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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
tyrosine aminotransferase
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "tyrosine aminotransferase" in MCE Product Catalog:
1
Research Areas:
Flumethasone (Flumetasone) is an orally active, high selective and potent glucocorticoid receptor (GR) agonist. Flumethasone activates GR to inhibit nuclear factor kappa B (NF-κB)-mediated pro-inflammatory cytokine production (TNF-α, IL-1β) and promotes anti-inflammatory gene expression (IL-10), while also regulating metabolic enzyme activity (tyrosine aminotransferase induction). Flumethasone is promising for research of inflammatory diseases, cancer, and endocrine regulation .
Cat. No.: HY-W104477
CAS No.: 7423-96-3
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3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association .
Cat. No.: HY-W011458
CAS No.: 502481-30-3
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NSD 1034 is a potent inhibitor of aromatic L-amino acid decarboxylase (AADC) and tyrosine aminotransferase (TAT), with IC50 values of 0.32 μM and 80 μM, respectively. NSD 1034 increases dopamine synthesis and release by inhibiting AADC and TAT, and stimulating tyrosine hydroxylase in dopaminergic neurons via calcium influx in a classical dopamine receptor-independent manner. NSD 1034 is used in studies of Parkinson's disease and sleep disorders .
Cat. No.: HY-W725041
CAS No.: 403640-27-7
Methiozolin is an oxazoline herbicide designed for the selective control of annual bluegrass in turfgrass. Methiozolin strongly inhibits the biosynthesis of cellulose and hemicellulose in corn root cells at low concentrations. Methiozolin inhibits recombinant Arabidopsis thaliana tyrosine aminotransferase, with a IC50 of approximately 200 µM. Methiozolin not only effectively controls vegetative growth but also significantly suppresses inflorescence formation, which helps reduce the seed bank .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
