2. Apoptosis
  3. Apoptosis
  4. SWQIGGN

SWQIGGN is an oligopeptide targeting ovarian cancer cells. SWQIGGN inhibits the viability, proliferation, migration, invasion and cell adhesion of ovarian cancer cells and promotes apoptosis. SWQIGGN reduces ascites volume and tumor nodule formation in mouse models. SWQIGGN can be used in studies related to ovarian cancer.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

SWQIGGN

SWQIGGN Chemical Structure

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

SWQIGGN Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

SWQIGGN is an oligopeptide targeting ovarian cancer cells. SWQIGGN inhibits the viability, proliferation, migration, invasion and cell adhesion of ovarian cancer cells and promotes apoptosis. SWQIGGN reduces ascites volume and tumor nodule formation in mouse models. SWQIGGN can be used in studies related to ovarian cancer[1][2].

In Vitro

SWQIGGN specifically binds to human ovarian cancer cell line HO8910, but does not bind to normal human ovarian epithelial cell line OSE[2].
SWQIGGN (10 μM; 1-7 days) significantly reduces the viability of human ovarian cancer HO8910 cells[2].
SWQIGGN (48 h) potently inhibits the invasive ability of human ovarian cancer HO8910 cells in vitro[2].
SWQIGGN (48 h) potently inhibits the migration of human ovarian cancer HO8910 cells in vitro[2].
SWQIGGN (for 5 days) significantly reduces the in vitro adhesion ability of human ovarian cancer HO8910 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SWQIGGN Related Antibodies

Cell Viability Assay[2]

Cell Line: human ovarian cancer HO8910 cells
Concentration: 10 μM
Incubation Time: 1, 2, 3, 4, 5, 6 and 7 days
Result: Showed no significant difference in cell viability compared to controls on days 1 and 2.
Significantly reduced HO8910 cell viability compared to control groups from day 3 to day 6, with absorbance values at 492 nm consistently lower in the SWQIGGN group.

Cell Invasion Assay[2]

Cell Line: human ovarian cancer HO8910 cells
Concentration: 10 μM
Incubation Time: 48 h
Result: Inhibited invasion, reducing the average number of invading cells by more than 50% compared to controls.

Cell Migration Assay [2]

Cell Line: human ovarian cancer HO8910 cells
Concentration: 10 μM
Incubation Time: 48 h
Result: Potently inhibited migration, reducing the average number of migrating cells by more than 80% compared to controls.
In Vivo

SWQIGGN inhibits ovarian cancer growth and metastasis in nude mice, reducing total tumor weight by 70.62%, suppressing VEGF expression, and increasing tumor cell apoptosis[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

760.79

Formula

C33H48N10O11
Sequence

Ser-Trp-Gln-Ile-Gly-Gly-Asn
Sequence Shortening

SWQIGGN
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

SWQIGGN Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SWQIGGNApoptosiscell migrationovarian cancer cellshuman ovarian cancer HO8910 cellsVEGFcell proliferationmouse modelsapoptosisnormal human ovarian epithelial OSE cellsnude micecell viabilityInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
SWQIGGN
Cat. No.:
HY-P11854
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.