Squalene synthase-IN-1
Squalene synthase-IN-1 (compound 1) is a potent antihyperlipidemic agent acting through Squalene Synthase inhibition. Squalene synthase-IN-1 exhibits an outstanding antioxidant and anti-inflammatory activity. Squalene synthase-IN-1 displays a significant reduction not only of glucose but also of oxidative stress levels, while it did not cause any toxicity.
For research use only. We do not sell to patients.
- Formula: C17H19BrN2O2S
- Molecular Weight:395.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male ApoE−/− mice (10-12 weeks old, 24 to 28 g)[1]
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Dosage:56 μmols/kg (22.14 mg/kg)
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Administration:i.p.,twice daily
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Result:Displayed a powerful antihypercholesterolemic/antihyperlipidemic effect decreasing TC and LDL levels by 53% and 76%, respectively, and increasing HDL levels more than 100%.
Chemical Information
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Molecular Weight 395.31
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Formula C17H19BrN2O2S
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SMILES
CN1CCOC(O)(C2=CC=C(NC(C=CC=C3)=C3S4)C4=C2)C1.Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Squalene synthase-IN-1 Related Classifications
HY-149405 Related Classifications
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