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Results for "

pyridine nucleotide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (1) Endogenous Metabolite (1)
By Research Areas:	Metabolic Disease (2)

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Targets Recommended: HCN Channel SOS1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-65008

N-Demethylricinine	Others	Others
N-Demethylricinine is a ricinine, can be interconverted with ricinine in senescent and green castor plant leaves. Ricinine, is a α-pyridone alkaloid biosynthetically related to the pyridine nucleotide cycle. The alkaloid catabolism of ricinine is associated with aging process .

HY-165175

(+)-Decanoylcarnitine	Drug Derivative	Metabolic Disease
(+)-Decanoylcarnitine is an (S)-acylcarnitine derivative and a potent inhibitor of carnitine-acylcarnitine translocase, with an IC₅₀ of 5 μM. (+)-Decanoylcarnitine acts as a competitive inhibitor of long-chain acylcarnitine transferase and (-)-carnitine palmityltransferase. (+)-Decanoylcarnitine blocks hepatic fatty acid oxidation, ketogenesis, oleate-induced activation of gluconeogenesis, as well as associated changes in acetyl-CoA, citrate, redox pair ratios, flavins and pyridine nucleotides. (+)-Decanoylcarnitine reverses ketosis in vivo, enhances insulin-mediated hypoglycemic effects in anesthetized animals, and reduces plasma ketone body levels when used in combination with insulin. (+)-Decanoylcarnitine can be used in studies related to diabetic ketoacidosis .

HY-P2759B

Thioredoxin Reductase (NADPH), Yeast	Endogenous Metabolite	Metabolic Disease
Thioredoxin reductase (TrxR/NTR), an enzyme belonging to the flavoprotein family of pyridine nucleotide-disulfide oxidoreductases. Thioredoxin reductase (TrxR), a component of the thioredoxin system, including thioredoxin (Trx) and NADPH, catalyzes the transfer of electrons from NADPH to Trx, acts as a reductant of disulfide-containing proteins and participates in the defense system against oxidative stresses.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-65008

N-Demethylricinine	Alkaloids Ricinus communis L. Euphorbiaceae Plants	Others
N-Demethylricinine is a ricinine, can be interconverted with ricinine in senescent and green castor plant leaves. Ricinine, is a α-pyridone alkaloid biosynthetically related to the pyridine nucleotide cycle. The alkaloid catabolism of ricinine is associated with aging process .

Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (2) mouse (1) rat (1) Rat (2) Mouse (2) human (1)
Application:	IHC-P (2) ICC/IF (2) IF-Tissue (2) IP (2) WB (3) ELISA (2)
Isotype:	IgG (1) IgG2 (1) IgG2b (1)
Conjugation:	Non-conjugated (3)
Clonality:	Polyclonal (1) Monoclonal (1)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P89413

	NNT Antibody Nicotinamide nucleotide transhydrogenase, pyridine nucleotide transhydrogenase, NNT	WB	Human, Mouse, Rat
	NNT Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to NNT.

HY-P89594

	NNT Antibody (YA8938) Nicotinamide nucleotide transhydrogenase, pyridine nucleotide transhydrogenase, NNT	WB, ICC/IF, IF-Tissue, IHC-P, IP, ELISA	human, mouse, rat
	NNT Antibody (YA8938) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to NNT.

HY-P810348

	NNT Antibody (YA9670) NAD(P) transhydrogenase, mitochondrial, NNT, Nicotinamide nucleotide transhydrogenase, pyridine nucleotide transhydrogenase,NAD(P) transhydrogenase, mitochondrial	WB, ICC/IF, IF-Tissue, IHC-P, IP, ELISA	Human, Mouse, Rat
	NNT Antibody (YA9670) is a Mouse-derived and non-conjugated IgG2 Monoclonal antibody, targeting to NNT.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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pyridine nucleotide

Inhibitors & Agonists

NaturalProducts

Antibodies

Natural
Products