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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
112 Results for "
protein A+G
" in MedChemExpress (MCE) Product Catalog:
Products (112)
112 Results for "protein A+G" in MCE Product Catalog:
1434
1434 Publications Verification
Art. -Nr.: HY-K0202
MCE Protein A/G Magnetic Beads provide a fast and convenient method for Immunoprecipitation, Co-Immunoprecipitation and Chromatin Immunoprecipitation. The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
52
52 Cited Publications
Synonyms: AG014699; PF-01367338
Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research .
51
51 Cited Publications
Synonyms: AG-014699 phosphate; PF-01367338 phosphate
Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research .
42
42 Cited Publications
Synonyms: AG014699 monocamsylate; PF-01367338 monocamsylate
Rucaparib (AG014699) monocamsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib monocamsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib monocamsylate has the potential for castration-resistant prostate cancer (CRPC) research .
37
9
9 Cited Publications
Art. -Nr.: HY-P74583
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A9; 60B8AG; Prev. CAGB; CGLB; Prev. CFAG; MIF; MRP-14; NIF; MRP14; protein S100-A9; P14; Calgranulin B; Migration Inhibitory Factor-Related protein 14; S100 Calcium-Binding protein A9 (Calgranulin B); Leukocyte L1 Complex Heavy Chain; S100 Calcium-Bin
Species:
Mouse
Source:
E. coli
5
3
Target:
Forschungsgebiete:
Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency .
2
2 Cited Publications
Art. -Nr.: HY-P71076
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone protein Band A; Prev. CFAG; protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding protein A8; Migration Inhibitory Factor-Related protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprotectin L1L Subunit; MA387; Cystic Fibrosis Antigen; L1Ag; S100-A8; NIF; 60B8AG; S100 Calcium Binding protein A8; CGLA; S100A9; 60B8AG; Prev. CAGB; CGLB; Prev. CFAG; MIF; MRP-14; NIF; MRP14; protein S100-A9; P14; Calgranulin B; Migration Inhibitory Factor-Related protein 14; S100 Calcium-Binding protein A9 (Calgranulin B); Leukocyte L1 Complex Heavy Chain; S100 Calcium-Binding protein A9; Calprotectin L1H Subunit; Calgranulin-B; S100-A9; L1AG; MAC387; S100 Calcium Binding protein A9; LIAG
Species:
Human
Source:
E. coli
2
2 Cited Publications
Art. -Nr.: HY-P70532
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A9; 60B8AG; Prev. CAGB; CGLB; Prev. CFAG; MIF; MRP-14; NIF; MRP14; protein S100-A9; P14; Calgranulin B; Migration Inhibitory Factor-Related protein 14; S100 Calcium-Binding protein A9 (Calgranulin B); Leukocyte L1 Complex Heavy Chain; S100 Calcium-Binding protein A9; Calprotectin L1H Subunit; Calgranulin-B; S100-A9; L1AG; MAC387; S100 Calcium Binding protein A9; LIAG
Species:
Human
Source:
E. coli
1
1 Cited Publications
Synonyms: Tyrphostin B66; AG 528
Tyrphostin AG 528 is an inhibitor of EGFR and ErbB2 with IC50s of 4.9 and 2.1 μM, respectively.
Tyrphostin AG 528 (Tyrphostin B66) is a protein tyrosine kinase inhibitor, with IC50s of 4.9 μM for epidermal growth factor receptors (EGFR) and 2.1 μM for ErbB2 . Tyrphostin AG 528 is also an anticancer agent .
1
1 Cited Publications
Art. -Nr.: HY-P7466
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AGR3; Anterior Gradient protein 3; Anterior Gradient 3, protein Disulphide Isomerase Family Member; AG-3; BCMP11; AG3; PDIA18; Anterior Gradient 3 Homolog (Xenopus Laevis); HAG-3; Anterior Gradient protein 3 Homolog; protein Disulfide Isomerase Family A,
Species:
Human
Source:
HEK293
1
1 Cited Publications
Art. -Nr.: HY-P72720
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD58; Ag3; Prev. LFA3; CD58 Antigen; CD58 Antigen, (Lymphocyte Function-Associated Antigen 3); CD58 protein; Lymphocyte Function-Associated Antigen 3; LFA-3; Surface Glycoprotein LFA-3; CD58 Molecule; CD58 Antigen, (Lymphocyte Function-Associated Antigen
Species:
Human
Source:
HEK293
Art. -Nr.: HY-119715
CAS. Nr.: 486414-35-1
Forschungsgebiete:
AG-012986 is a pan-CDK inhibitor with Ki values of 44 nM (CDK1), 9.2 nM (CDK4), 94 nM (CDK2), and IC50 values of 22 nM (CDK5), 4 nM (CDK9). AG-012986 causes apoptosis of T-cells by targeting upstream kinases in the p38 Mitogen-activated protein kinase (MAPK) pathway and impairing cellular survival. AG-012986 induces cell cycle arrest, retinoblastoma protein hypophosphorylation, and reduces Ki-67 expression. AG-012986 exerts antiproliferative activity in tumor cells, demonstrates antitumor efficacy in human xenograft models, and causes retinal and peripheral neurotoxicity, plus immune cell toxicity. AG-012986 can be used for the research of colon carcinoma, non-small cell lung carcinoma, lung carcinoma, breast carcinoma, ovarian tumor, pancreatic carcinoma, osteosarcoma, lymphoma, leukemia, retinotoxicity .
Art. -Nr.: HY-121012
CAS. Nr.: 442656-02-2
Forschungsgebiete:
(rac)-AG-205 is a potent inhibitor of progesterone receptor membrane component 1 (Pgrmc1) that induces genes involved in sterol synthesis, including the INSIG1 protein, which forms a complex with PGRMC1. (rac)-AG-205 prevents neuronal resistance to hypoxic ischaemia by blocking NF-kB signalling and activation of the BDNF/PI3K/AKT pathway .
Art. -Nr.: HY-P991664
Forschungsgebiete:
Art. -Nr.: HY-121663
CAS. Nr.: 400863-77-6
Target:
Forschungsgebiete:
ST-148 is a novel small molecule compound that has potent inhibitory effects against all four dengue virus serotypes. In the nonlethal AG129 mouse dengue virus infection model, ST-148 significantly reduced viremia and viral load in vital organs and tended to reduce plasma cytokine levels. Compound resistance was associated with the dengue virus capsid (C) gene, and the direct interaction of ST-148 with the C protein was presumed to be achieved through the protein's built-in fluorescence change in the presence of the compound. Therefore, ST-148 appears to interact with the dengue virus C protein and inhibit one or more unique steps of the viral replication cycle.
Art. -Nr.: HY-102003A
CAS. Nr.: 1327258-57-0
Synonyms: AG014699 camsylate; PF-01367338 camsylate
Rucaparib (AG014699) camsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib camsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib camsylate has the potential for castration-resistant prostate cancer (CRPC) research .
Art. -Nr.: HY-10617B
CAS. Nr.: 773059-19-1
Synonyms: AG014699 hydrochloride; PF-01367338 hydrochloride
Rucaparib (AG014699) hydrochloride is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib hydrochloride is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib hydrochloride has the potential for castration-resistant prostate cancer (CRPC) research .
Art. -Nr.: HY-10617C
CAS. Nr.: 773059-22-6
Synonyms: AG-014699 tartrate; PF-01367338 tartrate
Rucaparib (AG014699) tartrate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib tartrate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib tartrate has the potential for castration-resistant prostate cancer (CRPC) research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
