2 Results for "

rabbit PR

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "rabbit PR" in MCE Product Catalog:

Cat. No.: HY-106827
CAS No.: 74513-62-5
Synonyms: RU 27987
Trimegestone (RU 27987) is an orally active, selective progestogen and PR ligand, with an IC50 of 7.6 nM for hPR, 4.4 nM for rabbit PR, and 3.3 nM for rat PR. Trimegestone induces Alkaline phosphatase activity. Trimegestone exhibits antiandrogenic activity (IC50 = 303 nM). Trimegestone can be used in research related to menopausal symptoms and osteoporosis .
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Cat. No.: HY-16290
CAS No.: 211254-73-8
Synonyms: ZK 230211; BAY86 5044
Target:  

Progesterone Receptor

Research Areas:  

Endocrinology

Lonaprisan (ZK 230211; BAY86 5044) is an antagonist for progesterone receptor, with IC50 of 3.6 pM and 2.5 pM for PR-A and PR-B, respectively. Lonaprisan exhibits antiprogestagenic activity in rabbits, interrupts early pregnancy in rats, and exhibits antitumor efficacy against DMBA (HY-W011845)-induced mammary tumor. Lonaprisan reveals antiglucocorticoid and antiandrogenic effect .
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