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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
101 Results for "
thioesterase
" in MedChemExpress (MCE) Product Catalog:
Products (101)
101 Results for "thioesterase" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: GNF-Pf-1127
Target:
Research Areas:
ML348 (GNF-Pf-1127) is a selective and reversible acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM, and barely inhibits LYPLA2 .
8
8 Cited Publications
Target:
Research Areas:
ML349 is a potent and specific acyl protein thioesterase 2(APT2)/lysophospholipase 2 (LYPLA2) inhibitor with a Ki of 120 nM. ML349 is also an inhibitor of LYPLA2 with an IC50 of 144 nM .
6
3
Research Areas:
Ezurpimtrostat (GNS561) is an orally active PPT1 inhibitor, autophagy inhibitor, immunomodulator, anti-inflammatory agent, and anticancer agent. Ezurpimtrostat inhibits PPT1, dysregulates lysosomal function, redistributes mTOR, and induces apoptosis. Ezurpimtrostat reduces IFN‑α, CRP, immune complex deposition, and SARS‑CoV‑2 viral load. Ezurpimtrostat can be used for the study of systemic lupus erythematosus, SARS‑CoV‑2, hepatocellular carcinoma, fibrosis, and related disorders .
1
1 Cited Publications
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P71230
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPT1; INCL; Prev. PPT; Ceroid-Lipofuscinosis, Neuronal 1, Infantile; CLN1; PPT-1; Palmitoyl-Protein Hydrolase 1; Palmitoyl-Protein thioesterase 1; Ceroid-Palmitoyl-Palmitoyl-Protein thioesterase 1
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P700622
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPT1; INCL; Prev. PPT; Ceroid-Lipofuscinosis, Neuronal 1, Infantile; CLN1; PPT-1; Palmitoyl-Protein Hydrolase 1; Palmitoyl-Protein thioesterase 1; Ceroid-Palmitoyl-Palmitoyl-Protein thioesterase 1
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P701447
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: USP28; Ubiquitin Specific Peptidase 28; Ubiquitin-Specific-Processing Protease 28; Ubiquitin Carboxyl-Terminal Hydrolase 28; Deubiquitinating Enzyme 28; Ubiquitin thioesterase 28; KIAA1515; Ubiquitin Carboxyl-Terminal Hydrolase; Ubiquitin Specific Proteas
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P702063
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: USP11; Ubiquitin Specific Peptidase 11; UHX1; Ubiquitin Carboxyl-Terminal Hydrolase 11; Deubiquitinating Enzyme 11; Ubiquitin thioesterase 11; Ubiquitin Carboxyl-Terminal Hydrolase, X-Linked; Ubiquitin-Specific Processing Protease 11; Ubiquitin-Specific-P
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P702603
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP7; HAUSP; Ubiquitin Specific Peptidase 7; Ubiquitin-Specific-Processing Protease 7; Ubiquitin Carboxyl-Terminal Hydrolase 7; Deubiquitinating Enzyme 7; Ubiquitin thioesterase 7; Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated); Herpesvirus-Asso
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P74478
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP7; HAUSP; Ubiquitin Specific Peptidase 7; Ubiquitin-Specific-Processing Protease 7; Ubiquitin Carboxyl-Terminal Hydrolase 7; Deubiquitinating Enzyme 7; Ubiquitin thioesterase 7; Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated); Herpesvirus-Asso
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P703232
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: USP4; Ubiquitin Specific Peptidase 4; UNP; Unph; Ubiquitin Specific Peptidase 4 (Proto-Oncogene); Ubiquitin Carboxyl-Terminal Hydrolase 4; Ubiquitous Nuclear Protein Homolog; Deubiquitinating Enzyme 4; Ubiquitin thioesterase 4; Ubiquitin Specific Protease
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P701411
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP15; Ubiquitin Specific Peptidase 15; KIAA0529; UNPH4; Ubiquitin-Specific-Processing Protease 15; Ubiquitin Carboxyl-Terminal Hydrolase 15; Deubiquitinating Enzyme 15; Ubiquitin thioesterase 15; Ubiquitin Specific Protease 15; Ubiquitin Thiolesterase 15
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P701450
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP30; Ubiquitin Specific Peptidase 30; Ubiquitin-Specific-Processing Protease 30; Ubiquitin Carboxyl-Terminal Hydrolase 30; Deubiquitinating Enzyme 30; Ubiquitin thioesterase 30; Ub-Specific Protease 30; MGC10702; FLJ40511; Ubiquitin Carboxyl-Terminal Hy
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P71115
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UCHL3; Ubiquitin C-Terminal Hydrolase L3; Ubiquitin Carboxyl-Terminal Esterase L3 (Ubiquitin Thiolesterase); Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3; Ubiquitin thioesterase L3; Ubiquitin Thiolesterase; UCH-L3; Ubiquitin Carboxyl-Terminal Hydrolas
Species:
Human
Source:
E. coli
Cat. No.: HY-18522
CAS No.: 1312782-34-5
Target:
Research Areas:
AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. AA26-9 shows inhibitory activity against approximately 1/3 of the 40+ serine hydrolases detected in immortalized T cell lines .
Cat. No.: HY-P10486
CAS No.: 200010-31-7
Cat. No.: HY-145519
CAS No.: 229644-17-1
Target:
Research Areas:
Mu-6S-Palm-β-Glc is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT). Mu-6S-Palm-β-Glc can be used for the research of neuronal ceroid lipofuscin disease in infants .
Research Areas:
S-Acetylglutathione is a glutathione derivative and intracellular glutathione supplement that bypasses glutathione synthetase deficiency through intracellular thioesterase conversion, exhibits higher blood stability than glutathione, and selectively induces apoptosis in lymphoma and malignant cells by inducing oxidative stress (apoptosis). S-Acetylglutathione can be used in research on glutathione synthetase deficiency, herpes simplex virus type 1 infection, murine AIDS, lymphoma, and malignant tumors .
Cat. No.: HY-P4909
CAS No.: 200010-29-3
Synonyms: AIP-I
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
