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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
synovitis
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "synovitis" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-N2435
CAS No.: 36700-45-5
3
3 Cited Publications
Synonyms: Cerulomycin; Caerulomycin
Category:
Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Disease Research Antibacterial Anticancer Disease Research Fields Inflammation/Immunology Other Antibiotics
Target:
Cat. No.: HY-P99368
CAS No.: 1831128-32-5
Synonyms: MCS110
Target:
Research Areas:
Research Areas:
GB83 is a potent PAR2 antagonist. GB83 reverses neutrophil elastase‐induced synovitis and pain. GB83 blocks the effect of MET-1 supernatant on NG neurons .
Cat. No.: HY-N2435R
CAS No.: 36700-45-5
Target:
Cat. No.: HY-184506
Research Areas:
R4VPL3-1 is a PROTAC-like degrader that simultaneously targets RNF4 and VHL, and also acts as a ferroptosis inducer. R4VPL3-1 induces iron-dependent lipid peroxidation and ferroptosis-mediated rapid cell death in cancer cells. R4VPL3-1 is applicable to research on human melanoma, human cutaneous squamous cell carcinoma, metastatic human sarcoma, malignant peripheral nerve sheath tumor, pigmented villonodular synovitis, undifferentiated pleomorphic sarcoma, myxofibrosarcoma, and lung adenocarcinoma .
Cat. No.: HY-184508
Target:
Research Areas:
E3 ligase Ligand 81 is a VHL E3 ubiquitin ligase ligand and constitutes the VHL ligand moiety of R4VPL3-1 (HY-184506). R4VPL3-1 is a PROTAC-like bifunctional degrader linking RNF4 and VHL; it binds to and modifies GPX4, thereby inhibiting its anti-ferroptotic function. R4VPL3-1 induces iron-dependent lipid peroxidation and rapid ferroptosis-mediated cell death in cancer cells. E3 ligase Ligand 81 can be used in research related to targeted protein degradation and tumors such as melanoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
