331 Results for "

triterpene ester

" in MedChemExpress (MCE) Product Catalog:
Products (331)

331 Results for "triterpene ester" in MCE Product Catalog:

19
Asiaticoside
Asiaticoside
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19 Publications Verification
Cat. No.: HY-N0439
CAS No.: 16830-15-2
Category:  

Cardiovascular Disease Triterpenes Neurological Disease Centella asiatica (L.) Urb. Plants Endogenous metabolite Terpenoids Umbelliferae Disease Research Fields Cancer

Target:  

p38 MAPK TGF-beta/Smad Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite

Asiaticoside, a trisaccaride triterpene from Centella asiatica, suppresses TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts; Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties.
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12
Saikosaponin D
Saikosaponin D
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12 Cited Publications
Cat. No.: HY-N0250
CAS No.: 20874-52-6
Category:  

Infection Triterpenes Terpenoids Plants Umbelliferae Disease Research Fields Inflammation/Immunology Carphephorus corymbosus (Nutt.) Torr. & A.Gray

Target:  

STAT NF-κB Estrogen Receptor/ERR Bacterial

Saikosaponin D is a triterpene saponin isolated from Bupleurum, with anti-inflammatory, anti-bacterial, anti-tumor, and anti-allergic activities; Saikosaponin D inhibits selectin, STAT3 and NF-kB and activates estrogen receptor-β.
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5
Betulonic acid
Betulonic acid
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5 Cited Publications
Cat. No.: HY-N1451
CAS No.: 4481-62-3
Synonyms: Betunolic acid; Liquidambaric acid; (+)-Betulonic acid
Category:  

Infection Triterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Parasite HSV

Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .
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5
Asiatic acid
Asiatic acid
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5 Cited Publications
Cat. No.: HY-N0194
CAS No.: 464-92-6
Category:  

Triterpenes Terpenoids Centella asiatica (L.) Urb. Plants Umbelliferae Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis Parasite

Asiatic acid, a pentacyclic triterpene found in Centella asiatica (Centella asiatica), has anticancer activity. Asiatic acid induces apoptosis in melanoma cells and has barrier protective effects on human aortic endothelial cells (HAEC). Asiatic acid also has anti-inflammatory activity and inhibits tumor necrosis factor (TNF)-α-induced endothelial barrier dysfunction. Asiatic acid also inhibits NLRP3 inflammasome activation and NF-κB pathway, effectively inhibits inflammation in rats, and has neuroprotective effects in rat spinal cord injury (SCI) model .
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3
Echinocystic acid
Echinocystic acid
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3 Cited Publications
Cat. No.: HY-N0271
CAS No.: 510-30-5
Category:  

Triterpenes Leguminosae Terpenoids Gleditsia sinensis Lam. Plants Disease Research Fields Cancer

Target:  

Reactive Oxygen Species (ROS) Apoptosis

Echinocystic acid is a natural pentacyclic triterpene with potent antioxidant, anti-inflammatory and analgesic activities .
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3
Madecassoside
Madecassoside
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3 Cited Publications
Cat. No.: HY-N0568
CAS No.: 34540-22-2
Synonyms: Asiaticoside A
Category:  

Triterpenes Terpenoids Other Diseases Centella asiatica (L.) Urb. Plants Umbelliferae Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Apoptosis Autophagy Keap1-Nrf2 p38 MAPK Caspase

Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB , exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity . Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.
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3
Sodium aescinate
Sodium aescinate
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3 Cited Publications
Cat. No.: HY-N1404
CAS No.: 20977-05-3
Category:  

Triterpenes Hippocastanaceae Terpenoids Aesculus hippocastanum Plants Disease Research Fields Inflammation/Immunology

Target:  

NF-κB

Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities . Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway .
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3
Panaxatriol
Panaxatriol
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3 Cited Publications
Cat. No.: HY-N0597
CAS No.: 32791-84-7
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Other Diseases Plants Disease Research Fields Araliaceae

Target:  

Akt Insulin Receptor Apoptosis Reactive Oxygen Species (ROS)

Panaxatriol is an orally active dammarane-type tetracyclic triterpene sapogenin. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer [1][2][3].
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2
Tormentic acid
Tormentic acid
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2 Cited Publications
Cat. No.: HY-N4137
CAS No.: 13850-16-3
Category:  

Cardiovascular Disease Triterpenes Terpenoids Rosaceae Plants Disease Research Fields Rosa rugosa Thunb.

