1. JAK/STAT Signaling
    Stem Cell/Wnt
  2. STAT
  3. Stafia-1-dipivaloyloxymethyl ester

Stafia-1-dipivaloyloxymethyl ester 

Cat. No.: HY-136568
Handling Instructions

Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b.

For research use only. We do not sell to patients.

Stafia-1-dipivaloyloxymethyl ester Chemical Structure

Stafia-1-dipivaloyloxymethyl ester Chemical Structure

CAS No. : 2582755-72-2

Size Price Stock Quantity
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg USD 800 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b[1].

IC50 & Target[1]

STAT5a

 

In Vitro

Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: STAT5a-GFP-transfected K562 cells.
Concentration: 0-200 μM.
Incubation Time:
Result: Decreased pSTAT5a expression.
Molecular Weight

750.74

Formula

C₃₇H₄₈FO₁₃P

CAS No.
SMILES

O=C(C(C)(C)C)OCOP(OCOC(C(C)(C)C)=O)(C(C1=CC(C2=CC(OC)=C(OC)C(OC)=C2)=CC(C3=CC(OC)=C(C(OC)=C3)OC)=C1)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (133.20 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3320 mL 6.6601 mL 13.3202 mL
5 mM 0.2664 mL 1.3320 mL 2.6640 mL
10 mM 0.1332 mL 0.6660 mL 1.3320 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (3.33 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

Stafia-1-dipivaloyloxymethyl esterSTATpSTAT5a,Inhibitorinhibitorinhibit

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Product Name:
Stafia-1-dipivaloyloxymethyl ester
Cat. No.:
HY-136568
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