Stafia-1-dipivaloyloxymethyl ester
Based on 1 Customer Validation
Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b.
For research use only. We do not sell to patients.
- Purity: 95.38%
- CAS No.: 2582755-72-2
- Formula: C37H48FO13P
- Molecular Weight:750.74
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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STAT5a |
Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:STAT5a-GFP-transfected K562 cells.
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Concentration:0-200 μM.
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Incubation Time:
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Result:Decreased pSTAT5a expression.
Chemical Information
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CAS No. 2582755-72-2
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Appearance Oil
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Molecular Weight 750.74
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Formula C37H48FO13P
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Color White to light yellow
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SMILES
O=C(C(C)(C)C)OCOP(OCOC(C(C)(C)C)=O)(C(C1=CC(C2=CC(OC)=C(OC)C(OC)=C2)=CC(C3=CC(OC)=C(C(OC)=C3)OC)=C1)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (133.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.3320 mL | 6.6601 mL | 13.3202 mL | 33.3005 mL |
| 5 mM | 0.2664 mL | 1.3320 mL | 2.6640 mL | 6.6601 mL | |
| 10 mM | 0.1332 mL | 0.6660 mL | 1.3320 mL | 3.3300 mL | |
| 15 mM | 0.0888 mL | 0.4440 mL | 0.8880 mL | 2.2200 mL | |
| 20 mM | 0.0666 mL | 0.3330 mL | 0.6660 mL | 1.6650 mL | |
| 25 mM | 0.0533 mL | 0.2664 mL | 0.5328 mL | 1.3320 mL | |
| 30 mM | 0.0444 mL | 0.2220 mL | 0.4440 mL | 1.1100 mL | |
| 40 mM | 0.0333 mL | 0.1665 mL | 0.3330 mL | 0.8325 mL | |
| 50 mM | 0.0266 mL | 0.1332 mL | 0.2664 mL | 0.6660 mL | |
| 60 mM | 0.0222 mL | 0.1110 mL | 0.2220 mL | 0.5550 mL | |
| 80 mM | 0.0167 mL | 0.0833 mL | 0.1665 mL | 0.4163 mL | |
| 100 mM | 0.0133 mL | 0.0666 mL | 0.1332 mL | 0.3330 mL |
Stafia-1-dipivaloyloxymethyl ester Related Classifications
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