sEH inhibitor-10
sEH inhibitor-10 (Compound 37) is a selective soluble epoxide hydrolase (sEH) inhibitor (IC50=0.5 μM). sEH inhibitor-10 maintains high cycloeicosatrienoic acid (EETs) levels by inhibiting sEH, thereby reducing inflammation, regulating endothelial tone, improving mitochondrial function, and reducing oxidative stress. sEH inhibitor-10 has good research potential in metabolic, renal and cardiovascular diseases.
For research use only. We do not sell to patients.
- Formula: C22H22F3N3O2S
- Molecular Weight:449.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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sEH 0.5 μM (IC50) |
Chemical Information
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Molecular Weight 449.49
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Formula C22H22F3N3O2S
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SMILES
O=C(C1=CC(N=C(SCC2=CC=CC=C2C(F)(F)F)N3)=C(C=C1)C3=O)NCC(C)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)