Target:  

Others

Tormentic acid, a triterpene isolated from Rosa rugosa, exerts anti-inflammatory, antihyperlipidemic, and anti-atherogenic properties .
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2
Oleanonic acid
Oleanonic acid
0 Images
2 Cited Publications
Cat. No.: HY-N1487
CAS No.: 17990-42-0
Synonyms: 3-Oxooleanolic acid
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Cancer

Target:  

HIV Autophagy Ferroptosis Amyloid-β

Oleanonic acid (3-Oxooleanolic acid) is an orally available triterpene that has anti-inflammatory and insecticidal properties. In vitro, oleanonic acid can improve oxidative stress, autophagy defects, ferroptosis, mitochondrial damage, and endoplasmic reticulum stress induced by Amyloid-β, and in vivo, it can alleviate myocardial hypertrophy in rats .
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2
Nimbolide
Nimbolide
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2 Cited Publications
Cat. No.: HY-116035
CAS No.: 25990-37-8
Purity:  99.79%
Category:  

Triterpenes Terpenoids Plants Azadirachta indica A. Juss. Disease Research Fields Meliaceae Cancer

Target:  

Wnt NF-κB CDK Apoptosis

Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .
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2
Esculentoside A
Esculentoside A
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2 Cited Publications
Cat. No.: HY-N0632
CAS No.: 65497-07-6
Category:  

Triterpenes Terpenoids Phytolacca acinosa Roxb. Plants Disease Research Fields Inflammation/Immunology Phytolaccaceae

Target:  

COX NF-κB

Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .
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2
Astragaloside II
Astragaloside II
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2 Cited Publications
Cat. No.: HY-N0433
CAS No.: 84676-89-1
Synonyms: Astrasieversianin VIII
Category:  

Triterpenes Leguminosae Terpenoids Other Diseases Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants Disease Research Fields

Target:  

Autophagy Interleukin Related HIF/HIF Prolyl-Hydroxylase SOD NF-κB

Astragaloside II is an orally active Cycloartane-type triterpene glycoside. Astragaloside II can be extracted from Astragalus membranaceus. Astragaloside II inhibits Autophagy, decreases pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, p-IκB and increases SOD. Astragaloside II regulates immunity and reduces inflammatory responses. Astragaloside II can be used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis .
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1
Arnidiol
Arnidiol
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1 Cited Publications
Cat. No.: HY-N4165
CAS No.: 6750-30-7
Category:  

Triterpenes Terpenoids Dendranthema morifolium (Ramat.) Tzvel. Other Diseases Plants Compositae Disease Research Fields

Target:  

Others

Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn F. .
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1
Polyporusterone B
Polyporusterone B
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1 Cited Publications
Cat. No.: HY-N7693
CAS No.: 141360-89-6
Category:  

Polyporaceae Other Diseases Poria cocos Plants Disease Research Fields Steroids

Target:  

Others

Polyporusterone B is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone B has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .
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1
Pomolic acid
Pomolic acid
0 Images
1 Cited Publications
Cat. No.: HY-N6601
CAS No.: 13849-91-7
Synonyms: Randialic acid A
Category:  

Euscaphis japonica Triterpenes other families Staphyleaceae Terpenoids Plants Disease Research Fields Cancer

Target:  

Apoptosis

Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from?Euscaphis japonica?(Tunb.). Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC) .
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1
Gypenoside XLVI
Gypenoside XLVI
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1 Cited Publications
Cat. No.: HY-N6252
CAS No.: 94705-70-1
Category:  

Triterpenes Terpenoids Cucurbitaceae Plants Disease Research Fields Gynostemma pentaphyllum (Thunb.) Makino Cancer

Target:  

Others

Gypenoside XLVI is one of the major dammarane-type triterpenoid saponins from Gynostamma pentaphallum . Gypenoside XLVI has a tetracyclic triterpene structure and possess potent non-small cell lung carcinoma A549 cell inhibitory activity .
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1
Euscaphic acid
Euscaphic acid
0 Images
1 Cited Publications
Cat. No.: HY-N2566
CAS No.: 53155-25-2
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Cancer

Target:  

DNA/RNA Synthesis PI3K Apoptosis

Euscaphic acid, a DNA polymerase inhibitor, is a triterpene from the root of the R. alceaefolius Poir. Euscaphic inhibits calf DNA polymerase α (pol α) and rat DNA polymerase β (pol β) with IC50 values of 61 and 108 μM . Euscaphic acid induces apoptosis .
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1
Uvaol
Uvaol
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1 Cited Publications
Cat. No.: HY-N1109
CAS No.: 545-46-0
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis

Uvaol, a triterpene present in olives and virgin olive oil, possesses anti-inflammatory properties and antioxidant effects. Uvaol is an orally active inducer of apoptosis in astroglioma cells. Uvaol also has anti-cancer activities. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice .
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1
Absinthin
Absinthin
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1 Cited Publications
Cat. No.: HY-N0742
CAS No.: 1362-42-1
Category:  

Triterpenes Terpenoids Other Diseases Plants Acacia confusa Merr. Compositae Disease Research Fields

Target:  

Others

Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca 2+-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46 .
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