabolite norelgestromin. Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen. Norgestimate metabolite norelgestromin-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate metabolite norelgestromin-d6
  • HY-105820

    Progesterone Receptor Endocrinology
    Algestone is a progestin that exhibits hormonal contraceptive effects .
    Algestone
  • HY-137944

    Apoptosis Endocrinology
    5α-Dihydro levonorgestrel is a metabolite of the synthetic progestin Levonorgestrel (HY-B0257) .
    5α-Dihydro levonorgestrel
  • HY-W747648

    Endogenous Metabolite Others
    (+)-Norgestrel is a progestin used in birth control pills that has reproductive hormone-regulating activity. (+)-Norgestrel also plays an important role in menopausal hormone suppression .
    (+)-Norgestrel
  • HY-W747043

    Isotope-Labeled Compounds Drug Metabolite Inflammation/Immunology
    Megestrol-d3 is the deuterium labeled Megestrol (HY-B1834). Megestrol is a synthetic progestin and used for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis .
    Megestrol-d3
  • HY-W013172R

    Reference Standards Progesterone Receptor Endocrinology
    Norgestimate (Standard) is the analytical standard of Norgestimate. This product is intended for research and analytical applications. Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive .
    Norgestimate (Standard)
  • HY-W750386

    17α-Hydroxyprogesterone hexanoate-d11; 17α-Hydroxyprogesterone caproate-d11

    Isotope-Labeled Compounds Progesterone Receptor Others
    Hydroxyprogesterone Caproate-d11 (17α-Hydroxyprogesterone hexanoate-d11; 17α-Hydroxyprogesterone caproate-d11) is the deuterium labeled Hydroxyprogesterone caproate (HY-B0742). Hydroxyprogesterone caproate is a synthetic progestin, a steroid.
    Hydroxyprogesterone Caproate-d11
  • HY-B0554S1

    Norethisterone-13C2

    Isotope-Labeled Compounds Progesterone Receptor Bacterial Endocrinology
    Norethindrone- 13C2 (Norethisterone- 13C2) is the 13C labeled Norethindrone (HY-B0554) . Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea .
    Norethindrone-13C2
  • HY-W753897

    Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Gestodene-d7 is the deuterium labeled Gestodene (HY-B0110). Gestodene is a progestin-based contraceptive. Gestodene is a click chemistry reagent. It contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an azide group .
    Gestodene-d7
  • HY-W703425

    delta-5(6)-Norethindrone

    Progesterone Receptor Endocrinology
    17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one (delta-5(6)-Norethindrone), an impurity of Norethindrone, is an anabolic agent. Norethindrone is a progestin athat can be used for endometriosis research .
    17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one
  • HY-135593

    Others Endocrinology
    LY88074 analog 1 is a benzothiophene compound with nitrogen-containing non-basic side chains, Compound 26, extracted from patent EP0747380A1. LY88074 analog 1 is an agent for alleviating the symptoms of post-menopausal symptoms, such as osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. LY88074 analog 1 can be used alone or in combination with estrogen or progestin .
    LY88074 analog 1
  • HY-139244S

    Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Norgestimate-d6 is the deuterium labeled Norgestimate. Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive . Norgestimate-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate-d6
  • HY-B0390R

    Reference Standards Estrogen Receptor/ERR Endocrinology Cancer
    Mestranol (Standard) is the analytical standard of Mestranol. This product is intended for research and analytical applications. Mestranol is an inactive proagent and becomes biologically active on conversion to ethinyl estradiol (EE). Mestranol acts as an estrogen receptor agonist. Mestranol combines with a progestin in vivo and can be used for the research of menopausal hormone or menstrual disorders. Mestranol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Mestranol (Standard)
  • HY-B0390S

    Isotope-Labeled Compounds Estrogen Receptor/ERR Cancer
    Mestranol-d2 is the deuterium labeled Mestranol. Mestranol is an inactive proagent and becomes biologically active on conversion to ethinyl estradiol (EE). Mestranol acts as an estrogen receptor agonist. Mestranol combines with a progestin in vivo and can be used for the research of menopausal hormone or menstrual disorders . Mestranol-d2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Mestranol-d2
  • HY-B0390S1

    Isotope-Labeled Compounds Estrogen Receptor/ERR Cancer
    Mestranol-d4 is the deuterium labeled Mestranol. Mestranol is an inactive proagent and becomes biologically active on conversion to ethinyl estradiol (EE). Mestranol acts as an estrogen receptor agonist. Mestranol combines with a progestin in vivo and can be used for the research of menopausal hormone or menstrual disorders . Mestranol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Mestranol-d4
  • HY-106827S1

    RU 27987-13C,d3

    Androgen Receptor Phosphatase Progesterone Receptor Isotope-Labeled Compounds Endocrinology
    Trimegestone- 13C,d3 is 13C and deuterated labeled Trimegestone (HY-106827). Trimegestone (RU 27987) is an orally active 19-norpregnane progestin. Trimegestone binds to progesterone receptor (PR) with an IC50 value of 3.3 nM (rat PR). Trimegestone increases alkaline phosphatase activity (EC50=0.1 nM) but not luciferase activity. Trimegestone also shows a weak antiandrogenic activity (weak androgen receptor affinity). Trimegestone can be used in studies of contraception or menopausal syndromes .
    Trimegestone-13C,d3
  • HY-N2349

    Progesterone Receptor Cancer
    Melengestrol is a steroidal progestin of the 17α-hydroxyprogesterone group and an antineoplastic agent.
    Melengesterol
  • HY-W746761

    ZK-115194

    Estrogen Receptor/ERR Endocrinology
    Cyclodiol is an estrogen. Cyclodiol is used for fertility control in females and also as oral contraceptives in combination with a variety of progestins .
    Cyclodiol
  • HY-128378R

    Endogenous Metabolite Reference Standards Endocrinology
    16-​Dehydroprogesterone (Standard) is the analytical standard of 16-​Dehydroprogesterone. This product is intended for research and analytical applications. 16-Dehydroprogesterone is a steroidal progestin.
    16-​Dehydroprogesterone (Standard)
  • HY-108979

    Progesterone Receptor Endocrinology
    Medrogestone is an orally active Progestin. Medrogestone shows a marked local progestational effect. Medrogestone maintains pregnancy in ovariectomized rats. Medrogestone inhibits ovulation. Medrogestone prevents pregnancy. Medrogestone produces a significant reduction in the severity of benign prostatic hypertrophy .
    Medrogestone

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: