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trehalose monomycolate synthesis

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101867
    AU1235
    3 Publications Verification

    		 Bacterial Infection Cancer
    AU1235, an adamantyl urea, is a potent MmpL3 inhibitor. The Mycobacterium tuberculosis protein MmpL3 performs an essential role in cell wall synthesis, since it effects the transport of trehalose monomycolates across the inner membrane .
    AU1235
  • HY-181283
    MSU-43557

    		Bacterial Infection
    MSU-43557 is a Mycobacterium abscessus MmpL3 (MAB_4508) inhibitor and bactericidal agent. MSU-43557 inhibits MmpL3 function, disrupts trehalose monomycolate synthesis, and reduces biofilm-associated Mycobacterium abscessus viability. MSU-43557 exerts bactericidal activity against intracellular Mycobacterium abscessus. MSU-43557 shows low eukaryotic cytotoxicity and low Mycobacterium abscessus resistance frequency. MSU-43557 can be used for the research of mycobacterium abscessus infection .
    MSU-43557
  • HY-101867R
    AU1235 (Standard)

    		Reference Standards Bacterial Infection Cancer
    AU1235 (Standard) is the analytical standard of AU1235 (HY-101867). This product is intended for research and analytical applications. AU1235, an adamantyl urea, is a potent MmpL3 inhibitor. The Mycobacterium tuberculosis protein MmpL3 performs an essential role in cell wall synthesis, since it effects the transport of trehalose monomycolates across the inner membrane .
    AU1235 (Standard)

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