![2,4,7-Trichloro-8-fluoropyrido[4,3-d]pyrimidine](https://file.medchemexpress.com/product_pic/hy-w095670.gif "Click to View 2,4,7-Trichloro-8-fluoropyrido[4,3-d]pyrimidine Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
pyridopyrimidines
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "pyridopyrimidines" in MCE Product Catalog:
Cat. No.: HY-W095670
CAS No.: 2454396-80-4
Target:
Research Areas:
2,4,7-Trichloro-8-fluoropyridopyrimidine is a pyridopyrimidine synthetic intermediate of MRTX1133 (HY-134813), which can be used for the synthesis of non-covalent KRAS G12D inhibitors .
Cat. No.: HY-159474
CAS No.: 3030576-47-4
KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R .
Cat. No.: HY-W061614
CAS No.: 681128-51-8
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Research Areas:
Cat. No.: HY-159474A
CAS No.: 3030576-46-3
(1R)-KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R .
Cat. No.: HY-159475
CAS No.: 3030577-05-7
KRAS inhibitor-25 (compound 151a) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM against KRas G12V, KRas WT and KRas G12R .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
