[8]-Shogaol (Standard)
Based on 1 publication(s) in Google Scholar
-Shogaol (Standard) is the analytical standard of -Shogaol. This product is intended for research and analytical applications. -Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC50=5 μM), anti-cancer and anti-inflammatory activity. -Shogaol inhibited COX-2 (IC50=17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC50=5 μM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA).
For research use only. We do not sell to patients.
- CAS No.: 36700-45-5
- Formula: C19H28O3
- Molecular Weight:304.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
![[8]-Shogaol (Standard) Chemical Structure](https://file.medchemexpress.com/product_pic/hy-n2435r.gif "Click to View [8]-Shogaol (Standard) Chemical Structure")
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Product Information
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Chemical Information
- Purity & Documentation
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Publications Citing Use of MedChemExpress (MCE) [8]-Shogaol (Standard)
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Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 36700-45-5
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Molecular Weight 304.42
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Formula C19H28O3
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SMILES
CCCCCCC/C=C/C(CCC1=CC=C(O)C(OC)=C1)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Purity & Documentation
References
[1]. Shieh PC, et al. Induction of apoptosis by [8]-shogaol via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia cells. J Agric Food Chem. 2010 Mar 24;58(6):3847-54. [Content Brief]
[2]. van Breemen RB, et al. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 2011 Jan;82(1):38-43. [Content Brief]
[3]. Nurtjahja-Tjendraputra E, et al. Effective anti-platelet and COX-1 enzyme inhibitors from pungent constituents of ginger. Thromb Res. 2003;111(4-5):259-65. [Content Brief]
[4]. Jo S, et al. 8-Shogaol inhibits rheumatoid arthritis through targeting TAK1. Pharmacol Res. 2022 Apr;178:106176. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
[8]-Shogaol (Standard) Related Classifications
HY-N2435R Related Classifications
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