Sofosbuvir impurity 3
Based on 1 Customer Validation
Sofosbuvir impurity 3 is an impurity of Sofosbuvir (HY-15005).
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 1496551-72-4
- Formula: C10H13ClN2O5
- Molecular Weight:276.68
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>100 μM
Compound: 5
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Cytotoxicity against human HuH7 cells assessed as reduction in cell viability
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability
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[PMID: 28835346] |
Chemical Information
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CAS No. 1496551-72-4
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Appearance Solid
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Molecular Weight 276.68
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Formula C10H13ClN2O5
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Color White to off-white
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SMILES
O=C(C=CN1[C@H]2[C@@](Cl)(C)[C@H](O)[C@@H](CO)O2)NC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (361.43 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (246 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6143 mL | 18.0714 mL | 36.1428 mL | 90.3571 mL |
| 5 mM | 0.7229 mL | 3.6143 mL | 7.2286 mL | 18.0714 mL | |
| 10 mM | 0.3614 mL | 1.8071 mL | 3.6143 mL | 9.0357 mL | |
| 15 mM | 0.2410 mL | 1.2048 mL | 2.4095 mL | 6.0238 mL | |
| 20 mM | 0.1807 mL | 0.9036 mL | 1.8071 mL | 4.5179 mL | |
| 25 mM | 0.1446 mL | 0.7229 mL | 1.4457 mL | 3.6143 mL | |
| 30 mM | 0.1205 mL | 0.6024 mL | 1.2048 mL | 3.0119 mL | |
| 40 mM | 0.0904 mL | 0.4518 mL | 0.9036 mL | 2.2589 mL | |
| 50 mM | 0.0723 mL | 0.3614 mL | 0.7229 mL | 1.8071 mL | |
| 60 mM | 0.0602 mL | 0.3012 mL | 0.6024 mL | 1.5060 mL | |
| 80 mM | 0.0452 mL | 0.2259 mL | 0.4518 mL | 1.1295 mL | |
| 100 mM | 0.0361 mL | 0.1807 mL | 0.3614 mL | 0.9036 mL |
Sofosbuvir impurity 3 Related Classifications
HY-I0514 Related Classifications
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