16 Results for "

thyroglobulin

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "thyroglobulin" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-B0558
CAS No.: 22232-54-8
Target:  

p38 MAPK

Research Areas:  

Neurological Disease Endocrinology

Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
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Cat. No.: HY-107903
CAS No.: 9010-34-8
Purity:  93%
Synonyms: thyroglobulin from bovine
Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle. Thyroglobulin activates Akt kinase activity in FRTL-5 thyroid cell .
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Cat. No.: HY-D0025
CAS No.: 106562-32-7
7-Amino-4-methylcoumarin-3-acetic acid (AMCA) serves as the parent structure of coumarin-based blue fluorescent dyes, and its activated form AMCA-NHS can directly conjugate with proteins (Ex/Em ≈ 350/440-460).
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Cat. No.: HY-114994
CAS No.: 541535-31-3
Purity:  ≥98.0%
Target:  

TSH Receptor

Research Areas:  

Endocrinology

MS437 is a potent TSH receptor (TSHR) stimulator with an EC50 value of 13x10 -8 M. MS437 shows potent activation of G, Gαq and 12 and up-regulation of thyroglobulin (Tg), sodium iodine symporter (NIS) and TSHR gene expressions .
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Cat. No.: HY-114918
CAS No.: 512840-45-8
Purity:  99.85%
Target:  

TSH Receptor

Research Areas:  

Endocrinology

MS438 is a potent thyrotropin receptor (TSHR) agonist with an EC50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice .
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Cat. No.: HY-149132
CAS No.: 1191043-85-2
Purity:  96.7%
Synonyms: DDA
Target:  

LXR

Dendrogenin A (DDA) is a ligand for liver X receptor (LXR), that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor, thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC50 of 4.1 and 6.2 µM. Dendrogenin A arrests the cell cycle at G0/G1 phase .
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Cat. No.: HY-P86004
Synonyms: thyroglobulin; Tg;

Host:  

Mouse

Application:  

IHC-P, ELISA

Reactivity:  

Human

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Cat. No.: HY-B0558S
Carbimazole-d5 is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
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Cat. No.: HY-W744953
Carbimazole-d3 is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
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Cat. No.: HY-B0558R
CAS No.: 22232-54-8
Carbimazole (Standard) is the analytical standard of Carbimazole. This product is intended for research and analytical applications. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
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Cat. No.: HY-P82454
Synonyms: thyroglobulin (Tg)

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

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Cat. No.: HY-P810363
Synonyms: AITD 3, AITD3, hTG, TDH3, Tg, TGN, THYG_HUMAN, thyroglobulin

Host:  

Rabbit

Application:  

WB, IHC-P, IF-Tissue

Reactivity:  

Human

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Cat. No.: HY-187255S
[U- 15N]-TG-domain2 is the 15N-labeled TG-domain2. Thyroglobulin (TG-domain 2) is involved in iodine binding and hormone modification, serving as an important biomarker for thyroid cancer, autoimmune thyroiditis, and thyroid dysfunction. This isotope-labeled form can be used in NMR studies to investigate disease mechanisms and in mass spectrometry analysis.
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Cat. No.: HY-187256S
[U- 15N]-TG-domain4 is the 15N-labeled TG-domain4. TG-domain 4, a key functional region of thyroglobulin (TG), is a significant biomarker associated with monitoring thyroid cancer recurrence, autoimmune thyroid diseases, and thyroid dysfunction. This isotope-labeled form can be used in NMR studies to investigate disease mechanisms and in mass spectrometry analysis.
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Cat. No.: HY-NP222
TG Protein, human is a dimeric glycoprotein produced by thyroid follicular cells that functions exclusively within the thyroid gland. It serves as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), while also storing iodine and inactive forms of thyroid hormones within the follicular lumen of thyroid follicles. Thyroglobulin can activate Akt kinase activity in FRTL-5 thyroid cells .
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Cat. No.: HY-P87077
Synonyms: bA270C4A.1 antibody; bA37D8.1 (secreted modular calcium binding protein 2) antibody; bA37D8.1 antibody; dJ421D16.1 (novel thyroglobulin type 1 repeat containing protein) antibody; dJ421D16.1 antibody; MST117 antibody; MSTP117 antibody; MSTP140 antibody; Secreted modular calcium binding protein 2 antibody; Secreted modular calcium-binding protein 2 antibody

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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