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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
solid-phase oligonucleotide synthesis
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "solid-phase oligonucleotide synthesis" in MCE Product Catalog:
Cat. No.: HY-46317
CAS No.: 105931-57-5
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DMT-5Me-dC(Bz)-CE Phosphoramidite is a chemical structural unit that can be used in solid-phase DNA synthesis. DMT-5Me-dC(Bz)-CE Phosphoramidite can introduce the 5-methylcytidine base into the DNA chain to enhance its stability and binding affinity. DMT-5Me-dC(Bz)-CE Phosphoramidite can be used to construct modified oligonucleotides, especially for constructing locked nucleic acids (LNA) .
Cat. No.: HY-21648
CAS No.: 199593-09-4
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2'-OMe-Ac-C Phosphoramidite is a modified phosphoramidite that can be used for oligonucleotide synthesis .
Cat. No.: HY-W008848
CAS No.: 93183-15-4
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DMTr-LNA-5MeU-3-CED-phosphoramidite is a Phosphoramidite derivative and Nucleoside derivative .
Cat. No.: HY-W570887
CAS No.: 206055-79-0
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LNA-A (Bz) amidite is a phosphoramidite monomer applicable for oligonucleotide synthesis, such as the synthesis of miniature LNA anti-miRNA-122 antisense oligonucleotides .
Cat. No.: HY-78574
CAS No.: 13089-48-0
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N-Benzoylcytidine is a modified cytidine analogue that can be phosphorylated by uracil-cytidine kinase (UCK1 and UCK2). N-Benzoylcytidine can be used to synthesize 2-OH protective groups for solid-phase RNA synthesis, as well as synthetic oligonucleotides for UV induction and targeted gene silencing in zebrafish embryos .
Cat. No.: HY-W008848S
CAS No.: 2483830-16-4
Cat. No.: HY-W1119950
CAS No.: 1644649-86-4
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3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite is an adenine nucleotide monomer precursor used in solid-phase synthesis of oligonucleotides, particularly modified oligonucleotides, such as those with DNA chain end modifications. 3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite, with trityl (Tr), cyanoethyl (CE), and dimethylformamidine (DMF) protecting groups, is a ddNTP adenosine nucleoside useful in applications such as solid-phase oligonucleotide synthesis, probe design, and chain-termination sequencing .
Cat. No.: HY-W1061585
CAS No.: 136949-85-4
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DNP Phosphoramidite is a non-nucleoside-based phosphoramidite carrying a 2,4-dinitrophenyl (DNP) hapten group, which enables multiple labeling of oligonucleotides during solid-phase synthesis. DNP Phosphoramidite binds to anti-DNP antibodies, allowing the detection of labeled oligonucleotides via enzyme-linked colorimetric techniques .
Cat. No.: HY-185910
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Palmitamido-C7 CE-Phosphoramidite is a long-chain esterified phosphoramidite monomer used for solid-phase oligonucleotide synthesis. Palmitamido-C7 CE-Phosphoramidite is formed by linking palmitamido to the active end of 2-cyanoethyl phosphoramidite via a C7 alkyl spacer arm. Palmitamido-C7 CE-Phosphoramidite can be used as a building block for nucleic acid chemical modification to synthesize ester-coupled oligonucleotides.
Cat. No.: HY-W008848S1
Cat. No.: HY-182934
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Cy5 MMTr CPG 1000 is a type of fluorescently labeled solid-phase carrier used for the automated synthesis of solid-phase oligonucleotides. During the synthesis process, the Cy5 fluorescent dye can be directly covalently attached to the 3′-end of the oligonucleotide without the need for subsequent liquid-phase labeling. Cy5 MMTr CPG 1000 can be used for the synthesis of 3′-Cy5 labeled oligonucleotides.
Cat. No.: HY-185901
Cat. No.: HY-185906
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DBCO Phosphoramidite is a phosphoramidite reagent containing a dibenzocyclooctyne (DBCO) moiety, which can introduce a strain-promoted alkyne group for copper-free click chemistry into DNA strands during solid-phase oligonucleotide synthesis. DBCO Phosphoramidite is applicable to studies related to oligonucleotide modification, copper-free click conjugation, and functionalized DNA nanomaterials .
Cat. No.: HY-P11685
CAS No.: 2245800-85-3
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Cat. No.: HY-185911
Amino-modifier C6 dC(N-Bz) Phosphoramidite is a modified deoxycytidine synthesis monomer featuring an amino group attached via a six-carbon spacer arm. Amino-modifier C6 dC(N-Bz) Phosphoramidite allows for the site-specific incorporation of an amino group during the solid-phase synthesis of DNA oligonucleotides, enabling conjugation with functional moieties—such as fluorescent groups, peptides, or biotin—to produce functional nucleic acid probes.
Cat. No.: HY-185907
CAS No.: 1772522-17-4
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5'-Octyltocopherol C8 CE Phosphoramidite is a tocopherol-based phosphoramidite modification monomer for solid-phase oligonucleotide synthesis, which can introduce an octyltocopherol modification group with a C8 spacer arm at the 5'-end of oligonucleotides. 5'-Octyltocopherol C8 CE Phosphoramidite can be used to prepare DNA or RNA with hydrophobic tocopherol terminal modifications. 5'-Octyltocopherol C8 CE Phosphoramidite is applicable to studies related to oligonucleotide chemical synthesis, nucleic acid hydrophobic modification, and nucleic acid conjugate construction.
Cat. No.: HY-W1119956
CAS No.: 3103531-71-8
Synonyms: 5'(E)-VP-2'-OMe-iBu-G
Phosphoramidite
Research Areas:
5'-(E)-VPG Phosphoramidite (5'(E)-VP-2'-OMe-iBu-GPhosphoramidite) is a structurally modified phosphoramidite reagent used to synthesize biologically stable oligonucleotides. 5'-(E)-VPG Phosphoramidite (POM) carries a VP protecting group and can be coupled to the target oligonucleotide at the 5' end via solid-phase synthesis. The modified oligonucleotide is then constructed through oxidation and deprotection steps. 5'-(E)-VPG Phosphoramidite is suitable for RNAi and viral replication research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
