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Cat. No.: HY-162971

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KRAS inhibitor-33

KRAS inhibitor-33 (compound 115a) is an inhibitor of pyridopyrimidine kras (IC₅₀ ≤ 100nM).

For research use only. We do not sell to patients.

Formula: C₃₃H₃₉ClF₂N₆O₃
Molecular Weight:641.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

KRAS inhibitor-33 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

KRAS inhibitor-33 (compound 115a) is an inhibitor of pyridopyrimidine kras (IC₅₀ ≤ 100nM)^[1].

All Ras Isoforms :

Chemical Information

Molecular Weight 641.15
Formula C₃₃H₃₉ClF₂N₆O₃
SMILES

O=C1CCCCC2=C(C3=C(C4=NC(OC[C@@]56CCCN5C[C@@H](C6)F)=NC(N7CCCC(C7)CCN1)=C4C=N3)F)C=C(C=C2Cl)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. James Paul LAJINESS, et al. Pyridopyrimidine kras inhibitors. WO2024040131A1. 2023.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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KRAS inhibitor-33

All Ras Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

KRAS inhibitor-33 Related Classifications

HY-162971 Related Classifications