Sulfaguanidine-13C6
Based on 1 Customer Validation
Sulfaguanidine-13C6 is the 13C6 labeled Sulfaguanidine. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.
For research use only. We do not sell to patients.
- Purity: 99.0%
- Formula: C13C6H10N4O2S
- Molecular Weight:220.20
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Antibiotic Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 57-67-0
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Appearance Solid
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Molecular Weight 220.20
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Formula C13C6H10N4O2S
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Color White to off-white
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SMILES
O=S([13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)N)(NC(N)=N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (454.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 3.33 mg/mL (15.12 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[3]. Mizuno N, et, al. Gastrointestinal absorption of sulfaguanidine in neonatal and adult rats. J Pharmacobiodyn. 1986 Oct;9(10):787-92. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 4.5413 mL | 22.7066 mL | 45.4133 mL | 113.5332 mL |
| 5 mM | 0.9083 mL | 4.5413 mL | 9.0827 mL | 22.7066 mL | |
| 10 mM | 0.4541 mL | 2.2707 mL | 4.5413 mL | 11.3533 mL | |
| 15 mM | 0.3028 mL | 1.5138 mL | 3.0276 mL | 7.5689 mL | |
| DMSO | 20 mM | 0.2271 mL | 1.1353 mL | 2.2707 mL | 5.6767 mL |
| 25 mM | 0.1817 mL | 0.9083 mL | 1.8165 mL | 4.5413 mL | |
| 30 mM | 0.1514 mL | 0.7569 mL | 1.5138 mL | 3.7844 mL | |
| 40 mM | 0.1135 mL | 0.5677 mL | 1.1353 mL | 2.8383 mL | |
| 50 mM | 0.0908 mL | 0.4541 mL | 0.9083 mL | 2.2707 mL | |
| 60 mM | 0.0757 mL | 0.3784 mL | 0.7569 mL | 1.8922 mL | |
| 80 mM | 0.0568 mL | 0.2838 mL | 0.5677 mL | 1.4192 mL | |
| 100 mM | 0.0454 mL | 0.2271 mL | 0.4541 mL | 1.1353 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.