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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
tetrahydroisoquinoline compound
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "tetrahydroisoquinoline compound" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W705106
CAS No.: 3422-42-2
Synonyms: (-)-(S)-Coclaurine hydrochloride; L-Coclaurine hydrochloride
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Cat. No.: HY-148480
CAS No.: 2728780-74-1
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Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4) .
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Tetrahydropapaverine hydrochloride is a tetrahydroisoquinoline (TIQ) compound with inhibitory effects on tryptophan hydroxylase (TPH) (IC50 = 5.7 μM). Tetrahydropapaverine hydrochloride decreases intracellular serotonin content in murine mastocytoma P815 cells, with an IC50 value of 6.2 μM. Tetrahydropapaverine hydrochloride can be used for studies on potential neurotoxicity in monoaminergic neurons .
KRAS inhibitor-10 selectively and effectively inhibit RAS proteins, and particularly KRAS proteins. KRAS inhibitor-10 is an orally active anti-cancer agent and can be used for cancer research, such as pancreatic cancer, breast cancer, multiple myeloma, leukemia and lung cancer. KRAS inhibitor-10 is a tetrahydroisoquinoline compound (compound 11) extracted from patent WO2021005165 A1 .
Cat. No.: HY-60308A
CAS No.: 57196-62-0
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6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-42318
CAS No.: 1870821-29-6
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(S)-4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-113969
CAS No.: 61563-24-4
Category:
Alkaloids Neurological Disease Endogenous metabolite Disease Research Fields Isoquinoline Alkaloids
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Cat. No.: HY-156079
CAS No.: 1071049-42-7
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Antidepressant agent 5 (Compound 3i) is a 7-substituted tetrahydroisoquinolines derivatives. Antidepressant agent 5 exhibits almost equal antidepressant activity compared with magnoflorine. ntidepressant agent 5 can be used for depressive disorder research .
Cat. No.: HY-W045121
CAS No.: 933752-32-0
Cat. No.: HY-164726
CAS No.: 96719-63-0
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Estrogen receptor modulator 11 (Compound 27) is a tetrahydroisoquinoline derivative. Estrogen receptor modulator 11 has a certain affinity for estrogen receptors (ER), with IC50 values of 285 nM and 421 nM for ERα and ERβ, respectively. Estrogen receptor modulator 11 lacks antagonist activity in the MCF-7 cellular assay .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
